Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Barbara Hebeis"'
Publikováno v:
Biochemical Society Transactions. 32:789-791
PI3K (phosphoinositide 3-kinase) IA family members contain a regulatory subunit and a catalytic subunit. The p110δ catalytic subunit is expressed predominantly in haematopoietic cells. There, among other functions, it regulates antigen receptor-medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8440f89613f596a4ff1576197b32a840
https://doi.org/10.1042/bst0320789
https://doi.org/10.1042/bst0320789
Autor:
Klaus Okkenhaug, Sara Santinelli, Nigel Killeen, Julia Rolf, Dorottya Kövesdi, Michelle L. Janas, Dalya R. Soond, Louise M. C. Webb, Martin R Turner, Barbara Hebeis, Ted Saunders, Sarah Bell
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 185(7)
The generation of high-affinity Abs is essential for immunity and requires collaboration between B and T cells within germinal centers (GCs). By using novel mouse models with a conditional deletion of the p110δ catalytic subunit of the PI3K pathway,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f717ca186f3e723d1181eaae687e8f4
https://pubmed.ncbi.nlm.nih.gov/20826752
https://pubmed.ncbi.nlm.nih.gov/20826752
Autor:
Andrew N. J. McKenzie, Simon McAdam, Sarah Bell, Martin R Turner, Barbara Hebeis, Piers C. Emson, Helen Reynolds, Elena Vigorito
Publikováno v:
Molecular and cellular biology. 24(2)
RhoG is a low-molecular-weight GTPase highly expressed in lymphocytes that activates gene transcription and promotes cytoskeletal reorganization in vitro. To study the in vivo function of RhoG, we generated mice homozygous for a targeted disruption o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c32bcd43e71e950eb650922183eed136
https://pubmed.ncbi.nlm.nih.gov/14701744
https://pubmed.ncbi.nlm.nih.gov/14701744