Tolerability of vortioxetine compared to selective serotonin reuptake inhibitors in older adults with major depressive disorder (VESPA): a randomised, assessor-blinded and statistician-blinded, multicentre, superiority trialResearch in context

Autor: Giovanni Ostuzzi, Chiara Gastaldon, Mauro Tettamanti, Massimo Cartabia, Igor Monti, Andrea Aguglia, Eugenio Aguglia, Francesco Bartoli, Camilla Callegari, Andrea Canozzi, Elvira Anna Carbone, Giuseppe Carrà, Rosangela Caruso, Simone Cavallotti, Stefania Chiappini, Fabrizio Colasante, Beatrice Compri, Armando D'Agostino, Pasquale De Fazio, Renato de Filippis, Matteo Gari, Marta Ielmini, Gianmarco Ingrosso, Silvia Mammarella, Giovanni Martinotti, Alessandro Rodolico, Rita Roncone, Enrico Sterzi, Lorenzo Tarsitani, Elisa Tiberto, Liliana Todini, Francesco Amaddeo, Barbara D'Avanzo, Angelo Barbato, Corrado Barbui, Maria Chiara Alessi, Gabriele Avincola, Bianca Bachi, Gianna Bernasconi, Andrea Birgillito, Emanuele Bisso, Stefano Bonora, Angela Calabrese, Tommaso Callovini, Aurelia Canestro, Salvo Canonico, Chiara Alessandro Capogrosso, Elvira Carbone, Doriana Carosielli, Ivano Caselli, Daniele Cavaleri, Clara Cavallotto, Marco Cesca, Cecilia Chiarenza, Riccardo Matteo Cioni, Sara Coloccini, Marco Cruciata, Claudia Cumerlato, Renato De Filippis, Manuela De Palma, Sasha Del Vecchio, Bianca Della Rocca, Chiara Di Natale, Ettore D'Onofrio, Irene Espa, Giulia Fior, Marta Gancitano, Barbara Giordano, Laura Giusti, Luigi Grassi, Pierluca Guzzi, Celeste Isella, Annamaria Lax, Leonardo Marano, Federico Marconi, Marco Marella, Alessia Metelli, Giulia Michencig, Andrea Miuli, Alessandro Moncada, Pietro Morello, Federico Moretti, Marco Morreale, Alessio Mosca, Christian Nasti, Michela Nosé, Filippo Ogheri, Margherita Oresti, Alessandra Ornaghi, Dario Palpella, Corinna Pancheri, Davide Papola, Silvia Passeri, Mauro Pettorusso, Susanna Piacenti, Irene Pinucci, Valentina Pugliese, Marianna Purgato, Marianna Rania, Federica Robbi, Samantha Romito, Barbara Ronchi, Valentina Roselli, Cristina Segura-Garcia, Maria Salvina Signorelli, Gabriele Simonelli, Antonella Sociali, Serena Sturiale, Antonio Tambelli, Beatrice Todesco, Alice Trabucco, Giulia Turrini, Veronica Villa, Federico Wiedenmann, Luca Zambuto, Elisa Zanini, Chiara Zannini, Luigi Zerbinati

Publikováno v: EClinicalMedicine, Vol 69, Iss , Pp 102491- (2024)

Summary: Background: Major depressive disorder (MDD) is prevalent and disabling among older adults. Standing on its tolerability profile, vortioxetine might be a promising alternative to selective serotonin reuptake inhibitors (SSRIs) in such a vulne

Externí odkaz: https://doaj.org/article/b6d9532a29514d6885cce2880822f39b

Using big data and Population Health Management to assess care and costs for patients with severe mental disorders and move toward a value-based payment system

Autor: Valeria D. Tozzi, Helen Banks, Lucia Ferrara, Angelo Barbato, Giovanni Corrao, Barbara D’avanzo, Teresa Di Fiandra, Andrea Gaddini, Matteo Monzio Compagnoni, Michele Sanza, Alessio Saponaro, Salvatore Scondotto, Antonio Lora

Publikováno v: BMC Health Services Research, Vol 23, Iss 1, Pp 1-14 (2023)

Abstract Background Mental health (MH) care often exhibits uneven quality and poor coordination of physical and MH needs, especially for patients with severe mental disorders. This study tests a Population Health Management (PHM) approach to identify

Externí odkaz: https://doaj.org/article/7e9d7960635a4e15be0ef414fe2f12c0

From contact coverage to effective coverage of community care for patients with severe mental disorders: A real-world investigation from Italy

Autor: Giovanni Corrao, Matteo Monzio Compagnoni, Angelo Barbato, Barbara D’Avanzo, Teresa Di Fiandra, Lucia Ferrara, Andrea Gaddini, Alessio Saponaro, Salvatore Scondotto, Valeria D. Tozzi, Flavia Carle, Simona Carbone, Daniel H. Chisholm, Antonio Lora

Publikováno v: Frontiers in Psychiatry, Vol 13 (2022)

ObjectivesTo measure the gap between contact and effective coverage of mental healthcare (MHC).Materials and methods45,761 newly referred cases of depression, schizophrenia, bipolar disorder, and personality disorder from four Italian regions were in

Externí odkaz: https://doaj.org/article/ba557aeaf8564c61b58d4f466f0d7a0b

Willingness to share contacts in case of COVID-19 positivity–predictors of collaboration resistance in a nation-wide Italian survey

Autor: Boris Bikbov, Mauro Tettamanti, Alexander Bikbov, Barbara D’Avanzo, Alessia Antonella Galbussera, Alessandro Nobili, Gemma Calamandrei, Valentina Candini, Fabrizio Starace, Cristina Zarbo, Giovanni de Girolamo

Publikováno v: PLoS ONE, Vol 17, Iss 9 (2022)

Background The unwillingness to share contacts is one of the least explored aspects of the COVID-19 pandemic. Here we report the factors associated with resistance to collaborate on contact tracing, based on the results of a nation-wide survey conduc

Externí odkaz: https://doaj.org/article/42739814a58140adbf1628d13a83723f

Interventions to prevent, delay or reverse frailty in older people: a journey towards clinical guidelines

Autor: Maura Marcucci, Sarah Damanti, Federico Germini, Joao Apostolo, Elzbieta Bobrowicz-Campos, Holly Gwyther, Carol Holland, Donata Kurpas, Maria Bujnowska-Fedak, Katarzyna Szwamel, Silvina Santana, Alessandro Nobili, Barbara D’Avanzo, Antonio Cano

Publikováno v: BMC Medicine, Vol 17, Iss 1, Pp 1-11 (2019)

Abstract Background Age-related frailty is a multidimensional dynamic condition associated with adverse patient outcomes and high costs for health systems. Several interventions have been proposed to tackle frailty. This correspondence article descri

Externí odkaz: https://doaj.org/article/13a9af2898ff46528b8af335506f798c