Zobrazeno 1 - 10
of 302
pro vyhledávání: '"Barbara Fazekas"'
Autor:
Thomas V. Guy, Alexandra M. Terry, Helen M. McGuire, Elena Shklovskaya, Barbara Fazekas de St Groth
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
ABSTRACTThere has been growing interest in the role of B cells in antitumour immunity and potential use in adoptive cellular therapies. To date, the success of such therapies is limited. The intrinsic capacity of B cells to specifically activate tumo
Externí odkaz:
https://doaj.org/article/8be77172bb9f42ee9dc1e619473a6d3e
Autor:
Lauren Stern, Helen M. McGuire, Selmir Avdic, Barbara Fazekas de St Groth, David Gottlieb, Allison Abendroth, Emily Blyth, Barry Slobedman
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Human cytomegalovirus is a major cause of morbidity and mortality in transplant patients and multiple immune cells types are critical during infection and reactivation. Here the authors assess the immune cell compartments of haematopoietic stem cell
Externí odkaz:
https://doaj.org/article/c2bb6d2a17434444b3347285848682cd
Autor:
Katharine A Kott, Adam S Chan, Stephen T Vernon, Thomas Hansen, Taiyun Kim, Macha deDreu, Bavani Gunasegaran, Andrew J Murphy, Ellis Patrick, Peter J Psaltis, Stuart M Grieve, Jean Y Yang, Barbara Fazekas de St Groth, Helen M McGuire, Gemma A Figtree
Publikováno v:
Clinical & Translational Immunology, Vol 12, Iss 11, Pp n/a-n/a (2023)
Abstract Objective The importance of inflammation in atherosclerosis is well accepted, but the role of the adaptive immune system is not yet fully understood. To further explore this, we assessed the circulating immune cell profile of patients with c
Externí odkaz:
https://doaj.org/article/c6896394e4c5467bb8255df0f5093c80
Autor:
Kirstine J. Bell, Sonia Saad, Bree J. Tillett, Helen M. McGuire, Sara Bordbar, Yu Anne Yap, Long T. Nguyen, Marc R. Wilkins, Susan Corley, Shannon Brodie, Sussan Duong, Courtney J. Wright, Stephen Twigg, Barbara Fazekas de St Groth, Leonard C. Harrison, Charles R. Mackay, Esteban N. Gurzov, Emma E. Hamilton-Williams, Eliana Mariño
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-21 (2022)
Abstract Background Short-chain fatty acids (SCFAs) produced by the gut microbiota have beneficial anti-inflammatory and gut homeostasis effects and prevent type 1 diabetes (T1D) in mice. Reduced SCFA production indicates a loss of beneficial bacteri
Externí odkaz:
https://doaj.org/article/e25eb74805594ff78c91c45cb9747d55
Autor:
Isabella Batten, Mark W. Robinson, Arthur White, Cathal Walsh, Barbara Fazekas, Jason Wyse, Antonia Buettner, Suzanne D’Arcy, Emily Greenan, Conor C. Murphy, Zoe Wigston, Joan Ní Gabhann-Dromgoole, Edward M. Vital, Mark A. Little, Nollaig M. Bourke
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Type I interferon (IFN) dysregulation is a major contributory factor in the development of several autoimmune diseases, termed type I interferonopathies, and is thought to be the pathogenic link with chronic inflammation in these conditions.
Externí odkaz:
https://doaj.org/article/0b1c1eccbc1e48ba9d209eb9887c08a1
Autor:
Samuel E. Norton, Julia K. H. Leman, Tiffany Khong, Andrew Spencer, Barbara Fazekas de St Groth, Helen M. McGuire, Roslyn A. Kemp
Publikováno v:
BMC Bioinformatics, Vol 21, Iss 1, Pp 1-14 (2020)
Abstract Background The advent of mass cytometry has dramatically increased the parameter limit for immunological analysis. New approaches to analysing high parameter cytometry data have been developed to ease analysis of these complex datasets. Many
Externí odkaz:
https://doaj.org/article/58fe9b4b0d7a4a0ba9e8a36335dbeb85
Autor:
Jayden A. O'Brien, Helen M. McGuire, Diana Shinko, Barbara Fazekas de St Groth, Marc A. Russo, Dominic Bailey, Danielle M. Santarelli, Katie Wynne, Paul J. Austin
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 15, Iss , Pp 100283- (2021)
Diabetic neuropathic pain is a common and devastating complication of type 1 diabetes, but the mechanism by which it develops and persists is yet to be fully elucidated. This study utilised high-dimensional suspension mass cytometry in a pilot cohort
Externí odkaz:
https://doaj.org/article/435fcfc6ded54c1c80ad5ce8e786e538
Autor:
Amber Dorey, Krystyna Cwiklinski, James Rooney, Carolina De Marco Verissimo, Jesús López Corrales, Heather Jewhurst, Barbara Fazekas, Nichola Eliza Davies Calvani, Siobhán Hamon, Siobhán Gaughan, John P. Dalton, Richard Lalor
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Trematode parasites of the genus Fasciola are the cause of liver fluke disease (fasciolosis) in humans and their livestock. Infection of the host involves invasion through the intestinal wall followed by migration in the liver that results in extensi
Externí odkaz:
https://doaj.org/article/54f347db0562435db9ce1c0d052acc5b
Autor:
Marc A. Russo, Nathan T. Fiore, Caryn van Vreden, Dominic Bailey, Danielle M. Santarelli, Helen M. McGuire, Barbara Fazekas de St Groth, Paul J. Austin
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-17 (2019)
Abstract Background Complex regional pain syndrome (CRPS) is a debilitating condition where trauma to a limb results in devastating persistent pain that is disproportionate to the initial injury. The pathophysiology of CRPS remains unknown; however,
Externí odkaz:
https://doaj.org/article/9e92e7613791468c83d05d364be8473d
Autor:
Katharine A. Kott, Stephen T. Vernon, Thomas Hansen, Macha de Dreu, Souvik K. Das, Joseph Powell, Barbara Fazekas de St Groth, Belinda A. Di Bartolo, Helen M. McGuire, Gemma A. Figtree
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 24 (2020)
Abstract Coronary artery disease remains the leading cause of death globally and is a major burden to every health system in the world. There have been significant improvements in risk modification, treatments, and mortality; however, our ability to
Externí odkaz:
https://doaj.org/article/6f57794a0ba843839cf34a7df19ac938