Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Barbara J. Miller"'
Nanoscale ZnO Induces Cytotoxicity and DNA Damage in Human Cell Lines and Rat Primary Neuronal Cells
Autor:
Jun-Jie Yin, Qingsu Xia, Xiaoju Zou, Paul C. Howard, Frederick A. Beland, Hongtao Yu, Peter P. Fu, Shuguang Wang, Barbara J. Miller, Cheng Wang, Hsiu-Mei Chiang
Publikováno v:
Journal of Nanoscience and Nanotechnology. 12:2126-2135
The toxic effects of ZnO nanoparticles (nano-ZnO) (1-100 microg/mL) suspended in DMEM were examined in human A549 cells, HepG2 cells, human skin fibroblast cells, human skin keratinocytes, and rat primary neuronal cells for 24 h. Nano-ZnO induced dos
Autor:
Barbara L. Parsons, Paul C. Howard, Tracie L. Verkler, Robert R. Delongchamp, Peggy J. Webb, Barbara J. Miller
Publikováno v:
Molecular Carcinogenesis. 47:599-607
Sunlight and ultraviolet-induced mutation of the p53 gene is a frequent, possibly obligate step in skin cancer development, making quantitative measurement of p53 mutation an ideal biomarker for sunlight-induced skin carcinogenesis. To understand how
Autor:
James N. Atkins, Barbara J. Miller, Norman Wolmark, Terrence P. Cescon, J. Philip Kuebler, William J. John, Victor G. Vogel, Roy E. Smith, Charles E. Geyer, Samuel A. Jacobs, Linda H. Colangelo, H. Samuel Wieand
Publikováno v:
Clinical Colorectal Cancer. 5:181-187
Background Pemetrexed and oxaliplatin have clinical activity as single agents in colorectal cancer (response rates, 10%-17%). In this study, these drugs were used in combination as first-line therapy in a group of patients with metastatic colorectal
Autor:
P. Donald Forbes, Barbara J. Miller, Daniel F. Molefe, Paul C. Howard, James J. Chen, Christopher P. Sambuco, Ralph L. Kodell
Publikováno v:
Journal of Statistical Planning and Inference. 129:39-58
A multiple induction test procedure that extends a single induction test procedure proposed by Kodell and Chen (Biometrical J. 43(4) (2001) 447) based on the work of Kokoska et al. (Anticancer Res. 13 (1993) 1357) is introduced. The new procedure can
Publikováno v:
Carcinogenesis. 18:2071-2076
Uracil can arise in DNA by misincorporation of dUTP into nascent DNA and/or by cytosine deamination in established DNA. Based on recent findings, both pathways appear to be promoted in the methyl-deficient model of hepatocarcinogenesis. A chronic inc
Autor:
Diana C. Haines, James M. Phang, S N Perkins, Stephen D. Hursting, S J James, Barbara J. Miller
Publikováno v:
Carcinogenesis. 18:989-994
Transgenic mice with both alleles of the p53 tumor suppressor gene product 'knocked out' by gene targeting are susceptible to early development of tumors, chiefly lymphomas and sarcomas. Compared with the control group, administration of dehydroepian
Autor:
Carlton D. Jackson, Barbara J. Miller, Alan Warbritton, Constance C. Weis, David R. Cross, S. Jill James
Publikováno v:
Nutrition Research. 15:1487-1495
Male Fischer 344 rats, were administered NIH-31, AIN-76A, or AIN-76A plus 0.25% yeast RNA diets for 3 weeks, partially hepatectomized (PH), and groups of 6 rats from each diet group were sacrificed at 0, 2, 7 and 14 days following PH. Liver weight, t
Publikováno v:
Cell Proliferation. 27:395-406
Folate deficiency will induce abnormal deoxynucleoside triphosphate (dNTP) metabolism because folate-derived one-carbon groups are essential for de novo synthesis of purines and the pyrimidine, thymidylate. Under conditions of methionine deprivation,
Publikováno v:
Cell Proliferation. 26:327-336
Agents and conditions that induce alterations in deoxyribonucleotide pools can have important regulatory effects on the rate of DNA synthesis as well as cell cycle progression. A simplified procedure for the separation of both ribonucleoside triphosp
Publikováno v:
American Journal of Hematology. 40:176-182
The use of ibuprofen (IBP) in hemophilic men for chronic hemophilic arthropathy is associated with transient coagulation abnormalities, but usually does not cause bleeding symptoms. However, when hemophilic men are treated with ibuprofen while also r