Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Barbara Guisan"'
Autor:
Françoise Roch-Ramel, Barbara Guisan
Publikováno v:
Physiology. 14:80-84
The theory of the “four-component model” of urate excretion in humans is reevaluated, considering that a decrease in urate excretion induced by drugs like pyrazinamide or by endogenous compounds like lactate and ketone bodies might be a result of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14974b4dc78cd6dbd69a63290f5225a1
https://doi.org/10.1152/physiologyonline.1999.14.2.80
https://doi.org/10.1152/physiologyonline.1999.14.2.80
Publikováno v:
Cellular Physiology and Biochemistry. 6:60-71
Earlier studies demonstrated that an apical anion exchanger which accepts urate, chloride, aliphatic monocarboxylates, and the aromatic anions, pyrazinoate (PZA) and nicotinate, plays a major role in urate reabsorption in human proximal tubules. In s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15099f696e6dd308db53c45785c45687
https://doi.org/10.1159/000154795
https://doi.org/10.1159/000154795
Publikováno v:
The American journal of physiology. 270(1 Pt 2)
[14C]urate and p-[14C]aminohippurate (PAH) uptake by human brush-border membrane vesicles (BBMV) were measured in the presence of an inwardly oriented sodium gradient. No direct sodium cotransport was observed. Indirect [14C]urate coupling to sodium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::996dd1c783706bf6cc8262ab95476543
https://pubmed.ncbi.nlm.nih.gov/8769823
https://pubmed.ncbi.nlm.nih.gov/8769823
Publikováno v:
The American journal of physiology. 266(5 Pt 2)
Mechanisms of urate transport were investigated in human renal brush-border membrane vesicles. The imposition of an outwardly directed Cl- gradient, in voltage-clamp and pH-clamp conditions, stimulated [14C]urate uptake. Organic anions, including pyr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e62f846cc32d173f78943e795b43d0
https://pubmed.ncbi.nlm.nih.gov/8203564
https://pubmed.ncbi.nlm.nih.gov/8203564
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781489926401
Urate is transported bidirectionally by the renal proximal tubule of mammals. The direction of the net flux is, however, highly species dependent, so that some mammals are urate “reabsorbers” while others are urate “secreters” (Roch-Ramel and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d866d132248e40e11e143cb2de866253
https://doi.org/10.1007/978-1-4899-2638-8_40
https://doi.org/10.1007/978-1-4899-2638-8_40
Autor:
oise, Roch-Ramel Fran, Barbara, Guisan
Publikováno v:
News in Physiological Sciences; April 1999, Vol. 14 Issue: 2 p80-84, 5p