Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Barbara Ingold"'
Autor:
Sefer Elezkurtaj, Selina Greuel, Jana Ihlow, Edward Georg Michaelis, Philip Bischoff, Catarina Alisa Kunze, Bruno Valentin Sinn, Manuela Gerhold, Kathrin Hauptmann, Barbara Ingold-Heppner, Florian Miller, Hermann Herbst, Victor Max Corman, Hubert Martin, Helena Radbruch, Frank L. Heppner, David Horst
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Infection by the new corona virus strain SARS-CoV-2 and its related syndrome COVID-19 has been associated with more than two million deaths worldwide. Patients of higher age and with preexisting chronic health conditions are at an increased
Externí odkaz:
https://doaj.org/article/87b08c6236304a3d8e02d2752ab143b8
Autor:
Nolan Priedigkeit, Kai Ding, William Horne, Jay K. Kolls, Tian Du, Peter C. Lucas, Jens-Uwe Blohmer, Carsten Denkert, Anna Machleidt, Barbara Ingold-Heppner, Steffi Oesterreich, Adrian V. Lee
Publikováno v:
Breast Cancer Research, Vol 23, Iss 1, Pp 1-14 (2021)
Abstract Background Endocrine therapy resistance is a hallmark of advanced estrogen receptor (ER)-positive breast cancer. In this study, we aimed to determine acquired genomic changes in endocrine-resistant disease. Methods We performed DNA/RNA hybri
Externí odkaz:
https://doaj.org/article/8c263986a9324a718707574875504a29
Autor:
Elena Laakmann, Isabell Witzel, Peter A. Fasching, Mahdi Rezai, Christian Schem, Christine Solbach, Hans Tesch, Peter Klare, Andreas Schneeweiss, Christoph Salat, Dirk-Michael Zahm, Jens-Uwe Blohmer, Barbara Ingold-Heppner, Jens Huober, Claus Hanusch, Christian Jackisch, Mattea Reinisch, Michael Untch, Gunter von Minckwitz, Valentina Nekljudova, Volkmar Müller, Sibylle Loibl
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-8 (2019)
Abstract Background The incidence of central nervous system (CNS) metastases in breast cancer patients is rising and has become a major clinical challenge. Only few data are published concerning risk factors for the development of CNS metastases as a
Externí odkaz:
https://doaj.org/article/917ee11fdd924b59b741e34137515454
Autor:
Paul Jank, Claire Gehlhaar, Bianca Lederer, Caterina Fontanella, Andreas Schneeweiss, Thomas Karn, Frederik Marmé, Hans-Peter Sinn, Marion van Mackelenbergh, Bruno Sinn, Dirk-Michael Zahm, Barbara Ingold-Heppner, Christian Schem, Elmar Stickeler, Peter A Fasching, Valentina Nekljudova, Eliane Tabea Taube, Frank Heppner, Volkmar Müller, Carsten Denkert, Sibylle Loibl
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257142 (2021)
[This corrects the article DOI: 10.1371/journal.pone.0238021.].
Externí odkaz:
https://doaj.org/article/8aca656624204da98cdb0cb958334577
Autor:
Paul Jank, Claire Gehlhaar, Lederer Bianca, Fontanella Caterina, Schneeweiss Andreas, Thomas Karn, Frederik Marmé, Hans-Peter Sinn, Marion van Mackelenbergh, Bruno Sinn, Dirk-Michael Zahm, Barbara Ingold-Heppner, Christian Schem, Elmar Stickeler, Peter A Fasching, Valentina Nekljudova, Eliane Tabea Taube, Frank Heppner, Volkmar Müller, Carsten Denkert, Sibylle Loibl
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0238021 (2020)
Triple-negative breast cancer (TNBC) is typically treated with chemotherapeutic agents, including carboplatin (Cb), an DNA platinating agent. The O6-methylguanine-DNA-methyltransferase gene (MGMT) encodes for the protein O6-alkylguanine-DNA-alkyltran
Externí odkaz:
https://doaj.org/article/57023619e9d140768d447fde0e25eade
Autor:
Bettina Schreiner, Elisa Romanelli, Pawel Liberski, Barbara Ingold-Heppner, Bettina Sobottka-Brillout, Tom Hartwig, Vijay Chandrasekar, Helge Johannssen, Hanns Ulrich Zeilhofer, Adriano Aguzzi, Frank Heppner, Martin Kerschensteiner, Burkhard Becher
Publikováno v:
Cell Reports, Vol 12, Iss 9, Pp 1377-1384 (2015)
Although the importance of reactive astrocytes during CNS pathology is well established, the function of astroglia in adult CNS homeostasis is less well understood. With the use of conditional, astrocyte-restricted protein synthesis termination, we f
Externí odkaz:
https://doaj.org/article/7fd4a84eb2e94f8bbb87b77ec166f8a4
Autor:
Gunther Boysen, Damaris Bausch-Fluck, Claudio R. Thoma, Anna M. Nowicka, Daniel P. Stiehl, Igor Cima, Van-Duc Luu, Adriana von Teichman, Thomas Hermanns, Tullio Sulser, Barbara Ingold-Heppner, Niklaus Fankhauser, Roland H. Wenger, Wilhelm Krek, Peter Krek, Bernd Wollscheid, Holger Moch
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 6, Pp 535-546 (2012)
Externí odkaz:
https://doaj.org/article/e15cb2f3daa24e03aafef3f77d37c240
Autor:
Bettina Schreiner, Barbara Ingold-Heppner, Debora Pehl, Giuseppe Locatelli, Helia Berrit-Schönthaler, Burkhard Becher
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120454 (2015)
Oligodendrocytes, the myelin-forming glial cells of the central nervous system (CNS), are fundamental players in rapid impulse conduction and normal axonal functions. JunB and c-Jun are DNA-binding components of the AP-1 transcription factor, which i
Externí odkaz:
https://doaj.org/article/2ff5f555a7574d5fa7f5b25bf7ec44c3
Autor:
Barbara Ingold, Eva Simon, Ute Ungethüm, Ralf-Jürgen Kuban, Berit M Müller, Amelie Lupp, Ulf Neumann, Matthias P A Ebert, Carsten Denkert, Wilko Weichert, Stefan Schulz, Christoph Röcken
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10087 (2010)
BACKGROUND: G-protein-coupled receptors (GPCRs) are prime candidates for novel cancer prevention and treatment strategies. We searched for differentially expressed GPCRs in node positive gastric carcinomas. METHODOLOGY/PRINCIPAL FINDINGS: Differentia
Externí odkaz:
https://doaj.org/article/c27f9da7364b45d08f86220941190059
Publikováno v:
PLoS ONE, Vol 4, Iss 3, p e4775 (2009)
The O(6)-methylguanine-methyltransferase (MGMT) promoter methylation status is a predictive parameter for the response of malignant gliomas to alkylating agents such as temozolomide. First clinical reports on treating brain metastases with temozolomi
Externí odkaz:
https://doaj.org/article/24a7b4921bc04836af700509691f9b79