Zobrazeno 1 - 10
of 208
pro vyhledávání: '"Barbara, Mulloy"'
Autor:
Christina Nikolova, Gordon Morris, David Ellis, Bernard Bowler, Martin Jones, Barbara Mulloy, Tony Gutierrez
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0299235 (2024)
In this study, we characterize the exopolymer produced by Halomonas sp. strain TGOS-10 -one of the organisms found enriched in sea surface oil slicks during the Deepwater Horizon oil spill. The polymer was produced during the early stationary phase o
Externí odkaz:
https://doaj.org/article/5e9f3b1b74eb4d99b5debd40743926c5
Publikováno v:
Communications Chemistry, Vol 4, Iss 1, Pp 1-8 (2021)
Glycosaminoglycans are an important class of carbohydrates, but pose substantial analytical challenges. Here ToF-SIMS combined with multivariate analysis distinguishes six classes of glycosaminoglycans, including distinguishing heparin samples from d
Externí odkaz:
https://doaj.org/article/c121f4f95c754304b98a4975451b0470
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 271 (2023)
Sepsis is a life-threatening hyperreaction to infection in which excessive inflammatory and immune responses cause damage to host tissues and organs. The glycosaminoglycan heparan sulphate (HS) is a major component of the cell surface glycocalyx. Cel
Externí odkaz:
https://doaj.org/article/3ec59c7d84ce44ec8bc7a1e215d3da96
Autor:
Viviana G. Correia, Filipa Trovão, Benedita A. Pinheiro, Joana L. A. Brás, Lisete M. Silva, Cláudia Nunes, Manuel A. Coimbra, Yan Liu, Ten Feizi, Carlos M. G. A. Fontes, Barbara Mulloy, Wengang Chai, Ana Luísa Carvalho, Angelina S. Palma
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 3 (2021)
ABSTRACT A multigene polysaccharide utilization locus (PUL) encoding enzymes and surface carbohydrate (glycan)-binding proteins (SGBPs) was recently identified in prominent members of Bacteroidetes in the human gut and characterized in Bacteroides ov
Externí odkaz:
https://doaj.org/article/24f151b72651473cb81a3329848e3bea
Publikováno v:
Pharmacological Reviews. 75:328-379
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1036500a36d843f47920463e8c65a719
https://doi.org/10.1124/pharmrev.122.000684
https://doi.org/10.1124/pharmrev.122.000684
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Externí odkaz:
https://doaj.org/article/85adde71a0984296b09654345898ee0b
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0233644 (2020)
Cytotoxic and pro-inflammatory histones are present in neutrophil extracellular traps (NETs) and are elevated in blood in several inflammatory conditions, sepsis being a major example. Compounds which can attenuate activities of histones are therefor
Externí odkaz:
https://doaj.org/article/0c2b04de83904a59bbd09e14052c1bf9
Autor:
Hong Li, Michael Marceau, Tiandi Yang, Tingting Liao, Xiaoqiong Tang, Renwei Hu, Yan Xie, Hong Tang, Alfred Tay, Ying Shi, Yalin Shen, Tiankuo Yang, Xuenan Pi, Binit Lamichhane, Yong Luo, Aleksandra W Debowski, Hans-Olof Nilsson, Stuart M Haslam, Barbara Mulloy, Anne Dell, Keith A Stubbs, Barry J Marshall, Mohammed Benghezal
Publikováno v:
PLoS Genetics, Vol 15, Iss 11, p e1008497 (2019)
The lipopolysaccharide O-antigen structure expressed by the European Helicobacter pylori model strain G27 encompasses a trisaccharide, an intervening glucan-heptan and distal Lewis antigens that promote immune escape. However, several gaps still rema
Externí odkaz:
https://doaj.org/article/7035fb36819a4999b96963d7d7cbb754
Autor:
Bryan E. Thacker, Kristen J. Thorne, Colin Cartwright, Jeeyoung Park, Kimberly Glass, Annie Chea, Benjamin P. Kellman, Nathan E. Lewis, Zhenping Wang, Anna Di Nardo, Susan T. Sharfstein, Walter Jeske, Jeanine Walenga, John Hogwood, Elaine Gray, Barbara Mulloy, Jeffrey D. Esko, Charles A. Glass
Publikováno v:
Metabolic Engineering. 70:155-165
Heparin is an essential anticoagulant used for treating and preventing thrombosis. However, the complexity of heparin has hindered the development of a recombinant source, making its supply dependent on a vulnerable animal population. In nature, hepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca4eb39db7acb0dc166acf6cadcd29e8
https://doi.org/10.1016/j.ymben.2022.01.002
https://doi.org/10.1016/j.ymben.2022.01.002
Autor:
Hong Li, Tiandi Yang, Tingting Liao, Aleksandra W Debowski, Hans-Olof Nilsson, Alma Fulurija, Stuart M Haslam, Barbara Mulloy, Anne Dell, Keith A Stubbs, Barry J Marshall, Mohammed Benghezal
Publikováno v:
PLoS Pathogens, Vol 13, Iss 3, p e1006280 (2017)
Helicobacter pylori lipopolysaccharide promotes chronic gastric colonisation through O-antigen host mimicry and resistance to mucosal antimicrobial peptides mediated primarily by modifications of the lipid A. The structural organisation of the core a
Externí odkaz:
https://doaj.org/article/b33a1eda4f5f4c76be7e5645dd23e307