Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Barbara Dymek"'
Autor:
Piotr Sklepkiewicz, Barbara Dymek, Michal Mlacki, Agnieszka Zagozdzon, Magdalena Salamon, Anna Maria Siwińska, Marcin Piotr Mazurkiewicz, Natalia de Souza Xavier Costa, Marzena Mazur, Thais Mauad, Adam Gołębiowski, Karolina Dzwonek, Jakub Gołąb, Zbigniew Zasłona
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4719 (2023)
Chitotriosidase (CHIT1) is an enzyme produced by macrophages that regulates their differentiation and polarization. Lung macrophages have been implicated in asthma development; therefore, we asked whether pharmacological inhibition of macrophage-spec
Externí odkaz:
https://doaj.org/article/dd0739a2e29247d1af820227a88bf397
Autor:
Natalia Przysucha, Katarzyna Górska, Marta Maskey-Warzęchowska, Małgorzata Proboszcz, Patrycja Nejman-Gryz, Magdalena Paplińska-Goryca, Barbara Dymek, Agnieszka Zagozdzon, Rafał Krenke
Publikováno v:
Cells, Vol 11, Iss 23, p 3765 (2022)
Chitinases and chitinase-like proteins are thought to play a role in innate inflammatory responses. Our study aimed to assess whether chitinase concentration and activity in induced sputum (IS) of patients exposed to tobacco smoke are related to the
Externí odkaz:
https://doaj.org/article/a23d19c8adef410087eab04e1f1bf6ef
Autor:
Mariola Stypik, Marcin Zagozda, Stanisław Michałek, Barbara Dymek, Daria Zdżalik-Bielecka, Maciej Dziachan, Nina Orłowska, Paweł Gunerka, Paweł Turowski, Joanna Hucz-Kalitowska, Aleksandra Stańczak, Paulina Stańczak, Krzysztof Mulewski, Damian Smuga, Filip Stefaniak, Lidia Gurba-Bryśkiewicz, Arkadiusz Leniak, Zbigniew Ochal, Mateusz Mach, Karolina Dzwonek, Monika Lamparska-Przybysz, Krzysztof Dubiel, Maciej Wieczorek
Publikováno v:
Pharmaceuticals, Vol 15, Iss 8, p 949 (2022)
Phosphoinositide 3-kinase δ (PI3Kδ), a member of the class I PI3K family, is an essential signaling biomolecule that regulates the differentiation, proliferation, migration, and survival of immune cells. The overactivity of this protein causes cell
Externí odkaz:
https://doaj.org/article/4dd8c9f6c70e4b8898c041fd13130a7c
Publikováno v:
Dose-Response, Vol 7 (2009)
Accumulation of molecular damage and increased molecular heterogeneity are hallmarks of cellular aging. Mild stress-induced hormesis can be an effective way for reducing the accumulation of molecular damage, and thus slowing down aging from within. W
Externí odkaz:
https://doaj.org/article/2d195b3c1b714ff6a0810a296b2df52a
Autor:
Barbara Dymek, Piotr Sklepkiewicz, Michal Mlacki, Nazan Cemre Güner, Patrycja Nejman-Gryz, Katarzyna Drzewicka, Natalia Przysucha, Aleksandra Rymaszewska, Magdalena Paplinska-Goryca, Agnieszka Zagozdzon, Małgorzata Proboszcz, Łukasz Krzemiński, Jan H von der Thüsen, Katarzyna Górska, Karolina Dzwonek, Zbigniew Zasłona, Pawel Dobrzanski, Rafał Krenke
Publikováno v:
Journal of Inflammation Research, 15, 5621-5634. Dove Medical Press Ltd.
Barbara Dymek,1,2 Piotr Sklepkiewicz,1 Michal Mlacki,1 Nazan Cemre Güner,1 Patrycja Nejman-Gryz,3 Katarzyna Drzewicka,1 Natalia Przysucha,3 Aleksandra Rymaszewska,1 Magdalena Paplinska-Goryca,3 Agnieszka Zagozdzon,1 Małgorzata Proboszcz,3 &
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f22fb023a73bb4a50caade62b0347bf
https://doi.org/10.2147/jir.s378357
https://doi.org/10.2147/jir.s378357
Autor:
Robert Koralewski, Michał Kowalski, Krzysztof Matyszewski, Sylwia Olejniczak, Piotr L. Sklepkiewicz, Michal Piotrowicz, Czestkowski Wojciech J, Michal Mlacki, Adam Golebiowski, Karolina Dzwonek, Barbara Dymek, Magdalena Salamon, Bartlomiej Borek, Piotr Niedziejko, Agnieszka Bartoszewicz, Marcin Nowotny, Agnieszka Zagozdzon, Mariusz Gruza, Agnieszka Napiorkowska-Gromadzka, Aneta Bartlomiejczak, Pawel Dobrzanski, Marzena Mazur, Gleb Andryianau, Magdalena Kania, Jakub Golab, Pluta Elzbieta, Karol Jedrzejczak, Witold Mozga, Marcin Mazurkiewicz, Tomasz Rejczak, Jacek Olczak, Sylwia Piasecka, Aleksandra Rymaszewska
Publikováno v:
Journal of Medicinal Chemistry. 63:15527-15540
Chitotriosidase (CHIT1) and acidic mammalian chitinase (AMCase) are the enzymatically active chitinases that have been implicated in the pathology of chronic lung diseases such as asthma and inters...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2dd9844a8fb40d1518481d781cdfd6d
https://doi.org/10.1021/acs.jmedchem.0c01179
https://doi.org/10.1021/acs.jmedchem.0c01179
Autor:
Robert, Koralewski, Barbara, Dymek, Marzena, Mazur, Piotr, Sklepkiewicz, Sylwia, Olejniczak, Wojciech, Czestkowski, Krzysztof, Matyszewski, Gleb, Andryianau, Piotr, Niedziejko, Michal, Kowalski, Mariusz, Gruza, Bartłomiej, Borek, Karol, Jedrzejczak, Agnieszka, Bartoszewicz, Elżbieta, Pluta, Aleksandra, Rymaszewska, Magdalena, Kania, Tomasz, Rejczak, Sylwia, Piasecka, Michal, Mlacki, Marcin, Mazurkiewicz, Michał, Piotrowicz, Magdalena, Salamon, Agnieszka, Zagozdzon, Agnieszka, Napiorkowska-Gromadzka, Aneta, Bartlomiejczak, Witold, Mozga, Paweł, Dobrzański, Karolina, Dzwonek, Jakub, Golab, Marcin, Nowotny, Jacek, Olczak, Adam, Golebiowski
Publikováno v:
Journal of medicinal chemistry. 63(24)
Chitotriosidase (CHIT1) and acidic mammalian chitinase (AMCase) are the enzymatically active chitinases that have been implicated in the pathology of chronic lung diseases such as asthma and interstitial lung diseases (ILDs), including idiopathic pul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b9418f8d294ee157abcdfd2a01099fe4
https://pubmed.ncbi.nlm.nih.gov/33078933
https://pubmed.ncbi.nlm.nih.gov/33078933
Autor:
Robert Koralewski, Gleb Andryianau, Krzysztof Matyszewski, Bartlomiej Borek, Pluta Elzbieta, Adam Golebiowski, Marcin Mazurkiewicz, Jakub Golab, Barbara Dymek, Piotr Niedziejko, Czestkowski Wojciech J, Michal Piotrowicz, Michał Kowalski, Sylwia Olejniczak, Marzena Mazur, Jacek Olczak, Agnieszka Zagozdzon, Filip Stefaniak, Karolina Dzwonek, Agnieszka Bartoszewicz, Mariusz Gruza, Magdalena Salamon
Publikováno v:
Bioorganic & Medicinal Chemistry Letters
This article describes our work towards the identification of a potent and selective inhibitor of mouse chitotriosidase (mCHIT1). A series of small molecule inhibitors of mCHIT1 and mAMCase have been developed from early lead compound 1 . Examination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::340f6f7ae7b7c75d35d3b35d53144a21
https://doi.org/10.1016/j.bmcl.2017.12.047
https://doi.org/10.1016/j.bmcl.2017.12.047
Autor:
Agnieszka Bartoszewicz, Aleksandra Rymaszewska, Agnieszka Zagozdzon, Jakub Golab, Pawel Dobrzanski, Marcin Mazurkiewicz, Filip Stefaniak, Czestkowski Wojciech J, Adam Golebiowski, Bartlomiej Borek, Karolina Dzwonek, Robert Koralewski, Piotr L. Sklepkiewicz, Krzysztof Matyszewski, Barbara Dymek, Sylwia Olejniczak, Marzena Mazur, Michał Piotrowicz, Magdalena Salamon, Jacek Olczak, Pluta Elzbieta, Karol Jedrzejczak, Witold Mozga
Publikováno v:
Journal of medicinal chemistry. 62(15)
Acidic mammalian chitinase (AMCase) and chitotriosidase-1 (CHIT1) are two enzymatically active proteins produced by mammals capable of cleaving the glycosidic bond in chitin. Based on the clinical findings and animal model studies, involvement of chi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7391f2edfc78a24c715b46724e5643ef
https://pubmed.ncbi.nlm.nih.gov/31291098
https://pubmed.ncbi.nlm.nih.gov/31291098
Autor:
Michal Mlacki, Barbara Dymek, Agnieszka Zagozdzon, Marzena Mazur, Robert Koralewski, Adam Golebiewski, Karolina Dzwonek, Pawel Dobrzanski
Publikováno v:
Journal of Hepatology. 73:S451
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b532b463cedf4cd46ed143856234377
https://doi.org/10.1016/s0168-8278(20)31383-0
https://doi.org/10.1016/s0168-8278(20)31383-0