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of 147
pro vyhledávání: '"Barbara G Klupp"'
Autor:
Jonas L Delva, Cliff Van Waesberghe, Barbara G Klupp, Thomas C Mettenleiter, Herman W Favoreel
Publikováno v:
PLoS Pathogens, Vol 17, Iss 11, p e1010117 (2021)
Plasmacytoid dendritic cells (pDC) are important innate immune cells during the onset of viral infections as they are specialized in the production of massive amounts of antiviral type I interferon (IFN). Alphaherpesviruses such as herpes simplex vir
Externí odkaz:
https://doaj.org/article/0d1ceb4dee1a43358afdc2d1d5a78d7c
Autor:
Julia Sehl, Julia E Hölper, Barbara G Klupp, Christina Baumbach, Jens P Teifke, Thomas C Mettenleiter
Publikováno v:
PLoS Pathogens, Vol 16, Iss 3, p e1008445 (2020)
Herpesviral encephalitis caused by Herpes Simplex Virus 1 (HSV-1) is one of the most devastating diseases in humans. Patients present with fever, mental status changes or seizures and when untreated, sequelae can be fatal. Herpes Simplex Encephalitis
Externí odkaz:
https://doaj.org/article/8ccc7303e5cc4f27bee87caa1a8e041b
Autor:
Martin Zühlsdorf, Sebastiaan Werten, Barbara G Klupp, Gottfried J Palm, Thomas C Mettenleiter, Winfried Hinrichs
Publikováno v:
PLoS Pathogens, Vol 12, Iss 3, p e1005506 (2016)
Externí odkaz:
https://doaj.org/article/911a41ade263495e955729ca69ed91af
Autor:
Martin Zühlsdorf, Sebastiaan Werten, Barbara G Klupp, Gottfried J Palm, Thomas C Mettenleiter, Winfried Hinrichs
Publikováno v:
PLoS Pathogens, Vol 11, Iss 7, p e1005045 (2015)
Herpesviruses encode a characteristic serine protease with a unique fold and an active site that comprises the unusual triad Ser-His-His. The protease is essential for viral replication and as such constitutes a promising drug target. In solution, a
Externí odkaz:
https://doaj.org/article/559a22dcd7a341b7b6cb95e4d23c6e81
Autor:
Melina Vallbracht, Marina Schnell, Annemarie Seyfarth, Walter Fuchs, Richard Küchler, Thomas C. Mettenleiter, Barbara G. Klupp
Publikováno v:
Viruses, Vol 16, Iss 1, p 26 (2023)
Herpesvirus entry requires the coordinated action of at least four viral glycoproteins. Virus-specific binding to a cellular receptor triggers a membrane fusion cascade involving the conserved gH/gL complex and gB. Although gB is the genuine herpesvi
Externí odkaz:
https://doaj.org/article/db941c5b57c64ae6b5746da12985bf49
Publikováno v:
Viruses, Vol 15, Iss 6, p 1283 (2023)
African swine fever is a viral disease of swine caused by the African swine fever virus (ASFV). Currently, ASFV is spreading over the Eurasian continent and threatening global pig husbandry. One viral strategy to undermine an efficient host cell resp
Externí odkaz:
https://doaj.org/article/087481cfb3dd42dda7d64319767ec45e
Publikováno v:
Annual Review of Virology. 10
Nuclear egress of herpesvirus capsids across the intact nuclear envelope is an exceptional vesicle-mediated nucleocytoplasmic translocation resulting in the delivery of mature herpesvirus capsids into the cytosol. Budding of the (nucleo)capsid at and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89bf52c91eb53e94bf1ae01985061cb0
https://doi.org/10.1146/annurev-virology-111821-105518
https://doi.org/10.1146/annurev-virology-111821-105518
Autor:
Barbara G. Klupp
Publikováno v:
Pathogens, Vol 10, Iss 6, p 719 (2021)
Suid alphaherpesvirus 1 (SuHV-1), better known as Pseudorabies virus (PrV), an alphaherpesvirus of swine, is the causative agent of Aujeszky’s Disease [...]
Externí odkaz:
https://doaj.org/article/17ac087dee3d4bd2aa1505ec186bf5e5
Publikováno v:
Pathogens, Vol 10, Iss 1, p 61 (2021)
Envelope glycoprotein (g)B is conserved throughout the Herpesviridae and mediates fusion of the viral envelope with cellular membranes for infectious entry and spread. Like all viral envelope fusion proteins, gB is modified by asparagine (N)-linked g
Externí odkaz:
https://doaj.org/article/8040c6956b7c41c1aa4d8d51e98df6cc
Publikováno v:
Cells, Vol 9, Iss 3, p 738 (2020)
Newly assembled herpesvirus nucleocapsids traverse the intact nuclear envelope by a vesicle-mediated nucleo-cytoplasmic transport for final virion maturation in the cytoplasm. For this, they bud at the inner nuclear membrane resulting in primary enve
Externí odkaz:
https://doaj.org/article/f634f043492841e2a8a12b5b1b350c27