Ligation Motifs in Zinc-Bound Sulfonamide Drugs Assayed by IR Ion Spectroscopy

Autor: Davide Corinti, Barbara Chiavarino, Philippe Maitre, Maria Elisa Crestoni, Simonetta Fornarini

Publikováno v: Molecules, Vol 27, Iss 10, p 3144 (2022)

The sulfonamide–zinc ion interaction, performing a key role in various biological contexts, is the focus of the present study, with the aim of elucidating ligation motifs in zinc complexes of sulfa drugs, namely sulfadiazine (SDZ) and sulfathiazole

Externí odkaz: https://doaj.org/article/6d7a45b8566a40d38bbb0195648ee30f

Elusive intermediates in cisplatin reaction with target amino acids: Platinum(II)-cysteine complexes assayed by IR ion spectroscopy and DFT calculations

Autor: Davide Corinti, Roberto Paciotti, Cecilia Coletti, Nazzareno Re, Barbara Chiavarino, Maria Elisa Crestoni, Simonetta Fornarini

Publikováno v: Journal of inorganic biochemistry. 237

The reactivity of a widely used metal based antineoplastic drug, cisplatin, cis-PtCl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c356295b133fd900e77c8cb4fb49fb1c
https://pubmed.ncbi.nlm.nih.gov/36209532

Corrigendum: Can an Elusive Platinum(III) Oxidation State be Exposed in an Isolated Complex?

Autor: Davide Corinti, Gilles Frison, Barbara Chiavarino, Elisabetta Gabano, Domenico Osella, Maria Elisa Crestoni, Simonetta Fornarini

Publikováno v: Angewandte Chemie International Edition. 61

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::55efdc8077a8392c8b7fefa27331cce6
https://doi.org/10.1002/anie.202202822

Short-lived intermediates (encounter complexes) in cisplatin ligand exchange elucidated by infrared ion spectroscopy

Autor: Roberto Paciotti, Nazzareno Re, Maria Elisa Crestoni, Simonetta Fornarini, Davide Corinti, Philippe Maître, Barbara Chiavarino, Cecilia Coletti

Publikováno v: International Journal of Mass Spectrometry
International Journal of Mass Spectrometry, Elsevier, 2019, 435, pp.7-17. ⟨10.1016/j.ijms.2018.10.012⟩

Cisplatin (cis-diamminedichloroplatinum(II), cis-[PtCl2(NH3)2]), widely used drug in cancer treatment, has been allowed to react with simple molecular targets (L) mimicking biological functional groups. The selected molecules (L = acetamide, dimethyl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78c8e208152b31dfe8c4d052a6363fed
https://doi.org/10.1016/j.ijms.2018.10.012

Molecular Basis for the Remarkably Different Gas-Phase Behavior of Deprotonated Thyroid Hormones Triiodothyronine (T3) and Reverse Triiodothyronine (rT3): A Clue for Their Discrimination?

Autor: Davide Corinti, Mattia Spano, Aura Tintaru, Maria Elisa Crestoni, Simonetta Fornarini, Barbara Chiavarino

Publikováno v: Analytical Chemistry

Thyroid hormones are biologically active small molecules responsible for growth and development regulation, basal metabolic rate, and lipid and carbohydrate metabolism. Liquid chromatography mass spectrometry (LC–MS) can be used to quantify thyroid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e6ae680983083e058d163e72dd32477
http://hdl.handle.net/11573/1624532