Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Barbara, Haenzi"'
Autor:
Bart Nieuwenhuis, Amanda C Barber, Rachel S Evans, Craig S Pearson, Joachim Fuchs, Amy R MacQueen, Susan van Erp, Barbara Haenzi, Lianne A Hulshof, Andrew Osborne, Raquel Conceicao, Tasneem Z Khatib, Sarita S Deshpande, Joshua Cave, Charles Ffrench‐Constant, Patrice D Smith, Klaus Okkenhaug, Britta J Eickholt, Keith R Martin, James W Fawcett, Richard Eva
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 8, Pp 1-24 (2020)
Abstract Peripheral nervous system (PNS) neurons support axon regeneration into adulthood, whereas central nervous system (CNS) neurons lose regenerative ability after development. To better understand this decline whilst aiming to improve regenerati
Externí odkaz:
https://doaj.org/article/774319b15576431a80d815b1901eaee3
Autor:
Emad Moeendarbary, Isabell P. Weber, Graham K. Sheridan, David E. Koser, Sara Soleman, Barbara Haenzi, Elizabeth J. Bradbury, James Fawcett, Kristian Franze
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Glial scars are thought to provide a biochemical and mechanical barrier to neuronal regeneration post-injury, but the mechanical properties of the scars have not been studied in detail. Here the authors perform atomic force microscopy measurements of
Externí odkaz:
https://doaj.org/article/f3d2bdc08870472282335918d0b3b16c
Autor:
Heleen M. Van’t Spijker, Dáire Rowlands, Jean Rossier, Barbara Haenzi, James W. Fawcett, Jessica C. F. Kwok
Publikováno v:
Neural Plasticity, Vol 2019 (2019)
The perineuronal net (PNN) is a mesh-like proteoglycan structure on the neuronal surface which is involved in regulating plasticity. The PNN regulates plasticity via multiple pathways, one of which is direct regulation of synapses through the control
Externí odkaz:
https://doaj.org/article/b6863ec9885c4fce8c835836a3d92d17
Autor:
Matthias B. Moor, Barbara Haenzi, Finola Legrand, Robert Koesters, Nancy E. Hynes, Olivier Bonny
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Ablation of the Mediator of ErbB2-driven Cell Motility 1 (Memo1) in mice altered calcium homeostasis and renal calcium transporter abundance by an unknown mechanism. Here, we investigated the role of intrarenal Memo in renal calcium handling. We have
Externí odkaz:
https://doaj.org/article/77139af41fe94aa58d899136b0a2998c
Autor:
Barbara Haenzi, Lawrence D. F. Moon
Publikováno v:
Neural Plasticity, Vol 2017 (2017)
Extensive research is ongoing that concentrates on finding therapies to enhance CNS regeneration after spinal cord injury (SCI) and to cure paralysis. This review sheds light on the role of the FGFR pathway in the injured spinal cord and discusses va
Externí odkaz:
https://doaj.org/article/d3eba14d49fc4d0e92e2b09e0c195668
Autor:
Alejandro Carnicer-Lombarte, James W. Fawcett, Bart Nieuwenhuis, Sam Hilton, Joost Verhaagen, Barbara Hobo, Barbara Haenzi
Publikováno v:
Gene Therapy
Gene Therapy, 28, 56-74. Nature Publishing Group
Gene Therapy, 28(1-2), 56-74. Nature Publishing Group
Nieuwenhuis, B, Haenzi, B, Hilton, S, Carnicer-Lombarte, A, Hobo, B, Verhaagen, J & Fawcett, J W 2021, ' Optimization of adeno-associated viral vector-mediated transduction of the corticospinal tract : comparison of four promoters ', Gene Therapy, vol. 28, no. 1-2, pp. 56-74 . https://doi.org/10.1038/s41434-020-0169-1
Gene Therapy, 28, 56-74. Nature Publishing Group
Gene Therapy, 28(1-2), 56-74. Nature Publishing Group
Nieuwenhuis, B, Haenzi, B, Hilton, S, Carnicer-Lombarte, A, Hobo, B, Verhaagen, J & Fawcett, J W 2021, ' Optimization of adeno-associated viral vector-mediated transduction of the corticospinal tract : comparison of four promoters ', Gene Therapy, vol. 28, no. 1-2, pp. 56-74 . https://doi.org/10.1038/s41434-020-0169-1
Funder: This research was funded by a Nathalie Rose Barr award (NRB110) from the International Spinal Research Trust, and support from Medical Research Council (MR/R004544/1 & MR/R004463/1), NWO (013-16-002), Czech Ministry of Education (CZ.02.1.01/0
Autor:
Barbara Haenzi, Katharina Gers-Barlag, Halima Akhoundzadeh, Thomas H Hutson, Sean C Menezes, Mary Bartlett Bunge, Lawrence D F Moon
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150541 (2016)
Spinal cord injury (SCI) is a severe condition that affects many people and results in high health care costs. Therefore, it is essential to find new targets for treatment. The fibroblast growth factor receptor 1 (FGFR1) signalling pathway has a hist
Externí odkaz:
https://doaj.org/article/2bb7c204f00449488962cbb93cc7e63b
Autor:
Barbara Haenzi, Olivier Bonny, Arjun Prakash Sridharan, Nancy E. Hynes, Matthias B. Moor, Suresh K. Ramakrishnan, Yao Zhu, Katalin Bartos, David Sheehan, Fanny Durussel, Sophie Braga-Lagache
Memo1deletion in mice causes premature aging and an unbalanced metabolism partially resemblingFgf23andKlotholoss-of-function animals. We report a role for Memo’s redox function in renal FGF23-Klotho signaling using mice with postnatally induced Mem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::608f9cc6710f18994fd8ddbcbf163415
https://doi.org/10.1101/2020.12.04.402511
https://doi.org/10.1101/2020.12.04.402511
Autor:
Charles ffrench-Constant, Craig S Pearson, Amanda C. Barber, Keith R Martin, Bart Nieuwenhuis, Tasneem Z Khatib, Patrice D. Smith, Rachel S Evans, Lianne A Hulshof, Joachim Fuchs, Richard Eva, Klaus Okkenhaug, Raquel D. Conceição, Sarita S Deshpande, Britta J. Eickholt, Andrew Osborne, Joshua Cave, James W. Fawcett, Barbara Haenzi, Susan van Erp, Amy R. MacQueen
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 8, Pp n/a-n/a (2020)
Nieuwenhuis, B, Barber, A C, Evans, R S, Pearson, C S, Fuchs, J, MacQueen, A R, van Erp, S, Haenzi, B, Hulshof, L A, Osborne, A, Conceicao, R, Khatib, T Z, Deshpande, S S, Cave, J, Ffrench-Constant, C, Smith, P D, Okkenhaug, K, Eickholt, B J, Martin, K R, Fawcett, J W & Eva, R 2020, ' PI 3-kinase delta enhances axonal PIP 3 to support axon regeneration in the adult CNS ', EMBO Molecular Medicine, vol. 12, no. 8, e11674 . https://doi.org/10.15252/emmm.201911674
EMBO Molecular Medicine, 12. Wiley-Blackwell
Nieuwenhuis, B, Barber, A C, Evans, R S, Pearson, C S, Fuchs, J, MacQueen, A R, van Erp, S, Haenzi, B, Hulshof, L A, Osborne, A, Conceicao, R, Khatib, T Z, Deshpande, S S, Cave, J, Ffrench-Constant, C, Smith, P D, Okkenhaug, K, Eickholt, B J, Martin, K R, Fawcett, J W & Eva, R 2020, ' PI 3-kinase delta enhances axonal PIP 3 to support axon regeneration in the adult CNS ', EMBO Molecular Medicine, vol. 12, no. 8, e11674 . https://doi.org/10.15252/emmm.201911674
EMBO Molecular Medicine, 12. Wiley-Blackwell
Peripheral nervous system (PNS) neurons support axon regeneration into adulthood, whereas central nervous system (CNS) neurons lose regenerative ability after development. To better understand this decline whilst aiming to improve regeneration, we fo
Autor:
Bart, Nieuwenhuis, Amanda C, Barber, Rachel S, Evans, Craig S, Pearson, Joachim, Fuchs, Amy R, MacQueen, Susan, van Erp, Barbara, Haenzi, Lianne A, Hulshof, Andrew, Osborne, Raquel, Conceicao, Tasneem Z, Khatib, Sarita S, Deshpande, Joshua, Cave, Charles, Ffrench-Constant, Patrice D, Smith, Klaus, Okkenhaug, Britta J, Eickholt, Keith R, Martin, James W, Fawcett, Richard, Eva
Publikováno v:
EMBO Molecular Medicine
Peripheral nervous system (PNS) neurons support axon regeneration into adulthood, whereas central nervous system (CNS) neurons lose regenerative ability after development. To better understand this decline whilst aiming to improve regeneration, we fo