Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Barbara, Wroblewska"'
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 367(1)
Glioma refers to malignant central nervous system tumors that have histologic characteristics in common with glial cells. The most prevalent type, glioblastoma multiforme, is associated with a poor prognosis and few treatment options. On the basis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cdbd847a0c2b37ae6379be55f05abbc
https://pubmed.ncbi.nlm.nih.gov/30054311
https://pubmed.ncbi.nlm.nih.gov/30054311
Autor:
Jarda T. Wroblewski, Eric J. Miller, Ewa Grajkowska, Carrie Bowman-Dalley, Dennis C. Liotta, Barry B. Wolfe, Barbara Wroblewska, Monica Javidnia, John O. DiRaddo
Publikováno v:
Molecular Pharmacology. 88:450-459
The elemental anion chloride is generally considered a passive participant in neuronal excitability, and has never been shown to function as an agonist in its own right. We show that the antagonist-mediated, glutamate-independent inverse agonism of g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fab4b75a3f48a8deb76826ae891a5d78
https://doi.org/10.1124/mol.114.096420
https://doi.org/10.1124/mol.114.096420
Publikováno v:
Acta Societatis Botanicorum Poloniae, Vol 57, Iss 1, Pp 149-155 (2014)
Roots of whole 3 week-old seedlings of maize were exposed for 24 h to a solution of PbCl2. The concentrations of Pb were: 0, 200, 400, 800, 1200, 2400 mg dm-3. The amount of Pb taken up by roots was independent of the concentration of this element in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25d7045d386aad4feec0f291fff07e3c
https://doi.org/10.5586/asbp.1988.014
https://doi.org/10.5586/asbp.1988.014
Autor:
Barbara Wroblewska, David A. Lewis
Publikováno v:
American Journal of Psychiatry. 166:753-756
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61b19c3541302b1c3168f073d6e9dff9
https://doi.org/10.1176/appi.ajp.2009.09040522
https://doi.org/10.1176/appi.ajp.2009.09040522
Autor:
Jia Zhou, Tatsuo Yamamoto, Tomasz Bzdega, Tomohiko Aoe, Alessandra Bartolozzi, Alan P. Kozikowski, Osamu Saito, Joseph H. Neale, Jayaprakash Sarva, Barbara Wroblewska
Publikováno v:
European Journal of Neuroscience. 25:147-158
The peptide neurotransmitter N-acetylaspartylglutamate (NAAG) selectively activates group II metabotropic glutamate receptors (mGluRs). Systemic administration of inhibitors of the enzymes that inactivate NAAG results in decreased pain responses in r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::165694d7450af56b79d922c835b87750
https://doi.org/10.1111/j.1460-9568.2006.05272.x
https://doi.org/10.1111/j.1460-9568.2006.05272.x
Publikováno v:
Journal of Neurochemistry. 90:989-997
The peptide transmitter N-acetylaspartylglutamate (NAAG) is present in millimolar concentrations in mammalian spinal cord. Data from the rat peripheral nervous system suggest that this peptide is synthesized enzymatically, a process that would be uni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d341468ad445052f1ba655d90d07230
https://doi.org/10.1111/j.1471-4159.2004.02578.x
https://doi.org/10.1111/j.1471-4159.2004.02578.x
Autor:
Jia Zhou, Alan P. Kozikowski, Barbara Wroblewska, Tatsuo Yamamoto, Joseph H. Neale, Serabi Hirasawa, Jarda T. Wroblewski, Ewa Grajkowska
Publikováno v:
European Journal of Neuroscience. 20:483-494
The peptide neurotransmitter N-acetylaspartylglutamate (NAAG) acts as an agonist at group II metabotropic glutamate receptors (mGluRs). NAAG is inactivated by extracellular peptidase activity yielding glutamate and N-acetylaspartate. We recently deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::046bd2f7d295714e005304308526521b
https://doi.org/10.1111/j.1460-9568.2004.03504.x
https://doi.org/10.1111/j.1460-9568.2004.03504.x
Autor:
Joseph H. Neale, Epolia R. Ramadan, Kathryn H. Sciarretta, Tomasz Bzdega, Barbara Wroblewska, Victoria A. Rafalski, Rafal T. Olszewski, Olumide A. Ojeifo, Samantha L. Crowe
Publikováno v:
Journal of Neurochemistry. 89:627-635
The peptide neurotransmitter N-acetylaspartylglutamate is inactivated by extracellular peptidase activity following synaptic release. It is speculated that the enzyme, glutamate carboxypeptidase II (GCPII, EC 3.14.17.21), participates in this inactiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b93d4e8389d8fe7f381ad2463efca1d7
https://doi.org/10.1111/j.1471-4159.2004.02361.x
https://doi.org/10.1111/j.1471-4159.2004.02361.x
Autor:
Joseph H. Neale, Alan P. Kozikowski, Fajun Nan, Jiazhong Zhang, Barbara Wroblewska, Tomasz Bzdega, Ewa Grajkowska, Pavel A. Petukhov, Tatsuo Yamamoto, Jarda T. Wroblewski
Publikováno v:
Journal of Medicinal Chemistry. 47:1729-1738
The neuropeptidase glutamate carboxypeptidase II (GCPII) hydrolyzes N-acetyl-L-aspartyl-L-glutamate (NAAG) to liberate N-acetylaspartate and glutamate. GCPII was originally cloned as PSMA, an M(r) 100,000 type II transmembrane glycoprotein highly exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d3bd04e908592fbd0959871b3d17ca
https://doi.org/10.1021/jm0306226
https://doi.org/10.1021/jm0306226
Autor:
Angel L. De Blas, Barbara Wroblewska, Lorenzo Corsi, Dennis R. Grayson, Subroto Ghose, Joseph H. Neale, Stefano Vicini
Publikováno v:
Journal of Neurochemistry. 69:2326-2335
We have shown that the vertebrate neuropeptide N-acetylaspartylglutamate (NAAG) meets the criteria for a neurotransmitter, including function as a selective metabotropic glutamate receptor (mGluR) 3 agonist. Short-term treatment of cerebellar granule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef3416fc771d2cc32640ba288f25883e
https://doi.org/10.1046/j.1471-4159.1997.69062326.x
https://doi.org/10.1046/j.1471-4159.1997.69062326.x