Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Barbara, Hrdlickova"'
Autor:
Zuzana Koledova, Jakub Sumbal, Anas Rabata, Gabin de La Bourdonnaye, Radka Chaloupkova, Barbara Hrdlickova, Jiri Damborsky, Veronika Stepankova
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Fibroblast growth factor 2 (FGF2) plays important roles in tissue development and repair. Using heparan sulfates (HS)/heparin as a cofactor, FGF2 binds to FGF receptor (FGFR) and induces downstream signaling pathways, such as ERK pathway, that regula
Externí odkaz:
https://doaj.org/article/08938c2cd7fe478bb520b88f23bf59da
Autor:
Subhash K. Tripathi, Zhi Chen, Antti Larjo, Kartiek Kanduri, Kari Nousiainen, Tarmo Äijo, Isis Ricaño-Ponce, Barbara Hrdlickova, Soile Tuomela, Essi Laajala, Verna Salo, Vinod Kumar, Cisca Wijmenga, Harri Lähdesmäki, Riitta Lahesmaa
Publikováno v:
Cell Reports, Vol 19, Iss 9, Pp 1888-1901 (2017)
The development of therapeutic strategies to combat immune-associated diseases requires the molecular mechanisms of human Th17 cell differentiation to be fully identified and understood. To investigate transcriptional control of Th17 cell differentia
Externí odkaz:
https://doaj.org/article/d673990638a54d0f83990621f297efa2
Autor:
Vinod Kumar, Harm-Jan Westra, Juha Karjalainen, Daria V Zhernakova, Tõnu Esko, Barbara Hrdlickova, Rodrigo Almeida, Alexandra Zhernakova, Eva Reinmaa, Urmo Võsa, Marten H Hofker, Rudolf S N Fehrmann, Jingyuan Fu, Sebo Withoff, Andres Metspalu, Lude Franke, Cisca Wijmenga
Publikováno v:
PLoS Genetics, Vol 9, Iss 1, p e1003201 (2013)
Recently it has become clear that only a small percentage (7%) of disease-associated single nucleotide polymorphisms (SNPs) are located in protein-coding regions, while the remaining 93% are located in gene regulatory regions or in intergenic regions
Externí odkaz:
https://doaj.org/article/754426b55bd74349994c444c81270ced
Publikováno v:
Biochimica et biophysica acta. 1842(10)
It has been found that the majority of disease-associated genetic variants identified by genome-wide association studies are located outside of protein-coding regions, where they seem to affect regions that control transcription (promoters, enhancers