Výsledky vyhledávání - "Barbara A. Broni"

Parental influenza virion nucleocapsids are efficiently transported into the nuclei of murine cells expressing the nuclear interferon-induced Mx protein

Autor: M. J. Berry, J. H. Condra, Robert M. Krug, Barbara A. Broni, Ilkka Julkunen, M. E. Davies

Publikováno v: Journal of Virology. 64:6335-6340

The interferon-induced murine Mx1 protein, which is localized in the nucleus, most likely specifically blocks influenza virus replication by inhibiting nuclear viral mRNA synthesis, including the mRNA synthesis catalyzed by inoculum (parental) virion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08e2a41dfc60d18d53028b022607d981
https://doi.org/10.1128/jvi.64.12.6335-6340.1990

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Influenza Virus Temperature-Sensitive Cap (m 7 GpppNm)-Dependent Endonuclease

Autor: Barbara A. Broni, Robert M. Krug, Ismo Ulmanen

Publikováno v: Journal of Virology. 45:27-35

The first step in influenza viral mRNA synthesis is the endonucleolytic cleavage of heterologous RNAs containing cap 1 (m 7 GpppNm) structures to generate capped primers that are 10 to 13 nucleotides long, which are then elongated to form the viral m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbcacf194152488569e3f2507ed122ca
https://doi.org/10.1128/jvi.45.1.27-35.1983

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Are the 5′ ends of influenza viral mrnas synthesized in vivo donated by host mRNAs?

Autor: Robert M. Krug, Barbara A. Broni, Michele Bouloy

Publikováno v: Cell. 18:329-334

Eucaryotic mRNAs serve as primers for influenza viral RNA transcription in vitro and donate their 5′ terminal methylated cap and a short stretch of internal nucleotides to the resulting viral RNA transcripts (Plotch, Bouloy and Krug, 1979). If a si

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee449cddc2020e0964c35d2d8f69a52
https://doi.org/10.1016/0092-8674(79)90052-7

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Role of two of the influenza virus core P proteins in recognizing cap 1 structures (m7GpppNm) on RNAs and in initiating viral RNA transcription

Autor: Robert M. Krug, Barbara A. Broni, Ismo Ulmanen

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 78(12)

Purified influenza viral cores catalyze the entire process of viral RNA transcription, which includes the endonucleolytic cleavage of heterologous RNAs containing cap 1 (m 7 GpppNm) structures to generate capped primers 10-13 nucleotides long, the in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e408b385fc88eecccc30bc14bde6b60
https://pubmed.ncbi.nlm.nih.gov/6950380

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Priming and inhibitory activities of RNAs for the influenza viral transcriptase do not require base pairing with the virion template RNA

Autor: Robert M. Krug, Alba J. Lafiandra, Barbara A. Broni, Maureen A. Morgan, Aaron J. Shatkin

Capped ribopolymers lacking a sequence complementary to the common 3' end of the influenza virion RNA segments effectively stimulated transcription of these RNAs by the virion-associated transcriptase. Thus, stimulation of transcription results not f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c19cfafb1e8f1fe32efcc892a4b59ce0
https://europepmc.org/articles/PMC350174/

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