Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Barbara A. Bohne"'
Autor:
John C. Sun, Adriaan M. van Alphen, Mariette Wagenaar, Patrick Huygen, Casper C. Hoogenraad, Tama Hasson, Sebastiaan K.E. Koekkoek, Barbara A. Bohne, Chris I. De Zeeuw
Publikováno v:
Neurobiology of Disease, Vol 8, Iss 1, Pp 69-77 (2001)
It is still debated to what extent the vestibular deficits in Usher patients are due to either central vestibulocerebellar or peripheral vestibular problems. Here, we determined the origin of the vestibular symptoms in Usher 1B patients by subjecting
Externí odkaz:
https://doaj.org/article/e15cc5fb6a5c47e79aa4273b2ef38a8d
Publikováno v:
Hearing Research. 344:158-169
From our permanent collection of plastic-embedded flat preparations of chinchilla cochleae, 22 controls and 199 ears from noise-exposed animals were used to determine when, postexposure, hair cell (HC) and supporting cell (SC) degeneration were compl
Autor:
Barbara A. Bohne, Gary W. Harding
Publikováno v:
Hearing Research. 254:54-63
In a previous study, we examined the relation between total energy in a noise exposure and the percentage losses of outer (OHC) and inner (IHC) hair cells in the basal and apical halves of 607 chinchilla cochleae [Harding, G.W., Bohne, B.A., 2004a. N
Autor:
Gary W. Harding, Barbara A. Bohne, William M. Landau, Kai Sun, Diego Torres-Russotto, P. M. Sinatra
Publikováno v:
Neurology. 72:1595-1600
Determination of auditory function is a fundamental part of a complete neurologic examination. Disability from permanent hearing loss is common in the general population. Current bedside auditory tests are unreliable and cumbersome. We evaluated the
Publikováno v:
The Open Otorhinolaryngology Journal. 2:29-43
Objective: To determine what death pathways are followed by noise-damaged outer hair cells (OHCs). Methods: Chinchillas were exposed to a 0.5-kHz octave band of noise for 24 h. Administration of trypan blue in vivo was used to stain nuclei in cells w
Publikováno v:
Hearing Research. 225:128-138
Infrasound (i.e.
Autor:
Barbara A. Bohne, Chris I. De Zeeuw, Patrick L. M. Huygen, M. Wagenaar, Tama Hasson, Sebastiaan K. E. Koekkoek, Casper C. Hoogenraad, Adriaan M. van Alphen, John C. Sun
Publikováno v:
Annals of the New York Academy of Sciences. 942:493-496
Identification of genes involved in hereditary vestibular disease is growing at a remarkable pace. Mutant mouse technology can be an important tool for understanding the biological mechanism of human vestibular diseases.
Publikováno v:
Hearing Research. 204:90-100
Inbred C57BL/6J mice carry two copies of an age-related hearing loss gene (Ahl). It has been shown that these mice begin losing high-frequency hearing at two months. Several functional studies have reported that the Ahl gene renders mice more suscept
Publikováno v:
Hearing Research. 175:82-100
An in vivo tracer was used to determine if the reticular lamina and/or the cell membranes abutting the endolymphatic space are temporarily disrupted after intense noise exposure (4-kHz OBN, 108-dB SPL, 1.75 h). Using a double-barreled micropipette, t