Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Barbara K. Klein"'
Autor:
Pia Björck, Walter J. Storkus, Wen-Rong Lie, Susan L. Woulfe, Walter C. Olson, Barbara K. Klein
Publikováno v:
International Journal of Cancer. 100:586-591
Progenipoietin (ProGP-4) is a chimeric molecule, exhibiting both Flt-3 and granulocyte-colony stimulating factor (G-CSF) receptor agonist activities. Subcutaneous administration of ProGP-4 to BALB/c mice at a dose of 40–100 μg/day for up to 12 con
Autor:
Yatin R. Gokarn, Edward E. Remsen, Yiqing G. Feng, Joseph B. Monahan, Cindy Jarvis, Roger J. Schilling, Barbara K. Klein, William F. Hood, Joseph K. Welply, Jeng-Jong J. Shieh, John P. Mckearn, William D. Joy, Joseph O. Polazzi
Publikováno v:
Biochemistry. 40:13598-13606
Myelopoietins (MPOs) are a family of recombinant chimeric proteins that are both interleukin-3 (IL-3) receptor and granulocyte colony-stimulating factor (G-CSF) receptor agonists. In this study, MPO molecules containing one of three different IL-3 re
Autor:
Jeng-Jong Shieh, Peter O. Olins, Maire Helena Caparon, William F. Hood, Kumnan Paik, Ann M. Donnelly, Bauer Christopher S, John P. McKearn, Sarah R. Braford, Polazzi Joseph O, John W. Thomas, Jon A. Klover, Alan Michael Easton, David L. Zeng, Mark Allen Abrams, Joseph K. Welply, Barbara K. Klein
Publikováno v:
Experimental Hematology. 27:1746-1756
A combinatorial mutagenesis strategy was used to create a collection of nearly 500 variants of human interleukin 3 (IL-3), each with four to nine amino acid substitutions clustered within four linear, nonoverlapping regions of the polypeptide. The va
Publikováno v:
Journal of Molecular Biology. 259:524-541
The three-dimensional structure and backbone dynamics of a truncated and multiply substituted recombinant human interleukin-3 (IL-3) variant (SC-65369) have been determined from multidimensional heteronuclear nuclear magnetic resonance spectroscopic
Autor:
Larry E, Kahn, Parul D, Doshi, Kelly L, McGarity, Mingfu, Yu, Christine P, Bono, Wen-Rong, Lie, Anne M, Rankin, Mary L, Smidt, Philip R, Streeter, Barbara K, Klein, Joseph K, Welply, Susan L, Woulfe
Publikováno v:
Medical science monitor : international medical journal of experimental and clinical research. 8(12)
Progenipoietin-4 (ProGP-4) is an E. coli derived chimeric growth factor that activates the human Flt3 and G-CSF receptors. ProGP-4 possesses cross-species activity and treatment of mice with ProGP-4 results in increases in the number of WBC and Class
Autor:
Pia, Björck, Wen-Rong, Lie, Susan L, Woulfe, Barbara K, Klein, Walter, Olson, Walter J, Storkus
Publikováno v:
International journal of cancer. 100(5)
Progenipoietin (ProGP-4) is a chimeric molecule, exhibiting both Flt-3 and granulocyte-colony stimulating factor (G-CSF) receptor agonist activities. Subcutaneous administration of ProGP-4 to BALB/c mice at a dose of 40-100 microg/day for up to 12 co
Autor:
William F. Hood, Barbara K. Klein, Yiqing Feng, Charles A. McWherter, Kumnan Paik, John P. McKearn
Publikováno v:
The Journal of biological chemistry. 272(36)
Interleukin-3 (IL-3) is a member of the cytokine superfamily that promotes multi-potential hematopoietic cell growth by interacting with a cell surface receptor composed of alpha and beta chains. The newly available three-dimensional structure of a v
Autor:
Guy della-Cioppa, S. Christopher Bauer, Mary L. Taylor, Dean E. Rochester, Barbara K. Klein, Dilip M. Shah, Robert T. Fraley, Ganesh M. Kishore
Publikováno v:
Nature Biotechnology. 5:579-584
Targeting a Herbicide–Resistant Enzyme from Escherichia Coli to Chloroplasts of Higher Plants