Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Barbara, Chruścicka"'
Autor:
Stanisław Malicki, Anna Czarna, Edyta Żyła, Barbara Pucelik, Wojciech Gałan, Barbara Chruścicka, Marta Kamińska, Alicja Sochaj-Gregorczyk, Katarzyna Magiera-Mularz, Jun Wang, Marek Winiarski, Małgorzata Benedyk-Machaczka, Joanna Kozieł, Grzegorz Dubin, Piotr Mydel
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Programmed death receptor 1, PD1, modulates the function of immune cells by providing inhibitory signals and constitutes the marker of immune exhaustion. Monitoring the level of PD1 promises a useful diagnostic approach in autoimmune disease
Externí odkaz:
https://doaj.org/article/143eec6f6a53493c9969dd0d95345919
Screening and characterization of aptamers recognizing the periodontal pathogen Tannerella forsythia
Publikováno v:
FEBS Open Bio, Vol 14, Iss 3, Pp 498-504 (2024)
Periodontal disease is one of the most common forms of inflammation. It is currently diagnosed by observing symptoms such as gingival bleeding and attachment loss. However, the detection of biomarkers that precede such symptoms would allow earlier di
Externí odkaz:
https://doaj.org/article/f8fb4746b1354bbe959f23ad72984b76
Autor:
Anna Stankiewicz, Katarzyna Kaczorowska, Ryszard Bugno, Aneta Kozioł, Maria H. Paluchowska, Grzegorz Burnat, Barbara Chruścicka, Paulina Chorobik, Piotr Brański, Joanna M. Wierońska, Beata Duszyńska, Andrzej Pilc, Andrzej J. Bojarski
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 211-225 (2022)
Considering the allosteric regulation of mGlu receptors for potential therapeutic applications, we developed a group of 1,2,4-oxadiazole derivatives that displayed mGlu4 receptor positive allosteric modulatory activity (EC50 = 282–656 nM). Selectiv
Externí odkaz:
https://doaj.org/article/986c7044b75f497b83b535e2846fde7c
Autor:
Dasiel O. Borroto-Escuela, Cristina Cuesta-Marti, Alexander Lopez-Salas, Barbara Chruścicka-Smaga, Minerva Crespo-Ramírez, Emiliano Tesoro-Cruz, Daniel A. Palacios-Lagunas, Miguel Perez de la Mora, Harriët Schellekens, Kjell Fuxe
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
In the last 10 years, it has become increasingly clear that large numbers of axon collaterals extend from the oxytocin (OXT) hypothalamic axons, especially the parvocellular components, to other brain regions. Consequently, the OXT signaling system f
Externí odkaz:
https://doaj.org/article/38092d95f470495597d9ecd9c76ca75e
Autor:
Stanisław Malicki, Barbara Pucelik, Edyta Żyła, Małgorzata Benedyk-Machaczka, Wojciech Gałan, Anna Golda, Alicja Sochaj-Gregorczyk, Marta Kamińska, João Crispim Encarnação, Barbara Chruścicka, Hans-Peter Marti, Tony Jialiang Chen, Katarzyna Magiera-Mularz, Bartosz Zięba, Tad A. Holak, Janusz M. Dąbrowski, Anna Czarna, Joanna Kozieł, Piotr Mydel, Grzegorz Dubin
Publikováno v:
Pharmaceuticals, Vol 15, Iss 6, p 697 (2022)
Immune checkpoint targeting immunotherapy has revolutionized the treatment of certain cancers in the recent years. Determination of the status of immune checkpoint expression in particular cancers may assist decision making. Here, we describe the dev
Externí odkaz:
https://doaj.org/article/00bcb478d3854a93a3bfa85fb6e7fcde
Autor:
Paromita Sen, Eoin Sherwin, Kiran Sandhu, Thomaz F.S. Bastiaanssen, Gerard M. Moloney, Anna Golubeva, Patrick Fitzgerald, Ana Paula Ventura Da Silva, Barbara Chruścicka-Smaga, Loreto Olavarría-Ramírez, Clementine Druelle, David Campos, Pooja Jayaprakash, Kieran Rea, Ian B. Jeffery, Helene Savignac, Sasha Chetal, Imke Mulder, Harriet Schellekens, Timothy G. Dinan, John F. Cryan
Publikováno v:
Brain, Behavior, and Immunity. 106:115-126
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterised by deficits in social behaviour, increased repetitive behaviour, anxiety and gastrointestinal symptoms. The aetiology of ASD is complex and involves an interplay of genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::746f2eb020a35693169b27a21d2a5556
https://doi.org/10.1016/j.bbi.2022.08.007
https://doi.org/10.1016/j.bbi.2022.08.007
Autor:
Piotr Brański, Magdalena Kolasa, Marta Dziedzicka-Wasylewska, Grzegorz Burnat, Barbara Chruścicka, Andrzej Pilc, Joanna Solich
Publikováno v:
Pharmacological Reports. 72:1358-1369
Background The serotonin 5-HT1A receptor (5-HT1AR) and metabotropic glutamate receptor 4 (mGlu4) have been implicated as sites of antipsychotic drug action. 5-HT1AR belongs to the A class of G protein-coupled receptors (GPCRs); mGlu4 is a representat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cf779c797c746fe455bcaee5ee37e8b
https://doi.org/10.1007/s43440-020-00114-1
https://doi.org/10.1007/s43440-020-00114-1
Autor:
Veronika Binder, Barbara Chruścicka-Smaga, Brith Bergum, Stéphane Jaisson, Philippe Gillery, Joar Sivertsen, Tor Hervig, Marta Kaminska, Ronak Tilvawala, Venkatesh V. Nemmara, Paul R. Thompson, Jan Potempa, Hans-Peter Marti, Piotr Mydel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a74cc35a67b1c6543ebbdb020a36c6da
https://ruj.uj.edu.pl/xmlui/handle/item/305050
https://ruj.uj.edu.pl/xmlui/handle/item/305050
Autor:
Anna, Stankiewicz, Katarzyna, Kaczorowska, Ryszard, Bugno, Aneta, Kozioł, Maria H, Paluchowska, Grzegorz, Burnat, Barbara, Chruścicka, Paulina, Chorobik, Piotr, Brański, Joanna M, Wierońska, Beata, Duszyńska, Andrzej, Pilc, Andrzej J, Bojarski
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Considering the allosteric regulation of mGlu receptors for potential therapeutic applications, we developed a group of 1,2,4-oxadiazole derivatives that displayed mGlu4 receptor positive allosteric modulatory activity (EC50 = 282–656 nM). Selectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::027706e7f575b861917c4d10a420e894
https://pubmed.ncbi.nlm.nih.gov/34894953
https://pubmed.ncbi.nlm.nih.gov/34894953
Autor:
Miguel Pérez de la Mora, Harriët Schellekens, Kjell Fuxe, Dasiel O. Borroto-Escuela, Juan C. Hernández-Mondragón, Patrizia Ambrogini, Minerva Crespo-Ramírez, Maria Lindskog, Barbara Chruścicka
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1927, p 1927 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Serotonin communication operates mainly in the extracellular space and cerebrospinal fluid (CSF), using volume transmission with serotonin moving from source to target cells (neurons and astroglia) via energy gradients, leading to the diffusion and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::309027f97cc08b568811a970e4ff9a8d
https://www.mdpi.com/1422-0067/22/4/1927
https://www.mdpi.com/1422-0067/22/4/1927