Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Barbara F. Akum"'
Autor:
Ana R. Rodriguez, Erin D. Anderson, Kate M. O’Neill, Przemyslaw P. McEwan, Nicholas F. Vigilante, Munjin Kwon, Barbara F. Akum, Tamara M. Stawicki, David F. Meaney, Bonnie L. Firestein
Publikováno v:
Network Neuroscience, Vol 5, Iss 1, Pp 166-197 (2021)
AbstractCytosolic PSD-95 interactor (cypin) regulates many aspects of neuronal development and function, ranging from dendritogenesis to synaptic protein localization. While it is known that removal of postsynaptic density protein-95 (PSD-95) from th
Externí odkaz:
https://doaj.org/article/1fec7c349a124b99bff18e67c059684b
Autor:
Przemyslaw Swiatkowski, Ina Nikolaeva, Gaurav Kumar, Avery Zucco, Barbara F. Akum, Mihir V. Patel, Gabriella D’Arcangelo, Bonnie L. Firestein
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract Glutamate-induced excitotoxicity, mediated by overstimulation of N-methyl-D-aspartate (NMDA) receptors, is a mechanism that causes secondary damage to neurons. The early phase of injury causes loss of dendritic spines and changes to synaptic
Externí odkaz:
https://doaj.org/article/187734828ebb47e29e21b6060cf27c55
Autor:
Kate M O'Neill, Barbara F Akum, Survandita T Dhawan, Munjin eKwon, Christopher G Langhammer, Bonnie L Firestein
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 9 (2015)
Determining the shape of cell-specific dendritic arbors is a tightly regulated process that occurs during development. When this regulation is aberrant, which occurs during disease or injury, alterations in dendritic shape result in changes to neural
Externí odkaz:
https://doaj.org/article/e0f607e0482946808bb9a08d04b45536
Autor:
Eric S, Sweet, Keith R, Lange, Madeleine R, Fenner, Chia-Yi, Tseng, Barbara F, Akum, Bonnie L, Firestein
Publikováno v:
Molecular and Cellular Neuroscience. 123:103783
Cytosolic PSD-95 interactor (cypin) is a multifunctional, guanine deaminase that plays a major role in shaping the morphology of the dendritic arbor of hippocampal and cortical neurons. Cypin catalyzes the Zn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6367bb0729a67fa0b3bbb49cbd422dd
https://doi.org/10.1016/j.mcn.2022.103783
https://doi.org/10.1016/j.mcn.2022.103783
Autor:
Ana R. Rodriguez, Barbara F. Akum, David F. Meaney, Munjin Kwon, Bonnie L. Firestein, Erin D. Anderson, Tamara M. Stawicki, Kate O'Neill, Przemyslaw Peter McEwan, Nicholas F. Vigilante
Publikováno v:
Network Neuroscience
Network Neuroscience, Vol 5, Iss 1, Pp 166-197 (2021)
Network Neuroscience, Vol 5, Iss 1, Pp 166-197 (2021)
Cytosolic PSD-95 interactor (cypin) regulates many aspects of neuronal development and function, ranging from dendritogenesis to synaptic protein localization. While it is known that removal of postsynaptic density protein-95 (PSD-95) from the postsy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45cab76d18549005c7437d6251dd7bc1
https://pubmed.ncbi.nlm.nih.gov/33688611
https://pubmed.ncbi.nlm.nih.gov/33688611
Autor:
Joshua S. Goldberg, Rebecka Jörnsten, Bonnie L. Firestein, Barbara F. Akum, Christopher Rongo, Erik I. Charych, James Q. Zheng
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 26(40)
Dendritic morphology determines many aspects of neuronal function, including action potential propagation and information processing. However, the question remains as to how distinct neuronal dendrite branching patterns are established. Here, we repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::227ff6a1bcbd3e42fbca4d7d7b9fdd6b
https://pubmed.ncbi.nlm.nih.gov/17021172
https://pubmed.ncbi.nlm.nih.gov/17021172
Autor:
Barbara F. Akum, Gary M. Riefler, Kenyatta G. Lucas, Rebecka Jörnsten, Janine M. Provost, Maxine Chen, Gaithri Balasingam, Bonnie L. Firestein, Tamara M. Stawicki
Publikováno v:
Molecular biology of the cell. 16(11)
Temporal and spatial assembly of signal transduction machinery determines dendrite branch patterning, a process crucial for proper synaptic transmission. Our laboratory previously cloned and characterized cypin, a protein that decreases PSD-95 family
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82250f8468d28d2ab01b648488d62f12
https://pubmed.ncbi.nlm.nih.gov/16120643
https://pubmed.ncbi.nlm.nih.gov/16120643
Autor:
Monica M Scerri-Hansen, Barbara F. Akum, Bonnie L. Firestein, Maxine Chen, Samuel I. Gunderson, Gary M. Riefler
Publikováno v:
Nature neuroscience. 7(2)
Dendrite branching has an important role in normal brain function. Here we report that overexpression of cypin, a protein that has guanine deaminase activity and is expressed in developing processes in rat hippocampal neurons, results in increased de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c5a6827b69b823ffd3e4d16b8ac39d6
https://pubmed.ncbi.nlm.nih.gov/14730308
https://pubmed.ncbi.nlm.nih.gov/14730308