Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Barbara Camisa"'
Autor:
Beatrice Claudia Cianciotti, Zulma Irene Magnani, Alessia Ugolini, Barbara Camisa, Ivan Merelli, Valentina Vavassori, Alessia Potenza, Antonio Imparato, Francesco Manfredi, Danilo Abbati, Laura Perani, Antonello Spinelli, Eric Shifrut, Fabio Ciceri, Luca Vago, Raffaella Di Micco, Luigi Naldini, Pietro Genovese, Eliana Ruggiero, Chiara Bonini
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundIn adoptive T cell therapy, the long term therapeutic benefits in patients treated with engineered tumor specific T cells are limited by the lack of long term persistence of the infused cellular products and by the immunosuppressive mechani
Externí odkaz:
https://doaj.org/article/0c75a1d1ee5c498d8c626e70eae69c03
Autor:
Alice Bergamini, Barbara Camisa, Chiara Bonini, Monica Casucci, Laura Falcone, Elena Tiziano, Rita El Khoury, Rossana Norata, Francesca Sanvito, Tamara Canu, Patrizia D’Adamo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/4e7adbfd3937411d923ad201549d10cb
Autor:
Alice Bergamini, Barbara Camisa, Fabio Ciceri, Chiara Bonini, Monica Casucci, Beatrice Greco, Federica Pedica, Chiara Balestrieri, Laura Falcone, Miriam Redegalli, Elena Tiziano, Camilla Sirini, Giovanni Tonon, Rita El Khoury, Oronzina Botrugno
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/6820359e0066459fad42c748e3f33dd2
Autor:
Alice Bergamini, Barbara Camisa, Attilio Bondanza, Fabio Ciceri, Chiara Bonini, Monica Casucci, Beatrice Greco, Camilla Bove, Silvia Arcangeli, Laura Falcone, Rita El Khoury, Anna De Lucia
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 1 (2023)
Background To date, T cells redirected with CD19-specific chimeric antigen receptors (CAR) have gained impressive success in B-cell malignancies. However, treatment failures are common and the occurrence of severe toxicities, such as cytokine release
Externí odkaz:
https://doaj.org/article/f7f0700140a54a238b7f036e7241a8c9
Autor:
Silvia Arcangeli, Camilla Bove, Claudia Mezzanotte, Barbara Camisa, Laura Falcone, Francesco Manfredi, Eugenia Bezzecchi, Rita El Khoury, Rossana Norata, Francesca Sanvito, Maurilio Ponzoni, Beatrice Greco, Marta Angiola Moresco, Matteo G. Carrabba, Fabio Ciceri, Chiara Bonini, Attilio Bondanza, Monica Casucci
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 12 (2022)
Chimeric antigen receptor (CAR) T cell expansion and persistence represent key factors to achieve complete responses and prevent relapses. These features are typical of early memory T cells, which can be highly enriched through optimized manufacturin
Externí odkaz:
https://doaj.org/article/81d1da4c079b452abf38886ebf969f0d
Autor:
Emanuela Brunetto, Lucia De Monte, Gianpaolo Balzano, Barbara Camisa, Vincenzo Laino, Michela Riba, Silvia Heltai, Marco Bianchi, Claudio Bordignon, Massimo Falconi, Attilio Bondanza, Claudio Doglioni, Maria Pia Protti
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract Background The thymic stromal lymphopoietin (TSLP), a key cytokine for development of Th2 immunity, is produced by cancer associated fibroblasts (CAFs) in pancreatic cancer where predominant tumor infiltrating Th2 over Th1 cells correlates w
Externí odkaz:
https://doaj.org/article/5c520e7584044e6583d6a653cc0b822d
Autor:
Silvia Arcangeli, Laura Falcone, Barbara Camisa, Federica De Girardi, Marta Biondi, Fabio Giglio, Fabio Ciceri, Chiara Bonini, Attilio Bondanza, Monica Casucci
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Chimeric antigen receptor (CAR) T cell expansion and persistence emerged as key efficacy determinants in cancer patients. These features are typical of early-memory T cells, which can be enriched with specific manufacturing procedures, providing sign
Externí odkaz:
https://doaj.org/article/566b2b6edfac40ce85ed4f163b8a2092
Autor:
Giulia Escobar, Luigi Barbarossa, Giulia Barbiera, Margherita Norelli, Marco Genua, Anna Ranghetti, Tiziana Plati, Barbara Camisa, Chiara Brombin, Davide Cittaro, Andrea Annoni, Attilio Bondanza, Renato Ostuni, Bernhard Gentner, Luigi Naldini
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
An immune suppressive tumor microenvironment (TME) is a limitation for immunotherapy. Here the authors show that, in a B cell acute lymphoblastic leukemia mouse model, gene-based delivery of IFNα reprograms the leukemia-induced immunosuppressive TME
Externí odkaz:
https://doaj.org/article/d5447487f0d9463493bef78ed95681ca
Autor:
Monica Casucci, Laura Falcone, Barbara Camisa, Margherita Norelli, Simona Porcellini, Anna Stornaiuolo, Fabio Ciceri, Catia Traversari, Claudio Bordignon, Chiara Bonini, Attilio Bondanza
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Chimeric antigen receptor (CAR)-T cell immunotherapy is at the forefront of innovative cancer therapeutics. However, lack of standardization of cellular products within the same clinical trial and lack of harmonization between different trials have h
Externí odkaz:
https://doaj.org/article/2fbad32be4d1496aa39b24a192390c94
Autor:
Eliana Ruggiero, Erica Carnevale, Aaron Prodeus, Zulma Irene Magnani, Barbara Camisa, Ivan Merelli, Claudia Politano, Lorena Stasi, Alessia Potenza, Beatrice Claudia Cianciotti, Francesco Manfredi, Mattia Di Bono, Luca Vago, Michela Tassara, Sara Mastaglio, Maurilio Ponzoni, Francesca Sanvito, Dai Liu, Ishina Balwani, Rossella Galli, Marco Genua, Renato Ostuni, Matteo Doglio, Daniel O’Connell, Ivy Dutta, Stephanie Ann Yazinski, Mark McKee, Mohamed Simo Arredouani, Birgit Schultes, Fabio Ciceri, Chiara Bonini
Publikováno v:
Science translational medicine 14 (2022). doi:10.1126/scitranslmed.abg8027
info:cnr-pdr/source/autori:Ruggiero, Eliana; Carnevale, Erica; Prodeus, Aaron; Magnani, Zulma Irene; Camisa, Barbara; Merelli, Ivan; Politano, Claudia; Stasi, Lorena; Potenza, Alessia; Cianciotti, Beatrice Claudia; Manfredi, Francesco; Di Bono, Mattia; Vago, Luca; Tassara, Michela; Mastaglio, Sara; Ponzoni, Maurilio; Sanvito, Francesca; Liu, Dai; Balwani, Ishina; Galli, Rossella; Genua, Marco; Ostuni, Renato; Doglio, Matteo; O'Connell, Daniel; Dutta, Ivy; Yazinski, Stephanie Ann; McKee, Mark; Arredouani, Mohamed Simo; Schultes, Birgit; Ciceri, Fabio; Bonini, Chiara/titolo:CRISPR-based gene disruption and integration of high-avidity, WT1-specific T cell receptors improve antitumor T cell function/doi:10.1126%2Fscitranslmed.abg8027/rivista:Science translational medicine/anno:2022/pagina_da:/pagina_a:/intervallo_pagine:/volume:14
info:cnr-pdr/source/autori:Ruggiero, Eliana; Carnevale, Erica; Prodeus, Aaron; Magnani, Zulma Irene; Camisa, Barbara; Merelli, Ivan; Politano, Claudia; Stasi, Lorena; Potenza, Alessia; Cianciotti, Beatrice Claudia; Manfredi, Francesco; Di Bono, Mattia; Vago, Luca; Tassara, Michela; Mastaglio, Sara; Ponzoni, Maurilio; Sanvito, Francesca; Liu, Dai; Balwani, Ishina; Galli, Rossella; Genua, Marco; Ostuni, Renato; Doglio, Matteo; O'Connell, Daniel; Dutta, Ivy; Yazinski, Stephanie Ann; McKee, Mark; Arredouani, Mohamed Simo; Schultes, Birgit; Ciceri, Fabio; Bonini, Chiara/titolo:CRISPR-based gene disruption and integration of high-avidity, WT1-specific T cell receptors improve antitumor T cell function/doi:10.1126%2Fscitranslmed.abg8027/rivista:Science translational medicine/anno:2022/pagina_da:/pagina_a:/intervallo_pagine:/volume:14
T cell receptor (TCR)–based therapy has the potential to induce durable clinical responses in patients with cancer by targeting intracellular tumor antigens with high sensitivity and by promoting T cell survival. However, the need for TCRs specific