Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Barbara, Franceschini"'
Autor:
Barbara Oliviero, Michele Dei Cas, Aida Zulueta, Roberta Maiello, Alessandro Villa, Carla Martinelli, Elena Del Favero, Monica Falleni, Linda Montavoci, Stefania Varchetta, Dalila Mele, Matteo Donadon, Cristiana Soldani, Barbara Franceschini, Marcello Maestri, Gaetano Piccolo, Matteo Barabino, Paolo Pietro Bianchi, Jesus M. Banales, Stefania Mantovani, Mario U. Mondelli, Anna Caretti
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Cholangiocarcinoma (CCA) is a rare cancer characterized by a global increasing incidence. Extracellular vesicles (EV) contribute to many of the hallmarks of cancer through transfer of their cargo molecules. The sphingolipid (SPL) profile of
Externí odkaz:
https://doaj.org/article/bb75d917f167424e9b8d30fa461784d6
Autor:
Michela Anna Polidoro, Erika Ferrari, Cristiana Soldani, Barbara Franceschini, Giuseppe Saladino, Arianna Rosina, Andrea Mainardi, Francesca D’Autilia, Nicola Pugliese, Guido Costa, Matteo Donadon, Guido Torzilli, Simona Marzorati, Marco Rasponi, Ana Lleo
Publikováno v:
JHEP Reports, Vol 6, Iss 1, Pp 100910- (2024)
Background & Aims: Cholangiocarcinoma (CCA) is a primary liver tumour characterised by a poor prognosis and limited therapeutic options. Available 3D human CCA models fail to faithfully recapitulate the tumour niche. We aimed to develop an innovative
Externí odkaz:
https://doaj.org/article/5e864ded3a464d3da96a59ddc776a7f3
Autor:
Giulia De Simone, Cristiana Soldani, Aurelia Morabito, Barbara Franceschini, Fabrizio Ferlan, Guido Costa, Roberta Pastorelli, Matteo Donadon, Laura Brunelli
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Tumor-associated macrophages (TAMs) represent one of the main tumor-infiltrating immune cell types and are generally categorized into either of two functionally contrasting subtypes, namely classical activated M1 macrophages and alternatively activat
Externí odkaz:
https://doaj.org/article/0b11e33e022146c394f7ebfb6ed1ddfa
Autor:
Aurora Gazzillo, Camilla Volponi, Cristiana Soldani, Michela Anna Polidoro, Barbara Franceschini, Ana Lleo, Eduardo Bonavita, Matteo Donadon
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 26 (2023)
Liver cancer represents the fourth leading cause of cancer-associated death worldwide. The heterogeneity of its tumor microenvironment (TME) is a major contributing factor of metastasis, relapse, and drug resistance. Regrettably, late diagnosis makes
Externí odkaz:
https://doaj.org/article/96048340d86a4c5f9e56cebe65104a6f
Autor:
Barbara Oliviero, Stefania Varchetta, Dalila Mele, Greta Pessino, Roberta Maiello, Monica Falleni, Delfina Tosi, Matteo Donadon, Cristiana Soldani, Barbara Franceschini, Guido Torzilli, Gaetano Piccolo, Matteo Barabino, Enrico Opocher, Marcello Maestri, Stefano Bernuzzi, Kai W. Wucherpfennig, Mario U. Mondelli, Stefania Mantovani
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
The major histocompatibility complex-class I chain related proteins A and B (MICA/B) is upregulated because of cellular stress and MICA/B shedding by cancer cells causes escape from NKG2D recognition favoring the emergence of cancers. Cholangiocarcin
Externí odkaz:
https://doaj.org/article/5aa25f350bde4679a9569a19f98cfd67
Autor:
Alberto Mantovani, Barbara Franceschini, Domenico Mavilio, Cecilia Garlanda, Elena Bruni, Matteo Maria Cimino, Matteo Donadon, Roberta Carriero, Sara Terzoli, Rocco Piazza, Sarina Ravens, Immo Prinz, Valentina Cazzetta, Paolo Marzano, Paolo Kunderfranco, Clelia Peano, Cristiana Soldani, Federico Simone Colombo, Guido Torzilli, Joanna Mikulak
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 7 (2022)
Background More than 50% of all patients with colorectal cancer (CRC) develop liver metastases (CLM), a clinical condition characterized by poor prognosis and lack of reliable prognostic markers. Vδ1 cells are a subset of tissue-resident gamma delta
Externí odkaz:
https://doaj.org/article/3aa6fb67f4ac490493471708b65d99fc
Autor:
Guido Costa, Carlo Sposito, Cristiana Soldani, Michela A. Polidoro, Barbara Franceschini, Federica Marchesi, Faizan D. Nasir, Matteo Virdis, Andrea Vingiani, Ana Leo, Luca Di Tommaso, Soumya Kotha, Alberto Mantovani, Vincenzo Mazzaferro, Matteo Donadon, Guido Torzilli
Publikováno v:
International Journal of Surgery. 109:1311-1317
Autor:
Silvia Giordano, Angela Marika Siciliano, Matteo Donadon, Cristiana Soldani, Barbara Franceschini, Ana Lleo, Luca Di Tommaso, Matteo Cimino, Guido Torzilli, Hidekazu Saiki, Hiroki Nakajima, Sen Takeda, Enrico Davoli
Publikováno v:
Applied Sciences, Vol 12, Iss 9, p 4244 (2022)
Currently used techniques for intraoperative assessment of tumor resection margins are time-consuming and laborious and, more importantly, lack specificity. Moreover, pathological diagnosis during surgery does not often give a clear outcome. Recent a
Externí odkaz:
https://doaj.org/article/07451e8885144565830d82948c3bc860
Autor:
Nina Cortese, Roberta Carriero, Marialuisa Barbagallo, Anna Rita Putignano, Guido Costa, Fabio Giavazzi, Fabio Grizzi, Fabio Pasqualini, Clelia Peano, Gianluca Basso, Sergio Marchini, Federico Simone Colombo, Cristiana Soldani, Barbara Franceschini, Luca Di Tommaso, Luigi Terracciano, Matteo Donadon, Guido Torzilli, Paolo Kunderfranco, Alberto Mantovani, Federica Marchesi
Publikováno v:
Cancer Immunology Research. 11:405-420
Patients with colorectal liver metastasis (CLM) present with heterogenous clinical outcomes and improved classification is needed to ameliorate the therapeutic output. Macrophages (Mϕ) hold promise as prognostic classifiers and therapeutic targets.
Autor:
Giorgia Alvisi, Alberto Termanini, Cristiana Soldani, Federica Portale, Roberta Carriero, Karolina Pilipow, Guido Costa, Michela Polidoro, Barbara Franceschini, Ines Malenica, Simone Puccio, Veronica Lise, Giovanni Galletti, Veronica Zanon, Federico Simone Colombo, Gabriele De Simone, Michele Tufano, Alessio Aghemo, Luca Di Tommaso, Clelia Peano, Javier Cibella, Matteo Iannacone, Rahul Roychoudhuri, Teresa Manzo, Matteo Donadon, Guido Torzilli, Paolo Kunderfranco, Diletta Di Mitri, Enrico Lugli, Ana Lleo
Publikováno v:
Journal of Hepatology. 77:1359-1372
The landscape and function of the immune infiltrate of intrahepatic cholangiocarcinoma (iCCA), a rare, yet aggressive tumor of the biliary tract, remains poorly characterized, limiting development of successful immunotherapies. Herein, we aimed to de