Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Barbara Borowa-Mazgaj"'
Autor:
Magdalena Niemira, Barbara Borowa-Mazgaj, Samuel B. Bader, Adrianna Moszyńska, Marcin Ratajewski, Kaja Karaś, Mirosław Kwaśniewski, Adam Krętowski, Zofia Mazerska, Ester M. Hammond, Anna Skwarska
Publikováno v:
Biomedicines, Vol 8, Iss 9, p 292 (2020)
The androgen receptor (AR) plays a critical role in prostate cancer (PCa) development and metastasis. Thus, blocking AR activity and its downstream signaling constitutes a major strategy for PCa treatment. Here, we report on the potent anti-PCa activ
Externí odkaz:
https://doaj.org/article/9885726c812f483fb11fc972b9426358
Autor:
Carl E. Cerniglia, Ivan Rusyn, Igor P. Pogribny, Levan Muskhelishvili, Sangeeta Khare, Greg R. Olson, Rose A Willett, Arun J. Sanyal, Volodymyr Tryndyak, Frederick A. Beland, Sharon A. Ross, Mark I. Avigan, Ralph E. Patton, Aline de Conti, Barbara Borowa-Mazgaj, Anna Watson
Publikováno v:
FASEB J
Interindividual variability and sexual dimorphisms in the development of nonalcoholic fatty liver disease (NAFLD) are still poorly understood. In the present study, male and female strains of Collaborative Cross (CC) mice were fed a high-fat and high
Publikováno v:
Archives of Toxicology. 93:3335-3344
The increasing number of man-made chemicals in the environment that may pose a carcinogenic risk emphasizes the need to develop reliable time- and cost-effective approaches for carcinogen detection. To address this issue, we have investigated the uti
Autor:
Leandro Jimenez, Igor P. Pogribny, Arun J. Sanyal, Mulugeta Seneshaw, Volodymyr Tryndyak, Stepan Melnyk, F. Mirshahi, Aline de Conti, Barbara Borowa-Mazgaj, Frederick A. Beland, Ivan Rusyn, Colleen R Steward
Publikováno v:
Toxicol Sci
Nonalcoholic fatty liver disease (NAFLD) is becoming a major etiological risk factor for hepatocellular carcinoma (HCC) in the United States and other Western countries. In this study, we investigated the role of gene-specific promoter cytosine DNA m
Autor:
Kaja Karaś, Adam Kretowski, Barbara Borowa-Mazgaj, Magdalena Niemira, Adrianna Moszyńska, Mirosław Kwaśniewski, Marcin Ratajewski, Ester M. Hammond, Samuel B. Bader, Zofia Mazerska, Anna Skwarska
Publikováno v:
Biomedicines
Volume 8
Issue 9
Biomedicines, Vol 8, Iss 292, p 292 (2020)
Volume 8
Issue 9
Biomedicines, Vol 8, Iss 292, p 292 (2020)
The androgen receptor (AR) plays a critical role in prostate cancer (PCa) development and metastasis. Thus, blocking AR activity and its downstream signaling constitutes a major strategy for PCa treatment. Here, we report on the potent anti-PCa activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f888d95a108bd1aeef693875b8831315
https://ora.ox.ac.uk/objects/uuid:a9504e6b-d527-4722-a6b6-9ff19dead429
https://ora.ox.ac.uk/objects/uuid:a9504e6b-d527-4722-a6b6-9ff19dead429
Autor:
Igor P. Pogribny, Colleen R Steward, Frederick A. Beland, Volodymyr Tryndyak, Barbara Borowa-Mazgaj
Publikováno v:
Archives of toxicology. 94(12)
Chronic exposure to inorganic arsenic is associated with a variety of adverse health effects, including lung, bladder, kidney, and liver cancer. Several mechanisms have been proposed for arsenic-induced tumorigenesis; however, insufficient knowledge
Autor:
Jerzy Konopa, Barbara Horowska, Grażyna Peszyńska-Sularz, Barbara Borowa-Mazgaj, Ewa Paluszkiewicz, Zofia Mazerska, Ewa Augustin, Jolanta Paradziej-Łukowicz
Publikováno v:
European journal of medicinal chemistry. 204
New promising unsymmetrical bisacridine derivatives (UAs), have been developed. Three groups including 36 compounds were synthesized by the condensation of 4-nitro or 4-methylacridinone, imidazoacridinone and triazoloacridinone derivatives with 1-nit
Autor:
Wanda Bodnar, Grace A. Chappell, Aline de Conti, Barbara Borowa-Mazgaj, Yu-Syuan Luo, David W. Threadgill, Igor P. Pogribny, Fred A. Wright, Kranti Konganti, Weihsueh A. Chiu, Ivan Rusyn, Lauren Lewis
Publikováno v:
Chemical research in toxicology. 32(5)
Metabolism of 1,3-butadiene, a known human and rodent carcinogen, results in formation of reactive epoxides, a key event in its carcinogenicity. Although mice exposed to 1,3-butadiene present DNA adducts in all tested tissues, carcinogenicity is limi
Autor:
Barbara Borowa-Mazgaj
Publikováno v:
Postępy Higieny i Medycyny Doświadczalnej, Vol 70, Pp 169-179 (2016)
Despite the enormous progress made over the past decades in diagnosis, treatment and prevention of many types of tumor, the survival rate for pancreatic cancer still remains poor. Pancreatic cancer is one of the most malignant and chemotherapy-resist
Autor:
Aiwei Yao-Borengasser, Randy S. Haun, Sebastian J. Pyrek, Barbara Borowa-Mazgaj, Tariq Fahmi, Susan Kadlubar, Peter I. Mackenzie, Anna Radominska-Pandya, Centdrika R. Dates, Stacie M. Bratton
Publikováno v:
Cancer Biology & Therapy. 16:714-723
Increased aerobic glycolysis and de novo lipid biosynthesis are common characteristics of invasive cancers. UDP-glucuronosyltransferases (UGTs) are phase II drug metabolizing enzymes that in normal cells possess the ability to glucuronidate these lip