Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Barbara Emde"'
Autor:
Lena Kasper, Frederic Pipp, Bettina Hanschke, Michael Schmitt, Stephanie Czasch, Enrico Vigna, Anindya Siddharta, Stefan Weigt, Barbara Emde, Jürgen Hellmann, Sven Jäckel
Publikováno v:
Journal of pharmacological and toxicological methods. 110
Introduction Gastrointestinal (GI) toxicity is still an issue within drug development, especially for novel oncology drugs. The identification of GI mucosal damage at an early stage with high sensitivity and specificity across preclinical species and
Autor:
Anja Knippel, Jürgen Hellmann, Stefan Weigt, Stephanie Czasch, Anindya Siddharta, Michael Schmitt, Bettina Hanschke, Barbara Emde, Lena Kasper, Valentina Lai, Sven Jäckel
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 105:106863
Publikováno v:
Cell Biochemistry and Biophysics. 53:135-143
The endothelial cell (EC) membrane is an important interface, which plays a crucial role in signal transduction. Our aim was to selectively purify luminal EC membrane proteins from the coronary vasculature of the isolated perfused mouse heart and ana
Autor:
Otto W. Witte, Karl Zilles, Barbara Emde, Bernd Mayer, Hans-J. Bidmon, Kanefusa Kato, Marcus Schmitt, Kohtaro Asayama, Tilo Kowalski
Publikováno v:
Journal of Chemical Neuroanatomy. 22:167-184
Neuronal nitric oxide-I is constitutively expressed in approximately 2% of cortical interneurons and is co-localized with gamma-amino butric acid, somatostatin or neuropeptide Y. These interneurons additionally express high amounts of glutamate recep
Publikováno v:
Experimental Neurology. 168:1-22
Cerebral ischemic injury results in the liberation of heme from degenerating heme-containing proteins. The neurotoxic heme is usually detoxified by the constitutive heme oxygenase-2 (HO-2) and its inducible isoform HO-1(heat shock protein 32) resulti
Autor:
Friedrich von Landenberg, Stephanie Czasch, Katharina Frick, Philip G. Hewitt, Barbara Emde, Tobias Christian Fuchs
Publikováno v:
Toxicologic pathology. 40(7)
Novel urinary protein biomarkers for the detection of acute renal damage, recently accepted by the U.S. Food and Drug Administration, European Medicines Agency, and Pharmaceuticals and Medical Devices Agency (Japan), now have to be validated in pract
Publikováno v:
Circulation. 116
We recently reported that mice with targeted deletion of ecto-5′-nucleotidase (CD73) are characterized by enhanced platelet activation and increased adherence of monocytes to the endothelium. Wire-induced injury of the carotid artery resulted in en
Publikováno v:
Cell Biochemistry & Biophysics; Apr2009, Vol. 53 Issue 3, p135-143, 9p
Publikováno v:
FEMS Microbiology Letters. 42:69-74
The regular surface layers (S-layers) of two Deinococcus radiodurans strains R1 and Sark, undergo limited proteolysis during preparation. This is due to cellular proteases that create strain-specific polypeptide patterns in SDS-PAGE. Proteolytic acti