Comparison of morbidity and mortality after bloodstream infection with vancomycin-resistant versus -susceptible Enterococcus faecium: a nationwide cohort study in Denmark, 2010–2019

Autor: Peter Bager, Jonas Kähler, Mikael Andersson, Barbara Juliane Holzknecht, Sanne Grønvall Kjær Hansen, Kristian Schønning, Karen Leth Nielsen, Kristoffer Koch, Mette Pinholt, Marianne Voldstedlund, Anders Rhod Larsen, Brian Kristensen, Kåre Mølbak, Ute Wolff Sönksen, Sissel Skovgaard, Robert Skov, Anette M. Hammerum

Publikováno v: Emerging Microbes and Infections, Vol 13, Iss 1 (2024)

ABSTRACTThe emergence of bloodstream infections (BSI) caused by vancomycin-resistant Enterococci (VRE) has caused concern. Nonetheless, it remains unclear whether these types are associated with an excess risk of severe outcomes when compared with in

Externí odkaz: https://doaj.org/article/d58cd4b46af24149b6434cec9357830f

Risk factors for methicillin-resistant Staphylococcus aureus colonization in a level-IV neonatal intensive care unit: a retrospective study

Autor: Julia Elzbieta Galuszka, Kim Thomsen, Jenny Dahl Knudsen, Rikke Louise Stenkjaer, Rikke Nielsen, Karen Leth Nielsen, Andreas Petersen, Barbara Juliane Holzknecht, Mette Damkjaer Bartels, Morten Breindahl, Lise Aunsholt

Publikováno v: Antimicrobial Stewardship & Healthcare Epidemiology, Vol 3 (2023)

Abstract Objective: To identify risk factors associated with methicillin-resistant Staphylococcus aureus (MRSA) colonization in neonatal patients during an MRSA outbreak to minimize future outbreaks. Design: Retrospective case-control study. Set

Externí odkaz: https://doaj.org/article/c205b3d7c5084c02a00b252f06310cf2

Shorter Total Length of Stay After Intraperitoneal Fosfomycin, Metronidazole, and Molgramostim for Complicated Appendicitis: A Pivotal Quasi-Randomized Controlled Trial

Autor: Siv Fonnes, Søren Roepstorff, Barbara Juliane Holzknecht, Christoffer Skov Olesen, Joachim Hjalde Halmsted Olsen, Line Schmidt, Rasmus Alder, Sara Gamborg, Tilde Rasmussen, Magnus Arpi, Lars Nannestad Jørgensen, Jacob Rosenberg

Publikováno v: Frontiers in Surgery, Vol 7 (2020)

Background: We aimed to investigate the difference in the total length of hospital stay (LOS) after intraperitoneal vs. intravenous antibiotic treatment in patients with complicated appendicitis.Methods: We conducted a quasi-randomized prospective cl

Externí odkaz: https://doaj.org/article/0ff1aea2f4fe45a6b26e48b071d85250

Contaminated dicloxacillin capsules as the source of an NDM-5/OXA-48-producing Enterobacter hormaechei ST79 outbreak, Denmark and Iceland, 2022 and 2023

Autor: Charlotte Nielsen Agergaard, Lone Jannok Porsbo, Thomas Vognbjerg Sydenham, Sanne Grønvall Kjær Hansen, Kat Steinke, Sanne Løkkegaard Larsen, Kristján Orri Helgason, Frank Hansen, Kasper Thystrup Karstensen, Anna E Henius, Barbara Juliane Holzknecht, Lillian Søes, Kristian Schønning, Mikala Wang, Nina Ank, Anna Margrét Halldórsdóttir, Ólafur Guðlaugsson, Anette M Hammerum, Anne Kjerulf, Brian Kristensen, Henrik Hasman, Ulrik Stenz Justesen

Publikováno v: Agergaard, C N, Porsbo, L J, Sydenham, T V, Hansen, S G K, Steinke, K, Larsen, S L, Helgason, K O, Hansen, F, Karstensen, K T, Henius, A E, Holzknecht, B J, Søes, L, Schønning, K, Wang, M, Ank, N, Halldórsdóttir, A M, Guðlaugsson, Ó, Hammerum, A M, Kjerulf, A, Kristensen, B, Hasman, H & Justesen, U S 2023, ' Contaminated dicloxacillin capsules as the source of an NDM-5/OXA-48-producing Enterobacter hormaechei ST79 outbreak, Denmark and Iceland, 2022 and 2023 ', Eurosurveillance, vol. 28, no. 9 . https://doi.org/10.2807/1560-7917.ES.2023.28.9.2300108
Agergaard, C N, Porsbo, L J, Sydenham, T V, Hansen, S G K, Steinke, K, Larsen, S L, Helgason, K O, Hansen, F, Karstensen, K T, Henius, A E, Holzknecht, B J, Søes, L, Schønning, K, Wang, M, Ank, N, Halldórsdóttir, A M, Guðlaugsson, Ó, Hammerum, A M, Kjerulf, A, Kristensen, B, Hasman, H & Justesen, U S 2023, ' Contaminated dicloxacillin capsules as the source of an NDM-5/OXA-48-producing Enterobacter hormaechei ST79 outbreak, Denmark and Iceland, 2022 and 2023 ', Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, vol. 28, no. 9 . https://doi.org/10.2807/1560-7917.ES.2023.28.9.2300108

From October 2022 through January 2023, nine patients with NDM-5/OXA-48-carbapenemase-producing Enterobacter hormaechei ST79 were detected in Denmark and subsequently one patient in Iceland. There were no nosocomial links between patients, but they h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5150eca4dc139fd736e846be5156baa1
https://vbn.aau.dk/ws/files/525097322/Agergaard_et_al._2023_._Contaminated_dicloxacillin_capsules_as_the_source_of_an_NDM_5_OXA_48_producing_Enterobacter_hormaechei_ST79_outbreak_Denmark_and_Iceland_2022_and_2023.pdf

Possible misinterpretation of penicillin susceptibility in Staphylococcus aureus blood isolate due to in vitro loss of the blaZ gene

Autor: Andreas Petersen, Anders Rhod Larsen, Barbara Juliane Holzknecht, Søren Overballe-Petersen, Helle Brander Eriksen, Michael Pedersen

Publikováno v: European Journal of Clinical Microbiology & Infectious Diseases. 41:163-167

We describe a case of recurrent catheter-related blood stream infections (BSI) with Staphylococcus aureus, in which the first isolate tested susceptible to penicillin, while subsequent isolates were resistant. Phenotypic susceptibility correlated wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e71475698181180bfc5901e1ce0ed7cd
https://doi.org/10.1007/s10096-021-04344-w