Zobrazeno 1 - 10
of 248
pro vyhledávání: '"Barbara, Hero"'
Autor:
Daniela Di Carlo, Giulia Fichera, Benoit Dumont, Enrico Pozzo, Beate Timmermann, Romain Luscan, Antoine Moya-Plana, Anna Synakiewicz, Ewa Bien, Nino Jorge dos Reis Farinha, Malgorzata Krawczyk, Rita Alaggio, Apostolos Pourtsidis, Brice Fresneau, Yves Reguerre, Tal Ben-Ami, Calogero Virgone, Jelena Roganovic, Jan Godzinski, Ines B Brecht, Dominik Schneider, Andrea Ferrari, Barbara Hero, Daniel Orbach, Gianni Bisogno
Publikováno v:
EJC Paediatric Oncology, Vol 3, Iss , Pp 100136- (2024)
Olfactory neuroblastoma (ON) is a rare tumor commonly presenting between 50 and 60 years of age. In pediatric age this tumor is even rarer, with an estimated incidence of 0.1 per 100,000 children up to 15 years. It arises from the olfactory neurorepi
Externí odkaz:
https://doaj.org/article/63347801e0a243b0bc1bc645d4cb7d88
Autor:
Ahmed Farrag, Mohamed Hamdy Ghazaly, Khaled Mohammed, Ruth Volland, Barbara Hero, Frank Berthold
Publikováno v:
BMC Pediatrics, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Substantial progress has been achieved in managing childhood cancers in many high-income countries (HICs). In contrast, survival rates in lower-middle-income countries (LMICs) are less favorable. Here, we aimed to compare outcomes
Externí odkaz:
https://doaj.org/article/f669edb4b9a44548a6b047f1ee8d9034
Autor:
Danny Jazmati, Barbara Hero, Theresa M. Thole.-Kliesch, Julien Merta, Hedwig E. Deubzer, Christian Bäumer, Feline Heinzelmann, Stefanie Schulze Schleithoff, Friederike Koerber, Angelika Eggert, Rudolf Schwarz, Thorsten Simon, Beate Timmermann
Publikováno v:
Current Oncology, Vol 29, Iss 11, Pp 8222-8234 (2022)
Background: Despite an intensive multimodal treatment approach, approximately 50% of high-risk (HR) neuroblastoma (NB) patients experience progression. Despite the advances in targeted therapy, high-dose chemotherapy, and other systemic treatment opt
Externí odkaz:
https://doaj.org/article/2eda78254f904a3a9f743eb2d70d7c1b
Autor:
Alina Meeser, Christoph Bartenhagen, Lisa Werr, Anna-Maria Hellmann, Yvonne Kahlert, Nadine Hemstedt, Peter Nürnberg, Janine Altmüller, Sandra Ackermann, Barbara Hero, Thorsten Simon, Martin Peifer, Matthias Fischer, Carolina Rosswog
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Background Telomere maintenance mechanisms (TMM) are a hallmark of high-risk neuroblastoma, and are conferred by activation of telomerase or alternative lengthening of telomeres (ALT). However, detection of TMM is not yet part of the clinica
Externí odkaz:
https://doaj.org/article/04d7590f1e6a4f35ba877b94d65b186b
Autor:
Stefania Sorrentino, Shifra Ash, Riccardo Haupt, Dominique Plantaz, Isabelle Schiff, Barbara Hero, Thorsten Simon, Denis Kachanov, Tatyana Shamanskaya, Katheljine Kraal, Annemieke Littooij, Alexsandra Wieczoreck, Walentyna Balwierz, Geneviève Laureys, Catherine Trager, Fiammetta Sertorio, Giovanni Erminio, Martina Fragola, Maja Beck Popovic, Bruno De Bernardi, Toby Trahair
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
IntroductionBetween 5 and 15% of children with neuroblastoma (NB) present with or develop spinal canal invasion (SCI). The majority of these children have symptoms of epidural compression of spinal cord and/or spinal nerves. Treatment of NB-SCI is co
Externí odkaz:
https://doaj.org/article/8a44d9405a7c4ce889fd9b3a565c092b
Autor:
Michaela Kuhlen, Christina Pamporaki, Marina Kunstreich, Stefan A. Wudy, Michaela F. Hartmann, Mirko Peitzsch, Christian Vokuhl, Guido Seitz, Michael C. Kreissl, Thorsten Simon, Barbara Hero, Michael C. Frühwald, Peter Vorwerk, Antje Redlich
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
In children and adolescents, neuroblastoma (NBL), pheochromocytoma (PCC), and adrenocortical tumors (ACT) can arise from the adrenal gland. It may be difficult to distinguish between these three entities including associated extra-adrenal tumors (par
Externí odkaz:
https://doaj.org/article/ac8972243d7a4ddfbb8232006990456e
Autor:
Sabine A. Hartlieb, Lina Sieverling, Michal Nadler-Holly, Matthias Ziehm, Umut H. Toprak, Carl Herrmann, Naveed Ishaque, Konstantin Okonechnikov, Moritz Gartlgruber, Young-Gyu Park, Elisa Maria Wecht, Larissa Savelyeva, Kai-Oliver Henrich, Carolina Rosswog, Matthias Fischer, Barbara Hero, David T. W. Jones, Elke Pfaff, Olaf Witt, Stefan M. Pfister, Richard Volckmann, Jan Koster, Katharina Kiesel, Karsten Rippe, Sabine Taschner-Mandl, Peter Ambros, Benedikt Brors, Matthias Selbach, Lars Feuerbach, Frank Westermann
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Alternative lengthening of telomeres (ALT) is associated with a poor outcome in neuroblastoma. Here, the authors find that ALT is associated with mutated ATRX and/or reduced protein abundance, frequent telomeric repeat loci and heterochromatic telome
Externí odkaz:
https://doaj.org/article/451b2c4a26e94327b98d615c78ab75da
Autor:
Luis Martí-Bonmatí, Ángel Alberich-Bayarri, Ruth Ladenstein, Ignacio Blanquer, J. Damian Segrelles, Leonor Cerdá-Alberich, Polyxeni Gkontra, Barbara Hero, J. M. García-Aznar, Daniel Keim, Wolfgang Jentner, Karine Seymour, Ana Jiménez-Pastor, Ismael González-Valverde, Blanca Martínez de las Heras, Samira Essiaf, Dawn Walker, Michel Rochette, Marian Bubak, Jordi Mestres, Marco Viceconti, Gracia Martí-Besa, Adela Cañete, Paul Richmond, Kenneth Y. Wertheim, Tomasz Gubala, Marek Kasztelnik, Jan Meizner, Piotr Nowakowski, Salvador Gilpérez, Amelia Suárez, Mario Aznar, Giuliana Restante, Emanuele Neri
Publikováno v:
European Radiology Experimental, Vol 4, Iss 1, Pp 1-11 (2020)
Abstract PRIMAGE is one of the largest and more ambitious research projects dealing with medical imaging, artificial intelligence and cancer treatment in children. It is a 4-year European Commission-financed project that has 16 European partners in t
Externí odkaz:
https://doaj.org/article/05e720491a5543918fb8093e96ef6ca4
Autor:
Oliver Zolk, Annika von dem Knesebeck, Norbert Graf, Thorsten Simon, Barbara Hero, Hashim Abdul-Khaliq, Mohamed Abd El Rahman, Claudia Spix, Benjamin Mayer, Susanne Elsner, Judith Gebauer, Thorsten Langer
Publikováno v:
JMIR Research Protocols, Vol 11, Iss 2, p e27898 (2022)
BackgroundIn childhood cancer survivors (survival of 5 years or more after diagnosis), cardiac toxicity is the most common nonmalignant cause of death attributed to treatment-related consequences. Identifying patients at risk of developing late cardi
Externí odkaz:
https://doaj.org/article/a6a5bceb52ee41719f45b64efa932c84
Autor:
Kiana Kreitz, Angela Ernst, René Schmidt, Thorsten Simon, Matthias Fischer, Ruth Volland, Barbara Hero, Frank Berthold
Publikováno v:
Cancer Medicine, Vol 8, Iss 17, Pp 7236-7243 (2019)
Abstract Background The prognosis of patients with recurrences from stage 4 neuroblastoma is not uniformly dismal. The evaluation of new therapies therefore needs to consider the individual risks of the treated patients. This study aims to define cli
Externí odkaz:
https://doaj.org/article/d309d4e510df4f1a8b8d464cc9dd9b5f