Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Barbara, Mordyl"'
Autor:
Izabella Góral, Tomasz Wichur, Emilia Sługocka, Justyna Godyń, Natalia Szałaj, Paula Zaręba, Monika Głuch-Lutwin, Barbara Mordyl, Dawid Panek, Anna Więckowska
Publikováno v:
Molecules, Vol 29, Iss 11, p 2616 (2024)
GSK-3β, IKK-β, and ROCK-1 kinases are implicated in the pathomechanism of Alzheimer’s disease due to their involvement in the misfolding and accumulation of amyloid β (Aβ) and tau proteins, as well as inflammatory processes. Among these kinases
Externí odkaz:
https://doaj.org/article/d794b4a155cb4c9da646e809bc8a5781
Autor:
Grzegorz Kazek, Monika Głuch-Lutwin, Barbara Mordyl, Elżbieta Menaszek, Monika Kubacka, Anna Jurowska, Dariusz Cież, Bartosz Trzewik, Janusz Szklarzewicz, Monika A. Papież
Publikováno v:
Pharmaceuticals, Vol 17, Iss 2, p 229 (2024)
In the text, the synthesis and characteristics of the novel ONS-type vanadium (V) complexes with thioanilide derivatives of amino acids are described. They showed the inhibition of human protein tyrosine phosphatases (PTP1B, LAR, SHP1, and SHP2) in t
Externí odkaz:
https://doaj.org/article/12c73147d33048dbb272b70c13fc6acf
Autor:
Michał Załuski, Tadeusz Karcz, Anna Drabczyńska, Christin Vielmuth, Agnieszka Olejarz-Maciej, Monika Głuch-Lutwin, Barbara Mordyl, Agata Siwek, Grzegorz Satała, Christa E. Müller, Katarzyna Kieć-Kononowicz
Publikováno v:
Biomolecules, Vol 13, Iss 7, p 1079 (2023)
Multitarget drugs based on a hybrid dopamine–xanthine core were designed as potential drug candidates for the treatment of neurodegenerative diseases. Monoamine oxidase B (MAO-B) inhibitors with significant ancillary A2A adenosine receptor (A2AAR)
Externí odkaz:
https://doaj.org/article/a763a392789d4e87855485b3273ec76a
Autor:
Elżbieta Żmudzka, Klaudia Lustyk, Monika Głuch-Lutwin, Barbara Mordyl, Alicja Zakrzewska-Sito, Paweł Mierzejewski, Jolanta Jaśkowska, Marcin Kołaczkowski, Jacek Sapa, Karolina Pytka
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 15929 (2022)
Schizophrenia is a chronic mental illness, which remains difficult to treat. A high resistance to the available therapies, their insufficient efficacy, and numerous side effects are the reasons why there is an urgent need to develop new antipsychotic
Externí odkaz:
https://doaj.org/article/0b286050b9a844048be66d18514d16f1
Autor:
Hasan Shabbir, Konrad Wojtaszek, Bogdan Rutkowski, Edit Csapó, Marek Bednarski, Anita Adamiec, Monika Głuch-Lutwin, Barbara Mordyl, Julia Druciarek, Magdalena Kotańska, Piotr Ozga, Marek Wojnicki
Publikováno v:
Molecules, Vol 27, Iss 24, p 8728 (2022)
Carbon dots (CDs) are carbon-based zero-dimensional nanomaterials that can be prepared from a number of organic precursors. In this research, they are prepared using fat-free UHT cow milk through the hydrothermal method. FTIR analysis shows C=O and C
Externí odkaz:
https://doaj.org/article/d4435f8bfd52422db790d271cb548e54
Autor:
Dominik Straszak, Agata Siwek, Monika Głuch-Lutwin, Barbara Mordyl, Marcin Kołaczkowski, Aldona Pietrzak, Mansur Rahnama-Hezavah, Bartłomiej Drop, Dariusz Matosiuk
Publikováno v:
Molecules, Vol 27, Iss 9, p 2930 (2022)
The μ-opioid receptors belong to the family of G protein-coupled receptors (GPCRs), and their activation triggers a cascade of intracellular relays with the final effect of analgesia. Classical agonists of this receptor, such as morphine, are the ma
Externí odkaz:
https://doaj.org/article/0b660b25dfb14eb68e57adfc02e29837
Autor:
Monika Marcinkowska, Nikola Fajkis-Zajączkowska, Katarzyna Szafrańska, Jakub Jończyk, Agata Siwek, Barbara Mordyl, Tadeusz Karcz, Gniewomir Latacz, Marcin Kolaczkowski
Publikováno v:
ACS Chemical Neuroscience. 14:1166-1180
Autor:
Kieć-Kononowicz, Michał Załuski, Tadeusz Karcz, Anna Drabczyńska, Christin Vielmuth, Agnieszka Olejarz-Maciej, Monika Głuch-Lutwin, Barbara Mordyl, Agata Siwek, Grzegorz Satała, Christa E. Müller, Katarzyna
Publikováno v:
Biomolecules; Volume 13; Issue 7; Pages: 1079
Multitarget drugs based on a hybrid dopamine–xanthine core were designed as potential drug candidates for the treatment of neurodegenerative diseases. Monoamine oxidase B (MAO-B) inhibitors with significant ancillary A2A adenosine receptor (A2AAR)
Autor:
Anna Partyka, Agnieszka Zagórska, Magdalena Kotańska, Maria Walczak, Magdalena Jastrzębska-Więsek, Joanna Knutelska, Marek Bednarski, Monika Głuch-Lutwin, Barbara Mordyl, Paulina Janiszewska, Anna Wesołowska
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0237196 (2020)
Current antidepressant therapy has several disadvantages related to the properties of antidepressants. Considering their unfavourable features, the process of searching for new antidepressant drugs with better safety and tolerability requires consist
Externí odkaz:
https://doaj.org/article/5031bbd953be4b08bd829a539d4f8f98
Autor:
Sylwia Sudoł, Agnieszka Cios, Magdalena Jastrzębska-Więsek, Ewelina Honkisz-Orzechowska, Barbara Mordyl, Natalia Wilczyńska-Zawal, Grzegorz Satała, Katarzyna Kucwaj-Brysz, Anna Partyka, Gniewomir Latacz, Agnieszka Olejarz-Maciej, Anna Wesołowska, Jadwiga Handzlik
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10773 (2021)
Among the serotonin receptors, one of the most recently discovered 5-HT6 subtype is an important protein target and its ligands may play a key role in the innovative treatment of cognitive disorders. However, none of its selective ligands have reache
Externí odkaz:
https://doaj.org/article/91670653700945c1a6b4e2f80b99697f