Efficacy of an adenovirus-vectored foot-and-mouth disease virus serotype A subunit vaccine in cattle using a direct contact transmission model

Autor: John G. Neilan, Christopher Schutta, José Barrera, Melia Pisano, Laszlo Zsak, Ethan Hartwig, Max V. Rasmussen, Barbara J. Kamicker, Damodar Ettyreddy, Douglas E. Brough, Bryan T. Butman, David A. Brake

Publikováno v: BMC Veterinary Research, Vol 14, Iss 1, Pp 1-9 (2018)

Abstract Background A direct contact transmission challenge model was used to simulate natural foot-and-mouth disease virus (FMDV) spread from FMDV A24/Cruzeiro/BRA/55 infected ‘seeder’ steers to naïve or vaccinated steers previously immunized w

Externí odkaz: https://doaj.org/article/d44e40a861c547708a6f63307b3c82ea

An improved, rapid competitive ELISA using a novel conserved 3B epitope for the detection of serum antibodies to foot-and-mouth disease virus

Autor: Juan M. Pacheco, Elizabeth Rieder, Carey L. Bandaranayaka-Mudiyanselage, Mangkey A. Bounpheng, Alfonso Clavijo, Barbara J. Kamicker, David A. Brake, Brooke A. Dancho, Chungwon J. Chung, Sabena Uddowla, Stephen S. Lee, Abu Sayed, Ian C. Olesen, Devendra K. Rai

Publikováno v: Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc

The highly contagious foot-and-mouth disease virus (FMDV) afflicts cloven-hoofed animals, resulting in significant costs because of loss of trade and recovery from disease. We developed a sensitive, specific, and rapid competitive ELISA (cELISA) to d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b31e708c92e0457e17dfa2b8e18c2ea5
https://doi.org/10.1177/1040638718779641

Multiple efficacy studies of an adenovirus-vectored foot-and-mouth disease virus serotype A24 subunit vaccine in cattle using homologous challenge

Autor: Barbara J. Kamicker, Gregory A. Mayr, David A. Brake, Mauro P. Moraes, Laszlo Zsak, Damodar Ettyreddy, Christopher Schutta, Douglas E. Brough, Marvin J. Grubman, Bryan T. Butman, Melia Pisano, John G. Neilan, José Barrera

Publikováno v: Vaccine. 34:3214-3220

The safety and efficacy of an experimental, replication-deficient, human adenovirus-vectored foot-and-mouth disease virus (FMDV) serotype A24 Cruzeiro capsid-based subunit vaccine (AdtA24) was examined in eight independent cattle studies. AdtA24 non-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0f2f1b27d3239a25e83b4fe4903c486
https://doi.org/10.1016/j.vaccine.2015.12.018

Use of ENABL® adjuvant to increase the potency of an adenovirus-vectored foot-and-mouth disease virus serotype A subunit vaccine

Autor: Douglas E. Brough, Marvin J. Grubman, John G. Neilan, Bryan T. Butman, José Barrera, Barbara J. Kamicker, David A. Brake, Melia Pisano, Damodar Ettyreddy, Christopher Schutta, Femi Olutunmbi, Timothy J. Miller

Publikováno v: Vaccine. 36(8)

A foot-and-mouth disease (FMD) recombinant subunit vaccine formulated with a lipid/polymer adjuvant was evaluated in two vaccine efficacy challenge studies in steers. The vaccine active ingredient is a replication-deficient human adenovirus serotype

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b90b7b1b4246a4fd6e5ac3cb2120391
https://pubmed.ncbi.nlm.nih.gov/29358056

Cyclic homopentapeptides 1. Analogs of tuberactinomycins and capreomycin with activity against vancomycin-resistant enterococci and Pasteurella

Autor: Steven M. Finegan, Shigeru F. Hayashi, Arthur E. Girard, J. C. Kane, R.Y. Chandrasekaran, S. A. Kaufman, N. C. Birsner, J.W. Petitpas, B.V. Yang, David A. Whipple, J.P. Lyssikatos, Catherine P. Reese, C.P. MacLelland, Barbara J. Kamicker, B. J. Cronin, S. A. Miller, Joanna Clancy, Susan A. Froshauer, Magee Thomas Victor, B. P. Dirlam, M. A. Lemay, John P. Dirlam, Scott B. Seibel, Wei-Guo Su, Linde Robert Gerald, R. R. Brooks, A. M. Belton, Mark A. Massa, K. T. Sweeney, Martha L. Minich, R. J. Howe, David Austen Perry, Shang-Poa Chang, Nicole L. Kolosko

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 7:1139-1144

A 6a-(3′,4′-dichlorophenylamino) analog of viomycin was uncovered by a high-throughput screen against the animal health pathogen Pasteurella haemolytica, and has served as a novel lead structure for our infectious disease programs. We report here

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c35767df2d0f2186d70412a3ef308451
https://doi.org/10.1016/s0960-894x(97)00186-8