Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Barbara L, Kee"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/48f2a5a0d8ed4feda7fdb9dccac44129
Autor:
Geoffrey Parriott, Barbara L. Kee
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
T Lymphocyte Acute Lymphoblastic Leukemia (ALL) is an aggressive disease arising from transformation of T lymphocytes during their development. The mutation spectrum of T-ALL has revealed critical regulators of the growth and differentiation of norma
Externí odkaz:
https://doaj.org/article/ccb3e60611494f73ac4498efdca0bcc7
Autor:
Tiffany Carr, Stephanie McGregor, Sheila Dias, Mihalis Verykokakis, Michelle M. Le Beau, Hai-Hui Xue, Mikael Sigvardsson, Elizabeth T. Bartom, Barbara L. Kee
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
T lymphocyte acute lymphoblastic leukemia (T-ALL) is a heterogeneous disease affecting T cells at multiple stages of their development and is characterized by frequent genomic alterations. The transcription factor LEF1 is inactivated through mutation
Externí odkaz:
https://doaj.org/article/9767a5a342b047c4984266c9b929c2b1
Autor:
Duy Pham, Carson E. Moseley, Min Gao, Daniel Savic, Colleen J. Winstead, Mengxi Sun, Barbara L. Kee, Richard M. Myers, Casey T. Weaver, Robin D. Hatton
Publikováno v:
Cell Reports, Vol 29, Iss 5, Pp 1203-1220.e7 (2019)
Summary: The basic leucine zipper transcription factor activating transcription factor-like (Batf) contributes to transcriptional programming of multiple effector T cells and is required for T helper 17 (Th17) and T follicular helper (Tfh) cell devel
Externí odkaz:
https://doaj.org/article/5c538b770140414a9fd2816fdd9f10e0
Autor:
Aditi Chandra, Sora Yoon, Michaël F. Michieletto, Naomi Goldman, Emily K. Ferrari, Maryam Abedi, Isabelle Johnson, Maria Fasolino, Kenneth Pham, Leonel Joannas, Barbara L. Kee, Jorge Henao-Mejia, Golnaz Vahedi
Publikováno v:
Immunity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c1d08e1173ce1581114d197991732e3
https://doi.org/10.1016/j.immuni.2023.05.004
https://doi.org/10.1016/j.immuni.2023.05.004
Autor:
Geoffrey Parriott, Emma Hegermiller, Rosemary E. Morman, Cameron Frank, Caner Saygin, Wendy Stock, Elizabeth T. Bartom, Barbara L. Kee
Publikováno v:
bioRxiv
T lymphocyte acute lymphoblastic leukemia (T-ALL) is frequently associated with increased expression of the E protein transcription factor inhibitors TAL1 and LYL1. In mouse models, ectopic expression of Tal1 or Lyl1 in T cell progenitors or inactiva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf2a4297883f4a87bd161ba67c086ef8
https://doi.org/10.1101/2023.04.23.537993
https://doi.org/10.1101/2023.04.23.537993
Autor:
Aditi Chandra, Sora Yoon, Michael F. Michieletto, Naomi Goldman, Emily K. Ferrari, Maria Fasolino, Leonel Joannas, Barbara L. Kee, Jorge Henao-Mejia, Golnaz Vahedi
Multi-enhancer hubs are spatial clusters of enhancers which have been recently characterized across numerous developmental programs. Yet, the functional relevance of these three-dimensional (3D) structures is poorly understood. Here we show that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0922304744d155065471b890bae7aa2d
https://doi.org/10.1101/2022.10.28.514213
https://doi.org/10.1101/2022.10.28.514213
Autor:
Roxroy C. Morgan, Cameron Frank, Munmun Greger, Mikael Sigvardsson, Elizabeth T. Bartom, Barbara L. Kee
Interferon-γ producing invariant natural killer T (iNKT1) cells are lipid reactive innate-like lymphocytes that are resident in the thymus and peripheral tissues where they protect against pathogenic infection. The thymic functions of iNKT1 cells ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20efdb1d610aca51836260e1131becf2
https://doi.org/10.1101/2022.10.23.513409
https://doi.org/10.1101/2022.10.23.513409
Autor:
Yiran Liu, Cher Sha, Alberto Ambesi-Impiombato, Michael C. Ostrowski, Erin Kim, Theresa M. Keeley, Jahnavi K. Nalamolu, Qing Wang, Mark Y. Chiang, Adolfo A. Ferrando, Ran Yan, Rohan Kodgule, Russell J.H. Ryan, Arvind Rao, Nicholas Kunnath, Linda C. Samuelson, Barbara L. Kee, Giusy Della Gatta, Anna C. McCarter, Rork Kuick, Ashley Melnick, Mengxi Sun
Publikováno v:
Blood Cancer Discov
Notch activation is highly prevalent among cancers, in particular T-cell acute lymphoblastic leukemia (T-ALL). However, the use of pan-Notch inhibitors to treat cancers has been hampered by adverse effects, particularly intestinal toxicities. To circ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8b842e2f9d5afeb347ec0996b550218
https://doi.org/10.1158/2643-3230.bcd-20-0026
https://doi.org/10.1158/2643-3230.bcd-20-0026
Publikováno v:
J Immunol
Lymphocyte lineage specification and commitment requires the activation of lineage-specific genes and repression of alternative lineage genes, respectively. The mechanisms governing alternative lineage gene repression and commitment in lymphocytes ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9298dd76c03a96160b3bc76a2b398219
https://doi.org/10.4049/jimmunol.1901188
https://doi.org/10.4049/jimmunol.1901188