Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Barbara, Rolando"'
Autor:
Monica Cozzi, Mariacristina Failla, Eleonora Gianquinto, Sandra Kovachka, Valeria Buoli Comani, Carlotta Compari, Omar De Bei, Roberta Giaccari, Francesco Marchesani, Marialaura Marchetti, Luca Ronda, Barbara Rolando, Massimo Baroni, Gabriele Cruciani, Barbara Campanini, Stefano Bettati, Serena Faggiano, Loretta Lazzarato, Francesca Spyrakis
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-21 (2024)
Abstract Human hemoglobin (Hb) is the preferred iron source of Staphylococcus aureus. This pathogenic bacterium exploits a sophisticated protein machinery called Iron-regulated surface determinant (Isd) system to bind Hb, extract and internalize heme
Externí odkaz:
https://doaj.org/article/f9ef68fdb4844b4a8556175d108cfb76
Autor:
Claudia Cristiano, Robert J. Cavanagh, Valentina Cuzzucoli Crucitti, Cara Moloney, Eleni Axioti, Emily Dixon, Philippa L. Jacob, Marica Erminia Schiano, Mariarosaria Cuozzo, Fabrizio Maria Liguori, Barbara Rolando, Roberto Russo, Vincenzo Taresco, Federica Sodano, Maria Grazia Rimoli
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 175, Iss , Pp 116647- (2024)
Objective: To improve the biological and toxicological properties of Mefenamic acid (MA), the galactosylated prodrug of MA named MefeGAL was included in polymeric solid dispersions (PSs) composed of poly(glycerol adipate) (PGA) and Pluronic® F68 (Me
Externí odkaz:
https://doaj.org/article/db93440f78ef45dca4992d06a234c3dd
Autor:
Tiago M. A. Carvalho, Madelaine Magalì Audero, Maria Raffaella Greco, Marilena Ardone, Teresa Maggi, Rosanna Mallamaci, Barbara Rolando, Silvia Arpicco, Federico Alessandro Ruffinatti, Alessandra Fiorio Pla, Natalia Prevarskaya, Tomas Koltai, Stephan J. Reshkin, Rosa Angela Cardone
Publikováno v:
Cells, Vol 13, Iss 9, p 730 (2024)
Background: Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease with high mortality due to early metastatic dissemination and high chemoresistance. All these factors are favored by its extracellular matrix (ECM)-rich microenvironment, which i
Externí odkaz:
https://doaj.org/article/359ae37a40954942bc5f86182bbda81f
Autor:
Angela Corvino, Valentina Citi, Ferdinando Fiorino, Francesco Frecentese, Elisa Magli, Elisa Perissutti, Vincenzo Santagada, Vincenzo Calderone, Alma Martelli, Era Gorica, Simone Brogi, Flavia Faganello Colombo, Caroline Nunes Capello, Heloisa Helena Araujo Ferreira, Maria Grazia Rimoli, Federica Sodano, Barbara Rolando, Francesca Pavese, Antonio Petti, Marcelo Nicolás Muscará, Giuseppe Caliendo, Beatrice Severino
Publikováno v:
Journal of Advanced Research, Vol 35, Iss , Pp 267-277 (2022)
Introduction: Hydrogen sulfide (H2S) is a fundamental biological endogenous gas-mediator in the respiratory system. It regulates pivotal patho-physiological processes such as oxidative stress, pulmonary circulation, airway tone and inflammation. Obje
Externí odkaz:
https://doaj.org/article/610e9a0c8bd745389a68efd1fc4472d6
Autor:
Loretta Lazzarato, Laura Bianchi, Annapaola Andolfo, Agnese Granata, Matteo Lombardi, Matteo Sinelli, Barbara Rolando, Marina Carini, Alberto Corsini, Roberta Fruttero, Lorenzo Arnaboldi
Publikováno v:
Molecules, Vol 28, Iss 15, p 5724 (2023)
Physiologically, smooth muscle cells (SMC) and nitric oxide (NO) produced by endothelial cells strictly cooperate to maintain vasal homeostasis. In atherosclerosis, where this equilibrium is altered, molecules providing exogenous NO and able to inhib
Externí odkaz:
https://doaj.org/article/5242d759d14f4a8884041774b0f83b09
Autor:
Federica Sodano, Barbara Rolando, Loretta Lazzarato, Costanzo Costamagna, Mariacristina Failla, Chiara Riganti, Konstantin Chegaev
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11258 (2023)
The application of gaseous signaling molecules like NO, H2S or CO to overcome the multidrug resistance in cancer treatment has proven to be a viable therapeutic strategy. The development of CO-releasing molecules (CORMs) in a controlled manner and in
Externí odkaz:
https://doaj.org/article/bf7be03b922c4f91a0e389094eabac29
Autor:
Elisabetta Marini, Barbara Rolando, Federica Sodano, Federica Blua, Giulia Concina, Stefano Guglielmo, Loretta Lazzarato, Konstantin Chegaev
Publikováno v:
Antioxidants, Vol 12, Iss 2, p 344 (2023)
In the last years, research proofs have confirmed that hydrogen sulfide (H2S) plays an important role in various physio-pathological processes, such as oxidation, inflammation, neurophysiology, and cardiovascular protection; in particular, the protec
Externí odkaz:
https://doaj.org/article/67df7739e749437abb9a730a210939a0
Autor:
Elisabetta Marini, Marco Marino, Giulia Gionfriddo, Federica Maione, Marta Pandini, Daniele Oddo, Marta Giorgis, Barbara Rolando, Federica Blua, Simone Gastaldi, Serena Marchiò, Sandra Kovachka, Francesca Spyrakis, Eleonora Gianquinto, Federica Di Nicolantonio, Massimo Bertinaria
Publikováno v:
Molecules, Vol 27, Iss 23, p 8513 (2022)
BRAF is a serine/threonine kinase frequently mutated in human cancers. BRAFV600E mutated protein is targeted through the use of kinase inhibitors which are approved for the treatment of melanoma; however, their long-term efficacy is hampered by resis
Externí odkaz:
https://doaj.org/article/321ff11884e9491784732a391526bf64
Autor:
Eleonora Gianquinto, Federica Sodano, Barbara Rolando, Magdalena Kostrzewa, Marco Allarà, Ali Mokhtar Mahmoud, Poulami Kumar, Francesca Spyrakis, Alessia Ligresti, Konstantin Chegaev
Publikováno v:
Molecules, Vol 27, Iss 23, p 8152 (2022)
Cannabinoid type 1 (hCB1) and type 2 (hCB2) receptors are pleiotropic and crucial targets whose signaling contributes to physiological homeostasis and its restoration after injury. Being predominantly expressed in peripheral tissues, hCB2R represents
Externí odkaz:
https://doaj.org/article/30fb8dde4c70493698c84d4204fa91ed
Autor:
Federica Sodano, Claudia Cristiano, Barbara Rolando, Elisabetta Marini, Loretta Lazzarato, Mariarosaria Cuozzo, Stefania Albrizio, Roberto Russo, Maria Grazia Rimoli
Publikováno v:
Pharmaceuticals, Vol 15, Iss 5, p 552 (2022)
Carbohydrates are one of the most abundant and important classes of biomolecules. The variety in their structures makes them valuable carriers that can improve the pharmaceutical phase, pharmacokinetics and pharmacodynamics of well-known drugs. D-gal
Externí odkaz:
https://doaj.org/article/a838976e668644c4b53f8b0f120dcfdb