Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Barbara K Martin"'
Autor:
Elke Jordan, Golam Kabir, Stephanie Schultz, Günter Silbernagl, Darja Schmidt, Victoria A Jenkins, Heinz Weidenthaler, Daria Stroukova, Barbara K Martin, Laurence De Moerlooze
Publikováno v:
The Journal of Infectious Diseases.
Background Respiratory syncytial virus (RSV) causes significant disease burden in older adults. MVA-BN-RSV is a novel poxvirus-vectored vaccine encoding internal and external RSV proteins. Methods In a phase 2a randomized double-blind, placebo-contro
Autor:
Elke Jordan, Golam Kabir, Stephanie Schultz, Günter Silbernagl, Darja Schmidt, Victoria A. Jenkins, Heinz Weidenthaler, Daria Stroukova, Barbara K. Martin, Laurence De Moerlooze
BackgroundRespiratory syncytial virus (RSV) causes significant disease burden in infants and older adults. Most vaccines in development focus on the virus’s F protein. MVA-BN-RSV is a novel vectored vaccine encoding internal and external proteins f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4b0805f60abee5ea9fb8570fc861c04
https://doi.org/10.1101/2022.12.02.22283030
https://doi.org/10.1101/2022.12.02.22283030
Autor:
Barbara K. Martin
Publikováno v:
Principles and Practice of Clinical Trials ISBN: 9783319526775
Principles and Practice of Clinical Trials
Principles and Practice of Clinical Trials
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::781b865164299670cbb4779b2468f143
https://doi.org/10.1007/978-3-319-52677-5_267-1
https://doi.org/10.1007/978-3-319-52677-5_267-1
Autor:
Constantine Frangakis, Curtis L. Meinert, Anton P. Porsteinsson, Jacobo Mintzer, Cynthia A. Munro, Peter V. Rabins, Lon S. Schneider, Paul B. Rosenberg, Lea T. Drye, Barbara K. Martin, Daniel Weintraub, Constantine G. Lyketsos, Crystal V. Flynn Longmire
Publikováno v:
The American Journal of Geriatric Psychiatry. 22:14-24
Objective We wanted to assess if sertraline treatment (versus placebo) or remission of depression at 12 weeks (versus nonremission) in Alzheimer patients is associated with improved caregiver well being. Methods We conducted a randomized, double-blin
Experience Corps: A dual trial to promote the health of older adults and children's academic success
Autor:
Michelle C. Carlson, Laprisha Berry-Vaughn, Iveris L. Martinez, George W. Rebok, Barbara K. Martin, John F. Stewart, Elizabeth K. Tanner, Teresa E. Seeman, Kevin D. Frick, Rachel L. Piferi, Sylvia McGill, Qian Li Xue, Tara L. Gruenewald, Linda P. Fried, Erwin J. Tan, Constantine Frangakis, Kay Dickersin, Paul R. Willging, Jeremy Barron
Publikováno v:
Contemporary clinical trials
BackgroundAs the population ages, older adults are seeking meaningful, and impactful, post-retirement roles. As a society, improving the health of people throughout longer lives is a major public health goal. This paper presents the design and ration
Autor:
Avramopoulos Dimitri, Constantine G. Lyketsos, Peter V. Rabins, Lea T. Drye, Cynthia A. Munro, Matthew E. Peters, Vijay Vaidya, Curtis L. Meinert, Constantine Frangakis, Paul B. Rosenberg, Anton P. Porsteinsson, Lon S. Schneider, Jacobo Mintzer, Barbara K. Martin, Daniel Weintraub
Publikováno v:
Journal of Geriatric Psychiatry and Neurology. 24:222-228
Objective. To assess the potential for genetic influences on sertraline treatment efficacy for depression of Alzheimer disease (dAD). Four functional genetic variants were studied: 2 serotonin receptors (HTR2A-T102C and HTR2C-Cys23Ser), the serotonin
Autor:
Lea T, Drye, Barbara K, Martin, Constantine E, Frangakis, Curtis L, Meinert, Jacobo E, Mintzer, Cynthia A, Munro, Anton P, Porsteinsson, Peter V, Rabins, Paul B, Rosenberg, Lon S, Schneider, Daniel, Weintraub, Constantine G, Lyketsos, Ju, Zhang
Publikováno v:
International Journal of Geriatric Psychiatry. 26:573-583
Objective To determine if the effect of sertraline in the depression in Alzheimer's disease study – 2 (DIADS-2) differed in subgroups of patients defined by baseline depression criteria. Methods DIADS-2 was a randomized, parallel, placebo-controlle
Autor:
Lon S. Schneider, Constantine Frangakis, Jacobo Mintzer, Barbara K. Martin, Constantine G. Lyketsos, Anton P. Porsteinsson, Paul B. Rosenberg, Curtis L. Meinert, Cynthia A. Munro, Peter V. Rabins, Daniel Weintraub, Lea T. Drye
Publikováno v:
The American Journal of Geriatric Psychiatry. 18:332-340
Background Depression and antidepressant use are common in Alzheimer disease (AD), but the effect of antidepressant treatment for depression on longer term outcomes is unknown. The authors report the Week-24 outcomes of patients who participated in a
Autor:
Paul B. Rosenberg, Cynthia A. Munro, Lea T. Drye, Daniel Weintraub, Curtis L. Meinert, Constantine Frangakis, Peter V. Rabins, Constantine G. Lyketsos, Jacobo Mintzer, Anton P. Porsteinsson, Lon S. Schneider, Barbara K. Martin
Publikováno v:
The American Journal of Geriatric Psychiatry. 18:136-145
Objective Depression is common in Alzheimer disease (AD), and antidepressants are commonly used for its treatment, however, evidence for antidepressant efficacy in this population is lacking. The authors conducted a multicenter, randomized, placebo-c
Autor:
Peter V. Finn, Joseph L. Pater, Ernest T. Hawk, Curtis L. Meinert, Gretchen Arndt, Nadir Arber, Barbara K. Martin, Jonghyeon Kim, Paul E. Goss, Bernard Levin, Peter Lance, Scott D. Solomon, Emily Y. Chew, Jaye L. Viner, Stefanie Obara, Robert A. Fowler, Janet Wittes, Monica M. Bertagnolli
Publikováno v:
Circulation. 117:2104-2113
Background— Observational studies and randomized trials have reported increased cardiovascular risk associated with cyclooxygenase-2 inhibitors. Prior placebo-controlled randomized studies had limited ability to assess the relationship of either ce