Zobrazeno 1 - 10
of 256
pro vyhledávání: '"Barbara A, Fox"'
Autor:
Claire M. Doherty, Paige R. Patterson, Julie A. Emeanuwa, Jessica Belmares Ortega, Barbara A. Fox, David J. Bzik, Eric Y. Denkers
Publikováno v:
mBio, Vol 15, Iss 11 (2024)
ABSTRACT As a model organism in the study of immunity to infection, Toxoplasma gondii has been instrumental in establishing key principles of host anti-microbial defense and its regulation. Here, we employed an attenuated uracil auxotroph strain of T
Externí odkaz:
https://doaj.org/article/e4fc1f9b3a5741efafd95bfc8cb21f30
Autor:
Hironori Bando, Yuho Murata, Yongmei Han, Tatsuki Sugi, Yasuhiro Fukuda, David J. Bzik, Barbara A. Fox, Kentaro Kato
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Toxoplasma, an important intracellular parasite of humans and animals, causes life-threatening toxoplasmosis in immunocompromised individuals. Although Toxoplasma secretory proteins during acute infection (tachyzoite, which divides rapidly and causes
Externí odkaz:
https://doaj.org/article/cc9abefb86524b48821386dd5e5ad8e4
Autor:
Joseph Lykins, Matthew J. Moschitto, Ying Zhou, Ekaterina V. Filippova, Hoang V. Le, Tadakimi Tomita, Barbara A. Fox, David J. Bzik, Chunlei Su, Seesandra V. Rajagopala, Kristin Flores, Furio Spano, Stuart Woods, Craig W. Roberts, Cong Hua, Kamal El Bissati, Kelsey M. Wheeler, Sarah Dovgin, Stephen P. Muench, Martin McPhillie, Colin W.G. Fishwick, Wayne F. Anderson, Patricia J. Lee, Mark Hickman, Louis M. Weiss, Jitender P. Dubey, Hernan A. Lorenzi, Richard B. Silverman, Rima L. McLeod
Publikováno v:
iScience, Vol 27, Iss 1, Pp 108477- (2024)
Summary: Toxoplasma gondii causes morbidity, mortality, and disseminates widely via cat sexual stages. Here, we find T. gondii ornithine aminotransferase (OAT) is conserved across phyla. We solve TgO/GABA-AT structures with bound inactivators at 1.55
Externí odkaz:
https://doaj.org/article/4214ce2e3d344bdb89d711a4b2786ce4
Autor:
Rajesh Mani, Mohamed H. Abdelaziz, Eri Ochiai, Qila Sa, Barbara A. Fox, David J. Bzik, Yasuhiro Suzuki
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Toxoplasma gondii establishes chronic infection by forming tissue cysts, and this chronic infection is one of the most common parasitic infections in humans. Our recent studies revealed that whereas CD8+ T cells of genetically resistant BALB/c mice h
Externí odkaz:
https://doaj.org/article/15463f22d29f4aff8abb0a9b91245bde
Publikováno v:
Frontiers in Communication, Vol 6 (2021)
This paper investigates the body’s role in grammar in argument sequences. Drawing from a database of public disputes on language use, we document the work of the palm-up gesture in action formation. Using conversation analysis and interactional lin
Externí odkaz:
https://doaj.org/article/387c2453ade34d2eb967040885e75492
Publikováno v:
mSphere, Vol 6, Iss 2 (2021)
If host immunity weakens, Toxoplasma gondii
Externí odkaz:
https://doaj.org/article/0b03429ca7d54605862d8bad9197a4d8
Autor:
Heather L Mercer, Lindsay M Snyder, Claire M Doherty, Barbara A Fox, David J Bzik, Eric Y Denkers
Publikováno v:
PLoS Pathogens, Vol 16, Iss 5, p e1008572 (2020)
The apicomplexan Toxoplasma gondii induces strong protective immunity dependent upon recognition by Toll-like receptors (TLR)11 and 12 operating in conjunction with MyD88 in the murine host. However, TLR11 and 12 proteins are not present in humans, i
Externí odkaz:
https://doaj.org/article/1158ee5894a54cd9af1900b0919a7d3c
Publikováno v:
mSphere, Vol 5, Iss 2 (2020)
ABSTRACT The glycosylated mucin domain of the Toxoplasma gondii cyst wall glycoprotein CST1 is heavily stained by Dolichos biflorus agglutinin, a lectin that binds to N-acetylgalactosamine. The cyst wall is also heavily stained by the chitin binding
Externí odkaz:
https://doaj.org/article/3201a1e697564c82876a056dde0c39f9
Publikováno v:
mSphere, Vol 5, Iss 1 (2020)
ABSTRACT After differentiation is triggered, the tachyzoite-stage Toxoplasma gondii parasitophorous vacuole membrane (PVM) has been hypothesized to transition into the cyst membrane that surrounds the cyst wall and encloses bradyzoites. Here, we trac
Externí odkaz:
https://doaj.org/article/3f45c4aa406b4e6eaf55482db85eaec7
Publikováno v:
Pragmatics. Quarterly Publication of the International Pragmatics Association (IPrA). :427-454
This study began with a simple question that has been on our minds, indMdually and collectively, for some time: What are the basic units of talk-in-conversation? Units in conversation must be understood as usable for the construction of joint activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55f1732865dca8a2422bd7e89c83c594
https://doi.org/10.1075/prag.6.3.07for
https://doi.org/10.1075/prag.6.3.07for