Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Barbara E. Wright"'
Publikováno v:
Mutation Research/Reviews in Mutation Research. 752:129-137
This review summarizes the evidence indicating that mutagenic mechanisms in vivo are essentially the same in all living cells. Unique metabolic reactions to a particular environmental stress apparently target specific genes for increased rates of tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52090655cd95c828a4ea50412be72b0b
https://doi.org/10.1016/j.mrrev.2012.12.003
https://doi.org/10.1016/j.mrrev.2012.12.003
Publikováno v:
Molecular Immunology. 45:3600-3608
The role of secondary structures and base mutability at different levels of transcription and supercoiling is analyzed in variable region antibody genes VH5, VH94 and VH186.2. The data are consistent with a model of somatic hypermutation in which inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4743add5947a6704ca45e24dea9c1e9
https://doi.org/10.1016/j.molimm.2008.05.012
https://doi.org/10.1016/j.molimm.2008.05.012
Autor:
Angelika Longacre, Dennis K. Reschke, Barbara E. Wright, Karen H. Schmidt, Jacqueline M. Reimers
Publikováno v:
Microbiology. 150:1457-1466
Escherichia coliauxotrophs ofleuBandargHwere examined to determine if higher rates of transcription in derepressed genes were correlated with increased reversion rates. Rates ofleuBandargHmRNA synthesis were determined using half-lives and concentrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc1fc67211695f2bc4b6890440f76d6c
https://doi.org/10.1099/mic.0.26954-0
https://doi.org/10.1099/mic.0.26954-0
Autor:
Barbara E. Wright
Publikováno v:
Molecular Microbiology. 52:643-650
Summary Comparative biochemistry demonstrates that the metabolites, complex biochemical networks, enzymes and regulatory mechanisms essential to all living cells are conserved in amazing detail throughout evolution. Thus, in order to evolve, an organ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::129f92475b1685cd2f846da8f424fcef
https://doi.org/10.1111/j.1365-2958.2004.04012.x
https://doi.org/10.1111/j.1365-2958.2004.04012.x
Autor:
William Knight, Karen H. Schmidt, Barbara E. Wright, Jacqueline M. Reimers, Dennis K. Reschke
Publikováno v:
Molecular Microbiology. 48:429-441
Summary This work provides evidence that, during transcription, the mutability (propensity to mutate) of a base in a DNA secondary structure depends both on the stability of the structure and on the extent to which the base is unpaired. Zuker ' s DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eda761ff64e29eb60cd8c57849a43537
https://doi.org/10.1046/j.1365-2958.2003.t01-1-03436.x
https://doi.org/10.1046/j.1365-2958.2003.t01-1-03436.x
Publikováno v:
Fungal Genetics and Biology. 21:30-39
A flux analysis of glucose metabolism in the filamentous fungus Rhizopus oryzae was achieved using a specific radioactivity curve-matching program, TFLUX. Glycolytic and tricarboxylic acid cycle intermediates labeled through the addition of extracell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8483eb8ed286438843c0b661e7d6c045
https://doi.org/10.1006/fgbi.1996.0952
https://doi.org/10.1006/fgbi.1996.0952
Autor:
Kathy R. Albe, Barbara E. Wright
Publikováno v:
Journal of Theoretical Biology. 169:231-241
A model of the transitional changes which occur in fluxes and metabolite concentrations during the course of differentiation of Dictyostelium discoideum is constructed, based on extensive experimental data collected from D. discoideum. Input to the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7455e37df6d90090da2fd8214505ecda
https://doi.org/10.1006/jtbi.1994.1144
https://doi.org/10.1006/jtbi.1994.1144
The VH5 human antibody gene was analyzed using a computer program (mfg) which simulates transcription, to better understand transcription-driven mutagenesis events that occur during “phase 1” of somatic hypermutation. Results show that the great
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ed016aa7b900244f8b6cb350416b097
https://europepmc.org/articles/PMC3235918/
https://europepmc.org/articles/PMC3235918/
Autor:
Aaron T. Hunt, Dennis K. Reschke, Karen H. Schmidt, Michael F. Minnick, J. Stephen Lodmell, Barbara E. Wright
Publikováno v:
Carcinogenesis. 32(10)
Transcription drives supercoiling which forms and stabilizes single-stranded (ss) DNA secondary structures with loops exposing G and C bases that are intrinsically mutable and vulnerable to non-enzymatic hydrolytic reactions. Since many studies in pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b3b667a58c38d1739cce4684d6f9271
https://pubmed.ncbi.nlm.nih.gov/21803733
https://pubmed.ncbi.nlm.nih.gov/21803733
Publikováno v:
Experimental Mycology. 17:1-6
Reimers, J. M., Huang, Q., Albe, K. R., and Wright, B. E. 1993. Purification and kinetic characterization of glucose-6-phosphate dehydrogenase from Dictyostelium discoideum. Experimental Mycology 17, 1-6. Glucose-6-phosphate dehydrogenase from Dictyo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa9bc7d0a4060b56c4d571b795271292
https://doi.org/10.1006/emyc.1993.1001
https://doi.org/10.1006/emyc.1993.1001