Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Barbara Gonzalez Teran"'
Autor:
Rafael Romero-Becerra, Alfonso Mora, Elisa Manieri, Ivana Nikolic, Ayelén Melina Santamans, Valle Montalvo-Romeral, Francisco Miguel Cruz, Elena Rodríguez, Marta León, Luis Leiva-Vega, Laura Sanz, Víctor Bondía, David Filgueiras-Rama, Luis Jesús Jiménez-Borreguero, José Jalife, Barbara Gonzalez-Teran, Guadalupe Sabio
Publikováno v:
eLife, Vol 11 (2022)
Stress-activated p38 kinases control a plethora of functions, and their dysregulation has been linked to the development of steatosis, obesity, immune disorders, and cancer. Therefore, they have been identified as potential targets for novel therapeu
Externí odkaz:
https://doaj.org/article/5fb94dd9292040efb96bdc1f5880f2fb
Autor:
María Crespo, Barbara Gonzalez-Teran, Ivana Nikolic, Alfonso Mora, Cintia Folgueira, Elena Rodríguez, Luis Leiva-Vega, Aránzazu Pintor-Chocano, Macarena Fernández-Chacón, Irene Ruiz-Garrido, Beatriz Cicuéndez, Antonia Tomás-Loba, Noelia A-Gonzalez, Ainoa Caballero-Molano, Daniel Beiroa, Lourdes Hernández-Cosido, Jorge L Torres, Norman J Kennedy, Roger J Davis, Rui Benedito, Miguel Marcos, Ruben Nogueiras, Andrés Hidalgo, Nuria Matesanz, Magdalena Leiva, Guadalupe Sabio
Publikováno v:
eLife, Vol 9 (2020)
Liver metabolism follows diurnal fluctuations through the modulation of molecular clock genes. Disruption of this molecular clock can result in metabolic disease but its potential regulation by immune cells remains unexplored. Here, we demonstrated t
Externí odkaz:
https://doaj.org/article/68531b33dacf4efb84a24e972b0693bf
Autor:
Lili Zhu, Krishna Choudhary, Barbara Gonzalez-Teran, Yen-Sin Ang, Reuben Thomas, Nicole R. Stone, Lei Liu, Ping Zhou, Chenchen Zhu, Hongmei Ruan, Yu Huang, Shibo Jin, Angelo Pelonero, Frances Koback, Arun Padmanabhan, Nandhini Sadagopan, Austin Hsu, Mauro W. Costa, Casey A. Gifford, Joke G. van Bemmel, Ruth Hüttenhain, Vasanth Vedantham, Bruce R. Conklin, Brian L. Black, Benoit G. Bruneau, Lars Steinmetz, Nevan J. Krogan, Katherine S. Pollard, Deepak Srivastava
Publikováno v:
Circulation. 146(10)
Background: GATA4 (GATA-binding protein 4), a zinc finger–containing, DNA-binding transcription factor, is essential for normal cardiac development and homeostasis in mice and humans, and mutations in this gene have been reported in human heart def
Autor:
Michael Alexanian, Arun Padmanabhan, Tomohiro Nishino, Joshua G. Travers, Lin Ye, Clara Youngna Lee, Nandhini Sadagopan, Yu Huang, Angelo Pelonero, Kirsten Auclair, Ada Zhu, Barbara Gonzalez Teran, Will Flanigan, Charis Kee-Seon Kim, Koya Lumbao-Conradson, Mauro Costa, Rajan Jain, Israel Charo, Saptarsi M. Haldar, Katherine S. Pollard, Ronald J. Vagnozzi, Timothy A. McKinsey, Pawel F. Przytycki, Deepak Srivastava
Chronic inflammation and tissue fibrosis are common stress responses that worsen organ function, yet the molecular mechanisms governing their crosstalk are poorly understood. In diseased organs, stress-induced changes in gene expression fuel maladapt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce3f813f15b68d411cced6b1ab15fc02
https://doi.org/10.1101/2023.01.06.522937
https://doi.org/10.1101/2023.01.06.522937
Autor:
Sanjeev S. Ranade, Sean Whalen, Ivana Zlatanova, Tomohiro Nishino, Benjamin van Soldt, Lin Ye, Angelo Pelonero, Langley Grace Wallace, Yu Huang, Michael Alexanian, Arun Padmanabhan, Barbara Gonzalez-Teran, Pawel Przytycki, Mauro W. Costa, Casey A. Gifford, Brian L. Black, Katherine S. Pollard, Deepak Srivastava
Communication between myriad cell types during organ formation underlies proper morphogenesis1. In cardiac development, reciprocal signaling between mesoderm progenitors and neural crest cells is essential, and its disruption leads to congenital hear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::643e949c5df7fd1acbf53c7827855649
https://doi.org/10.1101/2022.07.25.501458
https://doi.org/10.1101/2022.07.25.501458
Autor:
Rafael Romero-Becerra, Alfonso Mora, Elisa Manieri, Ivana Nikolic, Ayelén Melina Santamans, Valle Montalvo-Romeral, Francisco Miguel Cruz, Elena Rodríguez, Marta León, Luis Leiva-Vega, Laura Sanz, Víctor Bondía, David Filgueiras-Rama, Luis Jesús Jiménez-Borreguero, José Jalife, Barbara Gonzalez-Teran, Guadalupe Sabio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::163ab446ce5c2058a56072dea76084d9
https://doi.org/10.7554/elife.75250.sa2
https://doi.org/10.7554/elife.75250.sa2
Autor:
Barbara Gonzalez-Teran, Maureen Pittman, Franco Felix, Reuben Thomas, Desmond Richmond-Buccola, Ruth Hüttenhain, Krishna Choudhary, Elisabetta Moroni, Mauro W. Costa, Yu Huang, Arun Padmanabhan, Michael Alexanian, Clara Youngna Lee, Bonnie E.J. Maven, Kaitlen Samse-Knapp, Sarah U. Morton, Michael McGregor, Casey A. Gifford, J.G. Seidman, Christine E. Seidman, Bruce D. Gelb, Giorgio Colombo, Bruce R. Conklin, Brian L. Black, Benoit G. Bruneau, Nevan J. Krogan, Katherine S. Pollard, Deepak Srivastava
Publikováno v:
Cell, vol 185, iss 5
Cell
Cell (Cambridge) 185 (2022): 794–814.e30. doi:10.1016/j.cell.2022.01.021
info:cnr-pdr/source/autori:Gonzalez-Teran B.; Pittman M.; Felix F.; Thomas R.; Richmond-Buccola D.; Huttenhain R.; Choudhary K.; Moroni E.; Costa M.W.; Huang Y.; Padmanabhan A.; Alexanian M.; Lee C.Y.; Maven B.E.J.; Samse-Knapp K.; Morton S.U.; McGregor M.; Gifford C.A.; Seidman J.G.; Seidman C.E.; Gelb B.D.; Colombo G.; Conklin B.R.; Black B.L.; Bruneau B.G.; Krogan N.J.; Pollard K.S.; Srivastava D./titolo:Transcription factor protein interactomes reveal genetic determinants in heart disease/doi:10.1016%2Fj.cell.2022.01.021/rivista:Cell (Cambridge)/anno:2022/pagina_da:794/pagina_a:814.e30/intervallo_pagine:794–814.e30/volume:185
Cell
Cell (Cambridge) 185 (2022): 794–814.e30. doi:10.1016/j.cell.2022.01.021
info:cnr-pdr/source/autori:Gonzalez-Teran B.; Pittman M.; Felix F.; Thomas R.; Richmond-Buccola D.; Huttenhain R.; Choudhary K.; Moroni E.; Costa M.W.; Huang Y.; Padmanabhan A.; Alexanian M.; Lee C.Y.; Maven B.E.J.; Samse-Knapp K.; Morton S.U.; McGregor M.; Gifford C.A.; Seidman J.G.; Seidman C.E.; Gelb B.D.; Colombo G.; Conklin B.R.; Black B.L.; Bruneau B.G.; Krogan N.J.; Pollard K.S.; Srivastava D./titolo:Transcription factor protein interactomes reveal genetic determinants in heart disease/doi:10.1016%2Fj.cell.2022.01.021/rivista:Cell (Cambridge)/anno:2022/pagina_da:794/pagina_a:814.e30/intervallo_pagine:794–814.e30/volume:185
Congenital heart disease (CHD) is present in 1% of live births, yet identification of causal mutations remains challenging. We hypothesized that genetic determinants for CHDs may lie in the protein interactomes of transcription factors whose mutation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bcdf4435eb5987a378294012ffb20d0
https://escholarship.org/uc/item/00m1b8f0
https://escholarship.org/uc/item/00m1b8f0
Autor:
Barbara Gonzalez Teran, Maureen Pittman, Reuben Thomas, Franco Felix, Desmond Richmond-Buccola, Krishna Choudhary, Elisabetta Moroni, Colombo Giorgio, Arun Padmanabhan, Mauro Costa, Yu Huang, Michael Alexanian, Clara Lee, Bonie Cole, Kaitlen Samse-Knapp, Michael McGregor, Casey Gifford, Ruth Huttenhain, Bruce Gelb, Bruce Conklin, Brian L Black, Benoit Bruneau, Nevan Krogan, Katherine Pollard, Deepak Srivastava
Publikováno v:
Circulation, vol 144, iss Suppl_1
Congenital heart disease (CHD) is present in 1% of live births, yet despite large-scale genomic sequencing efforts, identification of causal mutations remains a challenge. We hypothesized that genetic determinants for CHDs may lie in the protein inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da2adc3f664c2fdd53e234c26c9b7c74
https://escholarship.org/uc/item/2pq493zw
https://escholarship.org/uc/item/2pq493zw
Autor:
Rafael Romero-Becerra, Alfonso Mora, Elisa Manieri, Ivana Nikolic, Ayelén Melina Santamans, Valle Montalvo-Romeral, Francisco Miguel Cruz, Elena Rodríguez, Marta León, Luis Leiva-Vega, Laura Sanz, Víctor Bondía, David Filgueiras-Rama, Luis Jesús Jiménez-Borreguero, José Jalife, Barbara Gonzalez-Teran, Guadalupe Sabio
Publikováno v:
eLife. 11
Stress-activated p38 kinases control a plethora of functions, and their dysregulation has been linked to the development of steatosis, obesity, immune disorders, and cancer. Therefore, they have been identified as potential targets for novel therapeu
Autor:
Arun Padmanabhan, Katherine S. Pollard, Joshua G. Travers, Ricardo Linares-Saldana, Kathryn N. Ivey, Pawel F. Przytycki, Jin Yang, Michael G. Rosenfeld, Barbara Gonzalez Teran, Franco Felix, Gaia Andreoletti, Qiming Duan, Deepak Srivastava, Michael Alexanian, Rudi Micheletti, Sanjeev S. Ranade, Saptarsi M. Haldar, Lin Ye, Yu Huang, Casey A. Gifford, Rajan Jain, Timothy A. McKinsey
In diseased organs, stress-activated signaling cascades alter chromatin, triggering broad shifts in transcription and cell state that exacerbate pathology. Fibroblast activation is a common stress response that worsens lung, liver, kidney and heart d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f822752ed23f4eccecada4498b5950e0
https://doi.org/10.1101/2020.07.21.214874
https://doi.org/10.1101/2020.07.21.214874