Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Barbara J Davids"'
Autor:
Barbara J Davids, David S Reiner, Shanda R Birkeland, Sarah P Preheim, Michael J Cipriano, Andrew G McArthur, Frances D Gillin
Publikováno v:
PLoS ONE, Vol 1, p e44 (2006)
Since the Giardia lamblia cyst wall is necessary for survival in the environment and host infection, we tested the hypothesis that it contains proteins other than the three known cyst wall proteins. Serial analysis of gene expression during growth an
Externí odkaz:
https://doaj.org/article/2961da6c476e4f1facbd079c6ec13eac
Autor:
Kurt Hanevik, Marcela Ferella, Matej Radunovic, Ching M. Liu, Nina Langeland, Elaine M. Hanson, Staffan G. Svärd, Marvin Fischer, Majid Ghassemian, Jonathan Ang, Lars Eckmann, Christine Le, Barbara J. Davids, Yukiko Miyamoto
Publikováno v:
Infection and immunity, vol 87, iss 6
Giardia lamblia, one of the most common protozoal infections of the human intestine, is an important worldwide cause of diarrheal disease, malabsorption, malnutrition, delayed cognitive development in children, and protracted postinfectious syndromes
Publikováno v:
International Journal for Parasitology. 42:411-419
The NIMA-related serine/threonine kinases (Neks) function in the cell cycle and regulate ciliary and flagellar length. The Giardia lamblia genome encodes 198 Neks, of which 56 are predicted to be active. Here we believe that we report the first funct
Autor:
Petr Hruz, Barbara J. Davids, Yolanda S. Andersen, Staffan G. Svärd, Patricia C.D. Ferreira, Lars Eckmann, Gabriela Jenikova, Noa Tejman-Yarden, Frances D. Gillin, Mattias K. Andersson, Roy Curtiss
Publikováno v:
Vaccine. 29:9529-9537
Giardia lamblia is a leading protozoan cause of diarrheal disease worldwide, yet preventive medical strategies are not available. A crude veterinary vaccine has been licensed for cats and dogs, but no defined human vaccine is available. We tested the
Autor:
Petr Hruz, Yukiko Miyamoto, Diane Smith, Leo V. Arzu, Lars Eckmann, Valery V. Fokin, Carlos A. Valdez, K. Kangas, Peter Upcroft, Yolanda S. Andersen, Jacqueline A. Upcroft, K. Barry Sharpless, Sabrina E. Brown, Barbara J. Davids, Jonathan C. Tripp, Jaroslaw Kalisiak, Frances D. Gillin
Publikováno v:
Journal of Medicinal Chemistry. 52:4038-4053
Infections with the diarrheagenic pathogen, Giardia lamblia, are commonly treated with the 5-nitroimidazole (5-NI) metronidazole (Mz), and yet treatment failures and Mz resistance occur. Using a panel of new 2-ethenyl and 2-ethanyl 5-NI derivatives,
Autor:
Hanna Skarin, Emma Ringqvist, Barbara J. Davids, David S. Reiner, Adrian B. Hehl, J. E. Daniel Palm, Frances D. Gillin, Malin E.-L. Weiland, Staffan G. Svärd, William J. Griffiths, Lars Eckmann
Publikováno v:
Molecular and Biochemical Parasitology. 159:85-91
Giardia lamblia, an important cause of diarrheal disease, resides in the small intestinal lumen in close apposition to epithelial cells. Since the disease mechanisms underlying giardiasis are poorly understood, elucidating the specific interactions o
Publikováno v:
Current Opinion in Microbiology. 10:554-559
To colonize the human small intestine, Giardia lamblia monitors a dynamic environment. Trophozoites attach to enterocytes that mature and die. The parasites must 'decide' whether to re-attach or differentiate into cysts that survive in the environmen
Autor:
David S. Reiner, Scott C. Dawson, Hilary G. Morrison, Anjali Prabhu, Heidi G. Elmendorf, Ulandt Kim, Mitchell L. Sogin, Adrian B. Hehl, Claudia I. Reich, Erica Lasek-Nesselquist, Rodney D. Adam, Michael Holder, Gerard Manning, Susan M. Huse, Michael J. Cipriano, Feng Chen, Staffan G. Svärd, Nora Q.E. Passamaneck, Anuranjini Nigam, John Samuelson, Aaron A. Best, W. Zacheus Cande, Stephen B. Aley, Daniel Palm, Barbara J. Davids, Frances D. Gillin, Gary J. Olsen, Julie E. J. Nixon, Andrew G. McArthur
Publikováno v:
Science. 317:1921-1926
The genome of the eukaryotic protist Giardia lamblia, an important human intestinal parasite, is compact in structure and content, contains few introns or mitochondrial relics, and has simplified machinery for DNA replication, transcription, RNA proc
Autor:
Finn-Eirik Johansen, Martin G. Martin, Frances D. Gillin, Yolanda S. Andersen, Barbara J. Davids, Michael P. Housley, Jennifer R. Smith, Lars Eckmann, J. E. Daniel Palm, Barbara A. Hendrickson, Staffan G. Svärd
Publikováno v:
The Journal of Immunology. 177:6281-6290
The polymeric Ig receptor (pIgR) is conserved in mammals and has an avian homologue, suggesting evolutionarily important functions in vertebrates. It transports multimeric IgA and IgM across polarized epithelia and is highly expressed in the intestin
Autor:
Malin E.-L. Weiland, Frances D. Gillin, Shanda R. Birkeland, Sarah E. Pacocha, Michael J. Cipriano, Jadwiga Winiecka-Krusnell, Andrew G. McArthur, Barbara J. Davids, Staffan G. Svärd, Daniel Palm, Ewert Linder
Publikováno v:
Molecular and Biochemical Parasitology. 141:199-207
Giardia lamblia is a protozoan parasite infecting the upper mammalian small intestine. Infection relies upon the ability of the parasite to attach to the intestine via a unique cytoskeletal organelle, the ventral disk. We determined the composition a