TGFβ-signaling in Squamous Cell Carcinoma Occurring in Recessive Dystrophic Epidermolysis Bullosa

Autor: Julia Knaup, Christina Gruber, Barbara Krammer, Verena Ziegler, Johann Bauer, Thomas Verwanger

Publikováno v: Analytical Cellular Pathology, Vol 34, Iss 6, Pp 339-353 (2011)

Background: Recessive dystrophic epidermolysis bullosa (RDEB) is a hereditary skin disorder characterized by mechanical fragility of the skin, resulting in blistering and chronic wounds. The causative mutations lie in the COL7A1 gene. Patients suffer

Externí odkaz: https://doaj.org/article/3f01d14070bd48faa72f8a71680bf982

Targeting of a Helix-Loop-Helix Transcriptional Regulator by a Short Helical Peptide

Autor: Thomas Verwanger, Cornelia Roschger, Mario Schubert, Barbara Krammer, Brigitta Elsässer, Chiara Cabrele, Nicole Maeding, Saskia Neukirchen

Publikováno v: ChemMedChem. 12:1497-1503

The Id proteins (Id1-4) are cell-cycle regulators that play a key role during development, in cancer and vascular disorders. They contain a conserved helix-loop-helix (HLH) domain that folds into a parallel four-helix bundle upon self- or hetero-asso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::736308df01c90321d6eda8803e90e492
https://doi.org/10.1002/cmdc.201700305

Mechanically Strong Silica-Silk Fibroin Bioaerogel: A Hybrid Scaffold with Ordered Honeycomb Micromorphology and Multiscale Porosity for Bone Regeneration

Autor: Barbara Krammer, Sanjay Mathur, Stefan Zaunschirm, Barbara Milow, Susan Montes, Mohammad Reza Eskandari, Seyed Hojjat Hosseini, Hajar Maleki, Nicola Hüsing, Mohammad-Ali Shahbazi, Thomas Verwanger

Publikováno v: Maleki, H, Shahbazi, M-A, Montes, S, Hosseini, S H, Eskandari, M R, Zaunschirm, S, Verwanger, T, Mathur, S, Milow, B, Krammer, B & Hüsing, N 2019, ' Mechanically Strong Silica-Silk Fibroin Bioaerogel: A Hybrid Scaffold with Ordered Honeycomb Micromorphology and Multiscale Porosity for Bone Regeneration ', ACS Applied Materials and Interfaces, vol. 11, no. 19, pp. 17256-17269 . https://doi.org/10.1021/acsami.9b04283

Due to the synergic feature of individual components in hybrid (nano)biomaterials, their application in regenerative medicine has drawn significant attention. Aiming to address all the current challenges of aerogel as a potent scaffold in bone tissue

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::421e508b34a404298cd842f63ab19e2e
https://pubmed.ncbi.nlm.nih.gov/31013056

Development of curcumin-loaded gemini surfactant nanoparticles: Synthesis, characterization and evaluation of anticancer activity against human breast cancer cell lines

Autor: Mohammad Ali Hosseinpour Feizi, Thomas Verwanger, Mina Karimpour, Farhood Najafi, Majid Mahdavi, Esmaeil Babaei, Barbara Krammer

Publikováno v: Phytomedicine : international journal of phytotherapy and phytopharmacology. 57

Background Curcumin, the polyphenolic constituent of turmeric, has been recognized as an effective anticancer agent in the treatment of breast cancer. However, the poor bioavailability of curcumin triggers finding of new approaches for elevating its

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebdfc3e0719b232a41605e3e083dde8d
https://pubmed.ncbi.nlm.nih.gov/30776589

Influence of ALA-mediated photodynamic therapy on secretion of interleukins 6, 8 and 10 by colon cancer cells in vitro

Autor: Aleksandra Kawczyk-Krupka, Aleksander Sieroń, Katarzyna Wasilewska, Zenon P. Czuba, Barbara Krammer, Thomas Verwanger, Wojciech Latos

Publikováno v: Photodiagnosis and photodynamic therapy. 22

Background Photodynamic therapy has apart from a direct cytotoxic effect also immunomodulatory properties. The aim of our study was to investigate how photodynamic therapy with 5-aminolevulinic acid (ALA-PDT) in sublethal doses influences the secreti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebfdcf15d9199fdbce2d49c37a13693e
https://pubmed.ncbi.nlm.nih.gov/29510260