Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Barbara Spolaore"'
Autor:
Alejandro Montoya-Gómez, Fiorella Tonello, Barbara Spolaore, Maria Lina Massimino, Leonel Montealegre-Sánchez, Andrés Castillo, Nelson Rivera Franco, María José Sevilla-Sánchez, Luis Manuel Solano-Redondo, Mildrey Mosquera-Escudero, Eliécer Jiménez-Charris
Publikováno v:
Cells, Vol 12, Iss 23, p 2715 (2023)
Despite advances in chemotherapeutic drugs used against cervical cancer, available chemotherapy treatments adversely affect the patient’s quality of life. For this reason, new molecules from natural sources with antitumor potential and few side eff
Externí odkaz:
https://doaj.org/article/f4cfc9c7ead043b1ad5aea96659ec82a
Autor:
Daniele Peterle, Giulia Pontarollo, Stefano Spada, Paola Brun, Luana Palazzi, Alexej V. Sokolov, Barbara Spolaore, Patrizia Polverino de Laureto, Vadim B. Vasilyev, Ignazio Castagliuolo, Vincenzo De Filippis
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-14 (2020)
Peterle et al. show that a subtilisin like serine protease secreted from gut microbiota Bacillus subtilis cleaves the wild-type human transthyretin (hTTR) to generate an amyloidogenic peptide. High propensity of the hTTR fragment to form pathogenic p
Externí odkaz:
https://doaj.org/article/2199dcaae147423ba84acbd941b4fee7
Autor:
Barbara Spolaore, Luca Secco, Giulia Rocca, Guidalberto Manfioletti, Giorgio Arrigoni, Riccardo Sgarra
Publikováno v:
Expert Review of Proteomics. :1-15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::137a8b04ea7b04d3641cb19c8b704cf7
https://doi.org/10.1080/14789450.2023.2217359
https://doi.org/10.1080/14789450.2023.2217359
Autor:
Cristina Bolzati, Barbara Spolaore
Publikováno v:
Molecules, Vol 26, Iss 12, p 3492 (2021)
Site-specific conjugation of proteins is currently required to produce homogenous derivatives for medicine applications. Proteins derivatized at specific positions of the polypeptide chain can actually show higher stability, superior pharmacokinetics
Externí odkaz:
https://doaj.org/article/88d009137e9140a5b29c8e065516a792
Autor:
Cristina Bolzati, Nicola Salvarese, Barbara Spolaore, Andrea Vittadini, Daniel Forrer, Sara Brunello, Simona Ghiani, Alessandro Maiocchi
Publikováno v:
Molecular Pharmaceutics. 19:876-894
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c27679e445e0fcf158c390c329dd85f
https://doi.org/10.1021/acs.molpharmaceut.1c00816
https://doi.org/10.1021/acs.molpharmaceut.1c00816
Autor:
Silvia Ceschi, Michele Berselli, Marta Cozzaglio, Mery Giantin, Stefano Toppo, Barbara Spolaore, Claudia Sissi
Publikováno v:
Nucleic acids research. 50(3)
G-quadruplex (G4) structures that can form at guanine-rich genomic sites, including telomeres and gene promoters, are actively involved in genome maintenance, replication, and transcription, through finely tuned interactions with protein networks. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb314d03dff404bb0a2e0909748fa2c8
https://pubmed.ncbi.nlm.nih.gov/35100428
https://pubmed.ncbi.nlm.nih.gov/35100428
Autor:
Benedetta Fongaro, Elia Cappelletto, Alice Sosic, Barbara Spolaore, Patrizia Polverino de Laureto
Parkinson's disease (PD) is a chronic multifactorial disease, whose etiology is not completely understood. The amyloid aggregation of α-synuclein (Syn) is considered a major cause in the development of the disease. The presence of genetic mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e86b3cb22e325590f967778f33b5267d
http://hdl.handle.net/11577/3451218
http://hdl.handle.net/11577/3451218
Publikováno v:
Toxicon. 170:99-107
Almost all animal venoms contain secretory phospholipases A2 (PLA2s), 14 kDa disulfide-rich enzymes that hydrolyze membrane phospholipids at the sn-2 position, releasing lysophospholipids and fatty acids. These proteins, depending on their sequence,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2c18e6ff6c160d8cc6df149778c91a2
https://doi.org/10.1016/j.toxicon.2019.09.019
https://doi.org/10.1016/j.toxicon.2019.09.019
Autor:
Barbara Spolaore, Silvia Ceschi, Michele Berselli, Claudia Sissi, Stefano Toppo, Mery Giantin
G-quadruplex (G4) structures that can form at guanine-rich genomic sites, including telomeres and gene promoters, are actively involved in genome maintenance, replication, and transcription, through finely tuned interactions with protein networks. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20fb262fb5bca772774717bf6f75d833
https://doi.org/10.1101/2021.05.25.444966
https://doi.org/10.1101/2021.05.25.444966
Autor:
Cristina Bolzati, Nicola Salvarese, Barbara Spolaore, Sara Brunello, Simona Ghiani, Alessandro Maiocchi
Publikováno v:
Nuclear Medicine and Biology. :S147
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13b4df4e4344828024ae78fc4cffb309
https://doi.org/10.1016/s0969-8051(22)00315-8
https://doi.org/10.1016/s0969-8051(22)00315-8