Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Barbara Doggett"'
Autor:
Melissa A. Parisi, Audrey Baldessari, Malissa H K Iida, Barbara Doggett, Raj P. Kapur, Christine M Clarke, Senji Shirasawa
Publikováno v:
Gastroenterology. 125:1428-1440
Background & Aims: The transcription factor Hox11L1 is expressed by enteric neurons. Two groups mutated murine Hox11L1 , and reported lethal intestinal pseudo-obstruction and colonic hyperganglionosis in many, but not all, homozygous null mutants. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5171b4a936ed408e8c8c6ddd3425ace4
https://doi.org/10.1016/j.gastro.2003.08.021
https://doi.org/10.1016/j.gastro.2003.08.021
Autor:
David A. Sweetser, Julie Rice, Masashi Yanagisawa, Barbara Doggett, Raj P. Kapur, Hiromi Yanagisawa
Publikováno v:
Developmental Dynamics. 217:120-132
Complete colonization of the gut by enteric neural precursors depends on activation of ednrB and Ret receptors by their respective ligands, edn3 and gdnf. Mutations that eliminate expression of either ligand or either receptor produce intestinal agan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8a2d6be717bac01712b73345a284425
https://doi.org/10.1002/(sici)1097-0177(200001)217:1<120::aid-dvdy11>3.0.co
https://doi.org/10.1002/(sici)1097-0177(200001)217:1<120::aid-dvdy11>3.0.co
Publikováno v:
Europe PubMed Central
Mice homozygous for the piebald lethal (sl) mutation, which have a complete deletion of endothelin receptor-B, fail to form ganglion cells in the distal large intestine and are nearly devoid of cutaneous melanocytes. These phenotypic features stem fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88091e9bb1ac6901d36d78201de31a34
https://doi.org/10.1242/dev.121.11.3787
https://doi.org/10.1242/dev.121.11.3787
Publikováno v:
Teratology. 49:135-142
A monoclonal antibody to the 72 kD heat shock protein (HSP 72), Western blot analysis and 2-D gel electrophoresis/autoradiography were used to determine whether selected chemical teratogens induced the synthesis and accumulation of HSP 72 in postimpl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7951274c436b2db39a33109cd86adfed
https://doi.org/10.1002/tera.1420490209
https://doi.org/10.1002/tera.1420490209
Autor:
Philip E. Mirkes, Barbara Doggett
Publikováno v:
Teratology. 46:301-309
A monoclonal antibody to the 72 kDa heat shock protein and Western blot analysis were used to determine the induction, accumulation and turnover of hsp 72 after day 10 rat embryos were exposed to elevated temperatures (40 degrees-43 degrees C) for va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26307482de9b5d63b6b69220f91b4263
https://doi.org/10.1002/tera.1420460315
https://doi.org/10.1002/tera.1420460315
Autor:
Zhenqiang Yao, Barbara Doggett, Raj P. Kapur, Malissa H K Iida, Lianping Xing, Christine M Clarke, Brendan F. Boyce
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 19(10)
We report the first case of lethal autosomal recessive osteopetrosis in mice caused by a spontaneous 8-bp deletion in exon 2 of the Rank gene. The phenotype, including a block in RANKL-dependent osteoclast differentiation and lymph node agenesis, cop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89b6863eedb98b79fe82891131a54cd0
https://pubmed.ncbi.nlm.nih.gov/15355564
https://pubmed.ncbi.nlm.nih.gov/15355564
Autor:
Melissa A, Parisi, Audrey E, Baldessari, Malissa H K, Iida, Christine M, Clarke, Barbara, Doggett, Senji, Shirasawa, Raj P, Kapur
Publikováno v:
Gastroenterology. 125(5)
The transcription factor Hox11L1 is expressed by enteric neurons. Two groups mutated murine Hox11L1, and reported lethal intestinal pseudo-obstruction and colonic hyperganglionosis in many, but not all, homozygous null mutants. We investigated the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9980ea6833393efffcf03db9cef80fdd
https://pubmed.ncbi.nlm.nih.gov/14598259
https://pubmed.ncbi.nlm.nih.gov/14598259
The tyrosine kinase receptor Ret is expressed in the ureteric bud and is required for normal renal development. Constitutive loss of Ret, its co-receptor gfralpha-1, or the ligand glial cell line-derived neurotrophic factor results in renal agenesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08797ea2d49b510f4f5f44b25321815f
https://europepmc.org/articles/PMC1866938/
https://europepmc.org/articles/PMC1866938/
Publikováno v:
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society. 1(6)
Methotrexate, a potent inhibitor of the ubiquitously expressed enzyme dihydrofolate reductase, induces limb and facial anomalies that resemble vascular disruptions in their evolution and final outcome. Previous studies suggest that inhibition of dihy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a74ac8e316762a444b0e3a3938d8f634
https://pubmed.ncbi.nlm.nih.gov/9724337
https://pubmed.ncbi.nlm.nih.gov/9724337
Autor:
Robert B. Livingston, Raj P. Kapur, David A. Sweetser, Richard D. Palmiter, Joseph R. Siebert, Barbara Doggett
Publikováno v:
Developmental biology. 174(2)
Dominant megacolon (Dom) is a mutation in an uncharacterized murine gene which is associated with intestinal aganglionosis and the focal absence of melanocytes in heterozygous animals. The phenotype of Dom/+ heterozygotes is similar to the lethal spo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b08e4ba2ea5cd1e7cad487855af203b2
https://pubmed.ncbi.nlm.nih.gov/8631507
https://pubmed.ncbi.nlm.nih.gov/8631507