Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Barbara Knighton"'
Autor:
Evelyn de Groot, Sruthy Varghese, Lin Tan, Barbara Knighton, Mary Sobieski, Nghi Nguyen, Yong Sung Park, Reid Powell, Philip L. Lorenzi, Bin Zheng, Clifford Stephan, Y. N. Vashisht Gopal
Publikováno v:
Cancer & Metabolism, Vol 10, Iss 1, Pp 1-18 (2022)
Abstract Background Primary and posttreatment resistance to BRAFV600 mutation–targeting inhibitors leads to disease relapse in a majority of melanoma patients. In many instances, this resistance is promoted by upregulation of mitochondrial oxidativ
Externí odkaz:
https://doaj.org/article/b8198ca78c77420fbbfe89e1bf6a9d77
Autor:
Y.N. Vashisht Gopal, Weiyi Peng, Jason Roszik, Yared Hailemichael, Jennifer L. McQuade, Andrew L. Mackinnon, Philip L. Lorenzi, Lin Tan, Barbara Knighton, Catherine K. Luo, Grant M. Fischer, Courtney W. Hudgens, Hannah R. Hodges, Leila J. Williams, Snigdha Pramanik, Sruthy Varghese
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc8bdef8d6767b64612e936048845ca
https://doi.org/10.1158/1535-7163.22520512.v1
https://doi.org/10.1158/1535-7163.22520512.v1
Autor:
Michael A. Davies, Michael T. Tetzlaff, Sheri L. Holmen, Jianjun Zhang, Joseph R. Marszalek, Ralph J. DeBerardinis, Alexander J. Lazar, Nagireddy Putluri, P. Andrew Futreal, Jennifer A. Wargo, Jason T. Huse, Patrick Hwu, Y. N. Vashisht Gopal, Jeffrey E. Gershenwald, Isabella C. Glitza, Hussein A. Tawbi, Sherise D. Ferguson, Wanleng Deng, Barbara Knighton, Courtney W. Hudgens, Arun Sreekumar, Chandrashekar R. Ambati, Anuj Srivastava, Chendong Yang, Fernando C. L. Carapeto, Mariana P. de Macedo, Alexandre Reuben, Aron Y. Joon, Lauren E. Haydu, Jennifer L. McQuade, Won-Chul Lee, David A. Kircher, Ali Jalali, Grant M. Fischer
Table S1: Clinical Characteristics of Melanoma Brain Metastases, Extracranial Metastases, and Primary Tumors. Tab 1. Clinical data for the MBMs and ECMs from melanoma patients utilized in this manuscript. Tab 2. Clinical data for primary melanomas fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::148f98af1114c021ea7fd51f54fd55bd
https://doi.org/10.1158/2159-8290.22535959
https://doi.org/10.1158/2159-8290.22535959
Autor:
Michael A. Davies, Michael T. Tetzlaff, Sheri L. Holmen, Jianjun Zhang, Joseph R. Marszalek, Ralph J. DeBerardinis, Alexander J. Lazar, Nagireddy Putluri, P. Andrew Futreal, Jennifer A. Wargo, Jason T. Huse, Patrick Hwu, Y. N. Vashisht Gopal, Jeffrey E. Gershenwald, Isabella C. Glitza, Hussein A. Tawbi, Sherise D. Ferguson, Wanleng Deng, Barbara Knighton, Courtney W. Hudgens, Arun Sreekumar, Chandrashekar R. Ambati, Anuj Srivastava, Chendong Yang, Fernando C. L. Carapeto, Mariana P. de Macedo, Alexandre Reuben, Aron Y. Joon, Lauren E. Haydu, Jennifer L. McQuade, Won-Chul Lee, David A. Kircher, Ali Jalali, Grant M. Fischer
There is a critical need to improve our understanding of the pathogenesis of melanoma brain metastases (MBM). Thus, we performed RNA sequencing on 88 resected MBMs and 42 patient-matched extracranial metastases; tumors with sufficient tissue also und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45fe37c67c89f90e93ffd1ae70dd8269
https://doi.org/10.1158/2159-8290.c.6547993.v1
https://doi.org/10.1158/2159-8290.c.6547993.v1
Autor:
Y.N. Vashisht Gopal, Weiyi Peng, Jason Roszik, Yared Hailemichael, Jennifer L. McQuade, Andrew L. Mackinnon, Philip L. Lorenzi, Lin Tan, Barbara Knighton, Catherine K. Luo, Grant M. Fischer, Courtney W. Hudgens, Hannah R. Hodges, Leila J. Williams, Snigdha Pramanik, Sruthy Varghese
Supplementary tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6792f38fa34d433328eca682e72fea0a
https://doi.org/10.1158/1535-7163.22520509.v1
https://doi.org/10.1158/1535-7163.22520509.v1
Autor:
Y.N. Vashisht Gopal, Weiyi Peng, Jason Roszik, Yared Hailemichael, Jennifer L. McQuade, Andrew L. Mackinnon, Philip L. Lorenzi, Lin Tan, Barbara Knighton, Catherine K. Luo, Grant M. Fischer, Courtney W. Hudgens, Hannah R. Hodges, Leila J. Williams, Snigdha Pramanik, Sruthy Varghese
Immune-checkpoint inhibitors and adoptive tumor-infiltrating lymphocyte (TIL) therapies have profoundly improved the survival of patients with melanoma. However, a majority of patients do not respond to these agents, and many responders experience di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9898323fc1f4375448cd5638a032e4b2
https://doi.org/10.1158/1535-7163.c.6542659.v1
https://doi.org/10.1158/1535-7163.c.6542659.v1
Autor:
Michael A. Davies, Michael T. Tetzlaff, Sheri L. Holmen, Jianjun Zhang, Joseph R. Marszalek, Ralph J. DeBerardinis, Alexander J. Lazar, Nagireddy Putluri, P. Andrew Futreal, Jennifer A. Wargo, Jason T. Huse, Patrick Hwu, Y. N. Vashisht Gopal, Jeffrey E. Gershenwald, Isabella C. Glitza, Hussein A. Tawbi, Sherise D. Ferguson, Wanleng Deng, Barbara Knighton, Courtney W. Hudgens, Arun Sreekumar, Chandrashekar R. Ambati, Anuj Srivastava, Chendong Yang, Fernando C. L. Carapeto, Mariana P. de Macedo, Alexandre Reuben, Aron Y. Joon, Lauren E. Haydu, Jennifer L. McQuade, Won-Chul Lee, David A. Kircher, Ali Jalali, Grant M. Fischer
Supplemental Methods; Supplemental References
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6743e0d761222fba166485d60f9ef92c
https://doi.org/10.1158/2159-8290.22535962
https://doi.org/10.1158/2159-8290.22535962
Autor:
Michael A. Davies, Michael T. Tetzlaff, Sheri L. Holmen, Jianjun Zhang, Joseph R. Marszalek, Ralph J. DeBerardinis, Alexander J. Lazar, Nagireddy Putluri, P. Andrew Futreal, Jennifer A. Wargo, Jason T. Huse, Patrick Hwu, Y. N. Vashisht Gopal, Jeffrey E. Gershenwald, Isabella C. Glitza, Hussein A. Tawbi, Sherise D. Ferguson, Wanleng Deng, Barbara Knighton, Courtney W. Hudgens, Arun Sreekumar, Chandrashekar R. Ambati, Anuj Srivastava, Chendong Yang, Fernando C. L. Carapeto, Mariana P. de Macedo, Alexandre Reuben, Aron Y. Joon, Lauren E. Haydu, Jennifer L. McQuade, Won-Chul Lee, David A. Kircher, Ali Jalali, Grant M. Fischer
Figs. S1-S14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e91c887ec7f059e8e86999559662066
https://doi.org/10.1158/2159-8290.22535965
https://doi.org/10.1158/2159-8290.22535965
Autor:
Y.N. Vashisht Gopal, Weiyi Peng, Jason Roszik, Yared Hailemichael, Jennifer L. McQuade, Andrew L. Mackinnon, Philip L. Lorenzi, Lin Tan, Barbara Knighton, Catherine K. Luo, Grant M. Fischer, Courtney W. Hudgens, Hannah R. Hodges, Leila J. Williams, Snigdha Pramanik, Sruthy Varghese
Supplementary figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a95416c428b8a080d37331b9067f8b7
https://doi.org/10.1158/1535-7163.22520515.v1
https://doi.org/10.1158/1535-7163.22520515.v1
Autor:
Swaminathan Kumar, Courtney W. Hudgens, Lauren E. Haydu, Michael A. Davies, Alexander J. Lazar, Qianghua Hu, Michael T. Tetzlaff, Barbara Knighton, Aron Y. Joon, Renato Guerrieri, Wanleng Deng, Grant M. Fischer, Y.N. Vashisht Gopal, Jennifer L. McQuade
Publikováno v:
Neuro-oncology Advances
BackgroundRecently, we showed that melanoma brain metastases (MBMs) are characterized by increased utilization of the oxidative phosphorylation (OXPHOS) metabolic pathway compared to melanoma extracranial metastases (ECMs). MBM growth was inhibited b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2812ebd290ea822daeb824fe3b1f0408
http://europepmc.org/articles/PMC7865080
http://europepmc.org/articles/PMC7865080