Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Barbara Hopkins"'
Autor:
Barbara Hopkins, Steve Kitchen, Joost J. van Veen, Alex Stephenson-Brown, Zunaid Chunara, Susan Guy
Publikováno v:
International Journal of Laboratory Hematology. 44:399-406
Introduction The Summary of Product Characteristics for the direct thrombin inhibitor argatroban states monitoring should be by activated partial thromboplastin time (APTT), with a target range of 1.5-3.0 times the patients' baseline APTT. APTT may b
Autor:
Shwetal Mehta, An-Chi Tien, Sonam Patel, Tigran Margaryan, Anilkumar Thaghalli Shivanna, Leonel Elena, Jennifer Molloy, William Knight, Ruiheng Hon, Mackenna Elliott, Mariya Stavnichuk, Zorana Opachich, Yu-Wei Chang, Chelsea Montgomery, Sarah Himes, Barbara Hopkins, Artak Tovmasyan, Nader Sanai
Publikováno v:
Cancer Research. 83:2796-2796
WEE1 kinase regulates G2/M checkpoint transition via phosphorylation of CDK1 and prevents entry into mitosis. WEE1 inhibition increases genomic instability due to G2/M checkpoint inactivation and can result in mitotic catastrophe as monotherapy or wh
Autor:
Annette Bowyer, Paula Brown, Barbara Hopkins, Marie Scully, Fiona Shepherd, Anna Lowe, Patrick Mensah, Rhona Maclean, Steve Kitchen, Joost J. Veen
Publikováno v:
British journal of haematologyREFERENCES. 197(3)
Acquired immune thrombotic thrombocytopenic purpura (iTTP) is a rare disease with a poor prognosis if undiagnosed. It is caused by autoantibody production to the von Willebrand factor (VWF) cleaving protease, A disintegrin and metalloproteinase with
Autor:
Shwetal Mehta, Jun Jiang, Barbara Hopkins, Jing Li, Artak Tovmasyan, Garry Hook, Nader Sanai, Ernesto Luna Melendez
Publikováno v:
Neuro Oncol
BACKGROUND Lysine specific demethylase 1 (LSD1) is a histone demethylase implicated in the maintenance of pluripotency and proliferation gene programs that give rise to a number of cancers. SP-2577 is a first-in-class selective and reversible inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aca58d7c0b3ed833f38ac89674e7239
https://europepmc.org/articles/PMC8598443/
https://europepmc.org/articles/PMC8598443/
Autor:
Carola Neumann, Shireen Attaran, John Skoko, Barbara Hopkins, Megan Wright, Alp Asan, Hyun Ae Woo, Laurel Wood, Adam Feinberg
Publikováno v:
Free Radical Biology and Medicine. 180:s36
Autor:
An-Chi Tien, Miao Liu, Chelsea Pennington-Krygier, Nader Sanai, Mackenna Elliott, Yu-Wei Chang, Shwetal Mehta, Michael Holter, Tigran Margaryan, Connor White, Jennifer Molloy, William Knight, Barbara Hopkins, Artak Tovmasyan, Ernesto Luna Melendez, Sarah Himes
Publikováno v:
Neuro-Oncology. 23:vi165-vi165
Cell-cycle deregulation is at the crux of all malignancies, including glioblastoma (GBM). Aurora Kinase A (AURKA) plays a central role in G2/M transition and faithful chromosome segregation. In this study, we evaluated the pharmacokinetics, pharmacod
Autor:
Kumaravel Rajakumar, Vijay Ganji, Flora Olabopo, Ruiyan Luo, Michael F. Holick, Anita M. Nucci, Caitlin Sundby Russell, Barbara Hopkins
Publikováno v:
Dermato-endocrinology
Previous studies have found a high prevalence of vitamin D deficiency in children, yet few validated dietary vitamin D assessment tools are available for use in children. Our objective was to determine whether a short food frequency questionnaire (SF
Autor:
David B. Richardson, Steve Wing, Karin Yeatts, Christopher D. Heaney, Robert L. Campbell, Barbara Hopkins, David Caldwell
Publikováno v:
Environmental Research. 111:847-852
Municipal solid waste landfills are sources of air pollution that may affect the health and quality of life of neighboring communities.To investigate health and quality of life concerns of neighbors related to landfill air pollution.Landfill neighbor
Publikováno v:
Journal of Health Care for the Poor and Underserved. 16:111-126
Focus groups were used to gain insight into the nutrition-related attitudes and motivations of overweight African-American adolescents and young adults enrolled in the Atlanta Job Corps Center in preparation for designing an effective and culturally
Publikováno v:
Epidemiology. 11:427-433
We examined the association of exposure to environmental tobacco smoke with birth weight and gestational age in a large, prospective study. We also compared these endpoints between infants of active maternal smokers and those of non-smoking, non-ETS