Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Barbara A. Spengler"'
Autor:
Jeanette D. Walton, David R. Kattan, Sharon K. Thomas, Barbara A. Spengler, Hong-Fen Guo, June L. Biedler, Nai-Kong V. Cheung, Robert A. Ross
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 6, Iss 6, Pp 838-845 (2004)
Cellular heterogeneity is a hallmark of human neuroblastoma tumors and cell lines. Within a single neuroblastoma are cells from distinct neural crest lineages whose relative abundance is significant for prognosis. We postulate that a self-renewing mu
Externí odkaz:
https://doaj.org/article/3d82b77190214067a8f8a24165bf19e2
Publikováno v:
Oncology Reports
Neuroblastoma is a childhood cancer originating from embryonic neural crest cells. Amplification of the proto‑oncogene N-myc, seen in ~30% of neuroblastoma tumors, is a marker for poor prognosis. Recently discovered small regulatory RNAs, microRNAs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ebcf920c0b675aebce419dda89366e9
https://doi.org/10.3892/or.2017.5664
https://doi.org/10.3892/or.2017.5664
Autor:
Bernadette Léon, Marie-José Terrier-Lacombe, Gilbert M. Lenoir, Alexander Valent, Alain Bernheim, Dominique Valteau-Couanet, Jean Bénard, Michel Barrois, Barbara A. Spengler, Gwenaëlle Le Roux
Publikováno v:
The Journal of Pathology. 198:495-501
Neuroblastoma is the most frequent solid extracranial neoplasm of childhood, with a median age of presentation of under 2 years. This tumour is highly malignant in patients older than 12 months of age with metastatic disease. Clinical studies have co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d031b8b7535c445866f42539bbe0f3e
https://doi.org/10.1002/path.1244
https://doi.org/10.1002/path.1244
Autor:
Kristin D. Kisselbach, Sotiris N Nikolopoulos, Audrey E. Evans, Robert A. Ross, June L. Biedler, Barbara A. Spengler
Publikováno v:
Oncogene. 19:380-386
alpha-Actinins are actin-binding proteins important in organization of the cytoskeleton and in cell adhesion. We have cloned and characterized a cDNA from human neuroblastoma cell variants which encodes the second non-muscle alpha-actinin isoform des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64b1a3f742d4f3065d81e234bcdce43b
https://doi.org/10.1038/sj.onc.1203310
https://doi.org/10.1038/sj.onc.1203310
Autor:
Francis M. Sirotnak, Ching H. Yang, Berend Tolner, Judy H. Chiao, June L. Biedler, Barbara A. Spengler, Krishnendu Roy
Publikováno v:
Cancer Genetics and Cytogenetics. 105:29-38
A variant of the L1210 cell (L1210/R83) selected in the presence of the lipophilic antifolate, metoprine, and a concentration of the natural diastereoisomer of 5-formyltetrahydrofolate, lL5CHO-folateH4, suboptimum for growth exhibited a 35-fold incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9be33d6b42332998fdcef12664e4ce4a
https://doi.org/10.1016/s0165-4608(98)00005-3
https://doi.org/10.1016/s0165-4608(98)00005-3
Autor:
June L. Biedler, Barbara A. Spengler
Publikováno v:
Cancer and Metastasis Reviews. 13:191-207
Spontaneously transformed Chinese hamster lung cells with high levels of resistance (approximately 100-fold to 70,000-fold) to actinomycin D, daunorubicin, or vincristine exhibit morphology and growth patterns characteristic of normal cells in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cedaf9ba5d431a5aefd2a54b3d0a69f
https://doi.org/10.1007/bf00689636
https://doi.org/10.1007/bf00689636
Cellular heterogeneity is a well-known feature of human neuroblastoma tumors and cell lines. Of the 3 phenotypes (N-, I-, and S-type) isolated and characterized, the I-type cancer stem cell of neuroblastoma is the most malignant. Here, we report that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e572d606ce52fcc5d0c3d62149b6bcbe
https://europepmc.org/articles/PMC3379567/
https://europepmc.org/articles/PMC3379567/
Autor:
June L. Biedler, Michael P. LaQuaglia, Marian B. Meyers, Elizabeth B. Kopp, Barbara A. Spengler
Publikováno v:
Journal of Pediatric Surgery. 26:1107-1112
Neuroblastoma remains a significant problem in pediatric oncology. Recently a "multidrug-resistance" gene that may cause cells to become resistant to various chemotherapeutic agents has been cloned. The gene encodes the high-molecular-weight plasma m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fec823947f17f84a49474996ef98228b
https://doi.org/10.1016/0022-3468(91)90684-l
https://doi.org/10.1016/0022-3468(91)90684-l
Autor:
Robert A. Ross, Barbara A. Spengler
Publikováno v:
Journal of the National Cancer Institute. 96(16)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::302a9e219c52d1c04a170d34661492b0
https://pubmed.ncbi.nlm.nih.gov/15316056
https://pubmed.ncbi.nlm.nih.gov/15316056