Výsledky vyhledávání - "Barbara L. Brown"

Autor: Joanne Waller, Barbara L. Brown, Joan S. Baizer, Dagmar Timmann, Mitchell Glickstein

Publikováno v: The Cerebellum. 4:189-197

We tested monkeys, patients, and normal control human subjects in a task that requires skilled use of the fingers. Animals and patients with lesions of the cerebellum, particularly of the cerebellar hemispheres, were severely impaired in retrieving r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c43a4fe843e6d284bb00e961909dc1f
https://doi.org/10.1080/14734220500201627

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Outpatient erythropoietin administered through a protocol-driven, pharmacist-managed program may produce significant patient and economic benefits

Autor: Ion D, Bucaloiu, Gwendolyn, Akers, Maria C, Bermudez, Roshan, Mainali, Barbara L, Brown, Stephanie S, Roberts, James E, Hartle

Publikováno v: Managed care interface. 20(6)

To assess the effect of a disease management program in anemia of chronic kidney disease (CKD), the authors reviewedthe records of all adults treated with epoetin alfa (EPO) at their institution between September 2003 and April 2006 and compared them

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::54e958c88edef1b513efb51f649bf562
https://pubmed.ncbi.nlm.nih.gov/17708080

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The effects of inhalation exposure to bromo-dichloromethane on specific rat CYP isoenzymes

Autor: Rex A. Pegram, Barbara L. Brown, Guangyu Zhao, John W. Allis

Publikováno v: Toxicology. 161(1-2)

Several cytochrome P450 (CYP) isoenzymes may be involved in the metabolism of bromo-dichloromethane (BDCM), a drinking water disinfection byproduct. After 4-h inhalation exposures of male F344 rats to BDCM between 100 and 3200 p.p.m., hepatic microso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44817549773a66b5117b628cc8489039
https://pubmed.ncbi.nlm.nih.gov/11295256

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Methanol potentiation of carbon tetrachloride hepatotoxicity: the central role of cytochrome P450

Autor: Jane Ellen Simmons, John W. Allis, Barbara L. Brown, Dennis E. House, Anthony McDonald, Gary E. Hatch

Publikováno v: Toxicology. 112(2)

Evidence to explain the enhanced hepatotoxicity of carbon tetrachloride (CCl4) following methanol exposure by inhalation is presented. Hepatic microsomes prepared from male F344 rats exposed to methanol at concentrations up to 10,000 ppm showed incre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec28889c14df0fd4547560d79a6d006
https://pubmed.ncbi.nlm.nih.gov/8814342

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Fasting for less than 24 h induces cytochrome P450 2E1 and 2B1/2 activities in rats

Autor: Jane Ellen Simmons, Barbara L. Brown, Dennis E. House, John W. Allis

Publikováno v: Toxicology letters. 81(1)

Cytochrome P450 (CYP) 2E1 activity is induced after 24 h of fasting but no information is available for shorter fasting periods. We investigate the induction of CYP 2E1, 2B1/2 and 1A1 in young adult male F344 rats after 8, 16 and 24 h of fasting comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aa78aa1f8ebaf20758d1b5c9ffec6a3
https://pubmed.ncbi.nlm.nih.gov/8525497

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Methotrexate analogs. 6. Replacement of glutamic acid by various amino acid esters and amines

Autor: Edward J. Modest, Barbara L. Brown, Michael Chaykovsky

Publikováno v: Journal of Medicinal Chemistry. 18:909-912

A series of methotrexate (MTX) analogs was prepared in which the glutamic acid moiety is replaced by various amino acid esters and amines. The synthetic method consisted of the reaction of 4-amino-4-deoxy-N10-methylpteroic acid with various reagents

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f30ad1a72bf74597c166a57d1f91611
https://doi.org/10.1021/jm00243a010

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Maternal Stress Decreases Steroid Aromatase Activity in Brains of Male and Female Rat Fetuses

Autor: Barbara L. Brown, Judith Weisz, Ingeborg L. Ward

Publikováno v: Neuroendocrinology. 35:374-379

Steroid aromatase activity was measured in homogenates of combined hypothalamic and amygdaloid specimens obtained from 17- to 21-day-old male and female rat fetuses. The fetuses were obtained both fro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::092b3c1356fa53179f7e3ad8870b053a
https://doi.org/10.1159/000123410

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