Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Barbara Budzyńska"'
Autor:
Piotr Stępnicki, Olga Wronikowska-Denysiuk, Agata Zięba, Katarzyna M. Targowska-Duda, Agata Bartyzel, Martyna Z. Wróbel, Tomasz M. Wróbel, Klaudia Szałaj, Andrzej Chodkowski, Karolina Mirecka, Barbara Budzyńska, Emilia Fornal, Jadwiga Turło, Marián Castro, Agnieszka A. Kaczor
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
AbstractSchizophrenia is a chronic mental disorder that is not satisfactorily treated with available antipsychotics. The presented study focuses on the search for new antipsychotics by optimising the compound D2AAK3, a multi-target ligand of G-protei
Externí odkaz:
https://doaj.org/article/7d0e4b8d609e40c3b4670a0604436c47
Autor:
Joanna Kowalczyk, Barbara Budzyńska, Łukasz Kurach, Daniele Pellegata, Nesrine S. El Sayed, Jürg Gertsch, Krystyna Skalicka-Woźniak
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Scoparone (6,7-dimethoxycoumarin) is a simple coumarin from botanical drugs of Artemisia species used in Traditional Chinese Medicine and Génépi liquor. However, its bioavailability to the brain and potential central effects remain unexplo
Externí odkaz:
https://doaj.org/article/94186d10ee4b46908e20e819a998a71c
Autor:
Łukasz Kurach, Agnieszka Chłopaś-Konowałek, Barbara Budzyńska, Marcin Zawadzki, Paweł Szpot, Anna Boguszewska-Czubara
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Synthetic opioids are gaining more and more popularity among recreational users as well as regular abusers. One of such novel psychoactive substance, is etazene, which is the most popular opioid drug in the darknet market nowadays. Due to li
Externí odkaz:
https://doaj.org/article/964111600cff402dbaea7835e58b0083
Autor:
Wojciech Świątkowski, Barbara Budzyńska, Monika Maciąg, Agnieszka Świątkowska, Przemko Tylżanowski, Mansur Rahnama-Hezavah, Piotr Stachurski, Renata Chałas
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 12094 (2023)
Tobacco smoking is one of the most serious health problems. Potentially lethal effects of nicotine for adults can occur with as little as 30 to 60 mg, although severe symptoms can arise with lower doses. Furthermore, the route of administration also
Externí odkaz:
https://doaj.org/article/970421040b8c4891aba175b2db2d0000
Autor:
Olga Wronikowska-Denysiuk, Agnieszka Michalak, Anna Pankowska, Łukasz Kurach, Paulina Kozioł, Artur Łazorczyk, Katarzyna Kochalska, Katarzyna Targowska-Duda, Anna Boguszewska-Czubara, Barbara Budzyńska
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 9958 (2023)
Mephedrone is a psychoactive drug that increases dopamine, serotonin and noradrenaline levels in the central nervous system via interaction with transporters or monoamines. The aim of the presented study was to assess the role of the GABA-ergic syste
Externí odkaz:
https://doaj.org/article/b79e7d9e5b454c17ba8f4e98494560c4
Autor:
Adrianna Skiba, Daniele Pellegata, Veronika Morozova, Ewelina Kozioł, Barbara Budzyńska, Simon Ming-Yuen Lee, Jürg Gertsch, Krystyna Skalicka-Woźniak
Publikováno v:
Cells, Vol 12, Iss 11, p 1540 (2023)
Zebrafish (Danio rerio) assays provide a versatile pharmacological platform to test compounds on a wide range of behaviors in a whole organism. A major challenge lies in the lack of knowledge about the bioavailability and pharmacodynamic effects of b
Externí odkaz:
https://doaj.org/article/54c9053e75814ac5bd2bfd79806650c1
Autor:
Jarosław Widelski, Natalia Kasica, Monika Maciąg, Simon Vlad Luca, Barbara Budzyńska, Dafina Fondai, Piotr Podlasz, Krystyna Skalicka-Woźniak
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8693 (2023)
Anxiety is one of the most common central nervous system disorders, affecting at least one-quarter of the worldwide population. The medications routinely used for the treatment of anxiety (mainly benzodiazepines) are a cause of addiction and are char
Externí odkaz:
https://doaj.org/article/12af6ed7e95b45159b9fd8f43c1fca47
Autor:
Nesrine S. El Sayed, Riham Salah El Dine, Barbara Budzyńska, Anna Boguszewska-Czubara, Jolanta Kotlińska
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/3946d7ae8bc4486684d97b550be36152
Autor:
Anna Michalicha, Anna Tomaszewska, Vladyslav Vivcharenko, Barbara Budzyńska, Magdalena Kulpa-Greszta, Dominika Fila, Robert Pązik, Anna Belcarz
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 8002 (2023)
In recent years, there has been a significant increase in interest in the use of curdlan, a naturally derived polymer, for medical applications. However, it is relatively inactive, and additives increasing its biomedical potential are required; for e
Externí odkaz:
https://doaj.org/article/2b02d225631947dca18ee0ed272db9a9
Publikováno v:
Biomolecules, Vol 13, Iss 3, p 405 (2023)
Drug abuse is a worldwide problem that leads to negative physical, mental, and economic consequences. Although pharmacological strategies for drug addiction management have been widely studied, therapeutic options with high efficacy and a low side-ef
Externí odkaz:
https://doaj.org/article/92008e56e13f4ac6a794f82c4a4d20a7