Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Barbara Cristofanelli"'
Autor:
Eliana Munarriz, Luisa Castagnoli, Moshe Oren, Arnold J. Levine, Yosef Shaul, Ada Sacchi, Gianni Cesareni, Barbara Cristofanelli, Sabrina Strano, Mario Rossi, Giovanni Blandino
Publikováno v:
Journal of Biological Chemistry. 275:29503-29512
p53 is the most frequently inactivated tumor suppressor gene in human cancer, whereas its homologue, p73, is rarely mutated. Similarly to p53, p73 can promote growth arrest or apoptosis when overexpressed in certain p53-null tumor cells. It has previ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2998e525fcea0f548f5a7caacf05876d
https://doi.org/10.1074/jbc.m003360200
https://doi.org/10.1074/jbc.m003360200
Autor:
Giovanni Blandino, Ada Sacchi, Mg Rizzo, S Giuliacci, Raffaella Scardigli, Marco Crescenzi, Silvia Soddu, Sergio Ferrari, Barbara Cristofanelli, A Zepparoni
Publikováno v:
British Journal of Cancer
ResearcherID
ResearcherID
Recent studies support the potential application of the wt-p53 gene in cancer therapy. Expression of exogenous wt-p53 suppresses a variety of leukaemia phenotypes by acting on cell survival, proliferation and/or differentiation. As for tumour gene th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbd8cde9065846c69a67837ce43eee28
https://doi.org/10.1038/bjc.1998.236
https://doi.org/10.1038/bjc.1998.236
Autor:
Maria Giulia Rizzo, Barbara Cristofanelli, Anna Rita Morena, Alessandra Marchetti, Silvia Soddu, Michael Dews, Renato Baserga, Barbara Valentinis, Gianluca Bossi, Ada Sacchi
Publikováno v:
Scopus-Elsevier
32D cells expressing v-Ha-Ras fail to show a transformed phenotype. Since Ras requires an active IGF-1R for transformation of fibroblasts, we asked whether expression of IRS-1 or Shc (two of the major substrates of the IGF-1R) could co-operate with o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eab2a6cf061f8ee5351aee73e492465d
https://pubmed.ncbi.nlm.nih.gov/10918581
https://pubmed.ncbi.nlm.nih.gov/10918581
Autor:
Barbara Valentinis, Marco Prisco, Silvia Soddu, Barbara Cristofanelli, Gaetano Romano, Andrea Morrione, Francesca Peruzzi, Renato Baserga, Ada Sacchi
Publikováno v:
The Journal of biological chemistry. 274(18)
The type 1 insulin-like growth factor receptor (IGF-IR) plays an important role in the growth of cells both in vivo and in vitro. The IGF-IR is also capable of inducing differentiation in a number of cell types, raising the question of how the same r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::582efac94147c1597b854c8aea07cc67
https://pubmed.ncbi.nlm.nih.gov/10212216
https://pubmed.ncbi.nlm.nih.gov/10212216