Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Barbara Celona"'
Autor:
Christa Caggiano, Barbara Celona, Fleur Garton, Joel Mefford, Brian L. Black, Robert Henderson, Catherine Lomen-Hoerth, Andrew Dahl, Noah Zaitlen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Tissue damage and turnover lead to the release of DNA in the blood and can be used to monitor changes in tissue state. Here, the authors developed a tool to accurately estimate the proportion of cell types contributing to cell-free DNA in the blood,
Externí odkaz:
https://doaj.org/article/62dbc7a6c1794343b7f121153359fe9f
Publikováno v:
Cell Reports, Vol 8, Iss 6, Pp 1639-1648 (2014)
Skeletal muscle comprises a heterogeneous population of fibers with important physiological differences. Fast fibers are glycolytic and fatigue rapidly. Slow fibers utilize oxidative metabolism and are fatigue resistant. Muscle diseases such as sarco
Externí odkaz:
https://doaj.org/article/6113227820e44375b858c0d38defce34
Autor:
Barbara Celona, John von Dollen, Sarat C Vatsavayai, Risa Kashima, Jeffrey R Johnson, Amy A Tang, Akiko Hata, Bruce L Miller, Eric J Huang, Nevan J Krogan, William W Seeley, Brian L Black
Publikováno v:
eLife, Vol 6 (2017)
Expanded GGGGCC repeats in the first intron of the C9orf72 gene represent the most common cause of familial amyotrophic lateral sclerosis (ALS), but the mechanisms underlying repeat-induced disease remain incompletely resolved. One proposed gain-of-f
Externí odkaz:
https://doaj.org/article/7f808a4696024cde9c96b1dbd8a38c0c
Autor:
Rita Nano, Leda Racanicchi, Raffaella Melzi, Alessia Mercalli, Paola Maffi, Valeria Sordi, Zhidong Ling, Marina Scavini, Olle Korsgren, Barbara Celona, Antonio Secchi, Lorenzo Piemonti
Publikováno v:
Cell Transplantation, Vol 22 (2013)
High levels of donor-derived high-mobility group box 1 (HMGB1) protein have been associated with poor islet graft outcome in mouse models. The aim of our work was to determine whether HMGB1 released by human islets had independent proinflammatory eff
Externí odkaz:
https://doaj.org/article/014cbab31c15498483a06f9dd21da883
Autor:
Barbara Celona, Assaf Weiner, Francesca Di Felice, Francesco M Mancuso, Elisa Cesarini, Riccardo L Rossi, Lorna Gregory, Dilair Baban, Grazisa Rossetti, Paolo Grianti, Massimiliano Pagani, Tiziana Bonaldi, Jiannis Ragoussis, Nir Friedman, Giorgio Camilloni, Marco E Bianchi, Alessandra Agresti
Publikováno v:
PLoS Biology, Vol 9, Iss 6, p e1001086 (2011)
The basic unit of genome packaging is the nucleosome, and nucleosomes have long been proposed to restrict DNA accessibility both to damage and to transcription. Nucleosome number in cells was considered fixed, but recently aging yeast and mammalian c
Externí odkaz:
https://doaj.org/article/ddef3524839b4c52ab59154434198fc1
Autor:
Barbara Celona, Haifan Wu, Bobo Dang, Huong T. Kratochvil, William F. DeGrado, Brian L. Black
Expansion of intronic GGGGCC repeats in theC9orf72gene causes amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Transcription of the expanded repeats results in the formation of RNA-containing nuclear foci and altered RNA metabol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5306c4859c701afd627c3012165060cc
https://doi.org/10.1101/2023.03.05.531055
https://doi.org/10.1101/2023.03.05.531055
Autor:
Barbara Celona, Joel Mefford, Noah Zaitlen, Brian L. Black, Christa Caggiano, Robert D. Henderson, Catherine Lomen-Hoerth, Andrew Dahl, Fleur C. Garton
Publikováno v:
Nature communications, vol 12, iss 1
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Circulating cell-free DNA (cfDNA) in the bloodstream originates from dying cells and is a promising noninvasive biomarker for cell death. Here, we propose an algorithm, CelFiE, to accurately estimate the relative abundances of cell types and tissues
Autor:
Anna G Hauswirth, Barbara Celona, Richard D. Fetter, Graeme W. Davis, Len A. Pennacchio, Giulia Zunino, Evgeny Z. Kvon, Yiwen Zhu, Brian L. Black, Brian O. Orr
Publikováno v:
Neuron
Neuron, vol 107, iss 1
Neuron, vol 107, iss 1
Progressive synapse loss is an inevitable and insidious part of age-related neurodegenerative disease. Typically, synapse loss precedes symptoms of cognitive and motor decline. This suggests the existence of compensatory mechanisms that can temporari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82fb77780c986627c73d81d410ca92de
https://europepmc.org/articles/PMC7529479/
https://europepmc.org/articles/PMC7529479/
Autor:
Lorenzo Calviello, Chuwen Lin, Brian L. Black, Xuan Jiang, Prajakta Ghatpande, Amit Prabhakar, Wanpeng Wang, Giorgio Lagna, Srivats Venkataramanan, Stephanie M. Van der Voorn, Barbara Celona, Stephen N. Floor, Akiko Hata
Ribosome biogenesis in eukaryotes requires stoichiometric production and assembly of 80 ribosomal proteins (RPs) and 4 ribosomal RNAs, and its rate must be coordinated with cellular growth. The indispensable regulator of RP biosynthesis is the 5’-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bfe07765dad3d859029cac338af1d08
https://doi.org/10.1101/2020.04.24.060236
https://doi.org/10.1101/2020.04.24.060236
Autor:
Noah Zaitlen, Catherine Lomen-Hoerth, Christa Caggiano, Brian L. Black, Joel Mefford, Andrew Dahl, Fleur C. Garton, Barbara Celona
Circulating cell-free DNA (cfDNA) in the bloodstream originates from dying cells and is a promising non-invasive biomarker for cell death. Here, we develop a method to accurately estimate the relative abundances of cell types contributing to cfDNA. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b30b9c71d0a99f99e8689124fdffca54
https://doi.org/10.1101/2020.01.15.907022
https://doi.org/10.1101/2020.01.15.907022