Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Barbara Burgoyne"'
Publikováno v:
Biotechnology Progress. 36
The Food and Drug Administration (FDA) initiative of Process Analytical Technology (PAT) encourages the monitoring of biopharmaceutical manufacturing processes by innovative solutions. Raman spectroscopy and the chemometric modeling tool partial leas
Autor:
Carl Rafferty, Karin M. Balss, Dan Hill, Olav Lyngberg, Jim O'Mahony, Caitlin O’Mahony-Hartnett, Rosemary Rea, Barbara Burgoyne, Eugene Schaefer
Publikováno v:
Bioprocess and biosystems engineering. 43(8)
Multiple process analytical technology (PAT) tools are now being applied in tandem for cell culture. Research presented used two in-line probes, capacitance for a dynamic feeding strategy and Raman spectroscopy for real-time monitoring. Data collecte
Autor:
David C. Latshaw, Carl Rafferty, Barbara Burgoyne, Rosemary Rea, Jim O'Mahony, Karin M. Balss
Publikováno v:
Biotechnology and bioengineeringREFERENCES. 117(1)
Raman spectroscopy is a robust, well-established tool utilized for measuring important cell culture process variables for example, feed, metabolites, and biomass in real-time. This study further expands the functionality of in-line Raman spectroscopy