Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Barbara J Rose"'
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200634 (2018)
While extremely rare in humans, hemangiosarcoma (HSA) accounts for nearly 2% of canine neoplasia, and is characterized by both aggressive local growth/invasion and a high rate of metastasis. Both canine and human HSA exhibit sustained aberrant PI3K/A
Externí odkaz:
https://doaj.org/article/837fe27d459f4d3abf91186279e8154b
Autor:
Junko Maeda, Coral E Froning, Colleen A Brents, Barbara J Rose, Douglas H Thamm, Takamitsu A Kato
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156689 (2016)
Canine cancer cell lines have progressively been developed, but are still underused resources for radiation biology research. Measurement of the cellular intrinsic radiosensitivity is important because understanding the difference may provide a frame
Externí odkaz:
https://doaj.org/article/9032110d238b4be1b93b4168ecb05b36
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69192 (2013)
There is accumulating evidence that an individual's inability to accurately repair DNA damage in a timely fashion may in part dictate a predisposition to cancer. Dogs spontaneously develop lymphoproliferative diseases such as lymphoma, with the golde
Externí odkaz:
https://doaj.org/article/788704d9276f4be297c269c0e74435e7
Autor:
Junko Maeda, Charles R Yurkon, Hiroshi Fujisawa, Masami Kaneko, Stefan C Genet, Erica J Roybal, Garrett W Rota, Ethan R Saffer, Barbara J Rose, William H Hanneman, Douglas H Thamm, Takamitsu A Kato
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43355 (2012)
Canine osteosarcoma (OSA) is known to present with highly variable and chaotic karyotypes, including hypodiploidy, hyperdiploidy, and increased numbers of metacentric chromosomes. The spectrum of genomic instabilities in canine OSA has significantly
Externí odkaz:
https://doaj.org/article/49d6e295ce5e487cafefba1704e6b458
Publikováno v:
BMC Veterinary Research
BMC Veterinary Research, Vol 16, Iss 1, Pp 1-9 (2020)
BMC Veterinary Research, Vol 16, Iss 1, Pp 1-9 (2020)
Background Lymphoma is a common cancer in dogs. While most dogs receiving chemotherapy experience remission, very few are cured, and median survival times are generally in the 12-month range. Novel approaches to treatment are unquestionably needed. T
Autor:
Barbara J. Rose
Publikováno v:
The Educational Forum. 82:309-320
In this essay, the author uses experiences as a teacher educator and learning from a historically significant activism movement to (a) compare values in activism-centered and education-centered organizations, (b) posit ways that the concept of neutra
Publikováno v:
BMC Cancer
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
Background The orally available gold complex auranofin (AF) has been used in humans, primarily as an antirheumatic/immunomodulatory agent. It has been safely administered to healthy dogs to establish pharmacokinetic parameters for oral administration
Publikováno v:
Journal of Clinical and Translational Science
OBJECTIVES/SPECIFIC AIMS: Determine PTL’s mechanism(s) of action in a panel of canine hematopoietic cell lines; this will enable us to 1) verify that PTL is working as expected and 2) rationally select combination therapeutics. Characterize the in
Autor:
Barbara J. Rose
Publikováno v:
Brock Education: a Journal of Educational Research and Practice, Vol 27, Iss 1 (2017)
There are many natural links between academic work and activism that can be used for social justice and equity, but remain underdeveloped in higher education. Using the concept of liminality and the inclusion of personal voice that is central in Scho
Publikováno v:
Cancer Chemotherapy and Pharmacology. 67:83-92
Osteosarcoma (OS) remains an incurable and ultimately fatal disease in many patients, and novel forms of therapy are needed. Improved models of OS that more closely mimic human disease would provide more robust information regarding the utility of no