Zobrazeno 1 - 10 of 130 pro vyhledávání: '"Barbara, Cacciari"'
1
Akademický článek
Synthesis and Biological Evaluation of Highly Active 7-Anilino Triazolopyrimidines as Potent Antimicrotubule Agents
Autor: Paola Oliva, Romeo Romagnoli, Barbara Cacciari, Stefano Manfredini, Chiara Padroni, Andrea Brancale, Salvatore Ferla, Ernest Hamel, Diana Corallo, Sanja Aveic, Noemi Milan, Elena Mariotto, Giampietro Viola, Roberta Bortolozzi
Publikováno v: Pharmaceutics, Vol 14, Iss 6, p 1191 (2022)
Two different series of fifty-two compounds, based on 3′,4′,5′-trimethoxyaniline (7a–ad) and variably substituted anilines (8a–v) at the 7-position of the 2-substituted-[1,2,4]triazolo [1,5-a]pyrimidine nucleus, had moderate to potent antip
Externí odkaz: https://doaj.org/article/d51587f8f4754b5eb51cf08ab0edb9d3
Zobrazit plný text záznamu
2
Akademický článek
Schematic overview of oligosaccharides, with survey on their major physiological effects and a focus on milk ones
Autor: Stefania Hanau, Shawgi Hago Almugadam, Eugenia Sapienza, Barbara Cacciari, Maria Cristina Manfrinato, Alessandro Trentini, John Frederick Kennedy
Publikováno v: Carbohydrate Polymer Technologies and Applications, Vol 1, Iss , Pp 100013- (2020)
While Biochemistry textbooks for University degree courses do not deal with oligosaccharides, this subject is now becoming essential in Biomedical Sciences for several reasons. Oligosaccharides are currently used in foods and beverages for their usef
Externí odkaz: https://doaj.org/article/e40b6e4df9e24801a454d1d1b2fe9049
Zobrazit plný text záznamu
3
Akademický článek
Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3′,4′,5′-trimethoxyphenyl)-3-(2′-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach
Autor: Delia Preti, Romeo Romagnoli, Riccardo Rondanin, Barbara Cacciari, Ernest Hamel, Jan Balzarini, Sandra Liekens, Dominique Schols, Francisco Estévez-Sarmiento, José Quintana, Francisco Estévez
Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 1225-1238 (2018)
Inhibition of microtubule function using tubulin targeting agents has received growing attention in the last several decades. The indole scaffold has been recognized as an important scaffold in the design of novel compounds acting as antimitotic agen
Externí odkaz: https://doaj.org/article/cb4e0939e984439cbabe4095ac2612e4
Zobrazit plný text záznamu
4
Akademický článek
Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3′,4′,5′-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold
Autor: Romeo Romagnoli, Filippo Prencipe, Paola Oliva, Barbara Cacciari, Jan Balzarini, Sandra Liekens, Ernest Hamel, Andrea Brancale, Salvatore Ferla, Stefano Manfredini, Matteo Zurlo, Alessia Finotti, Roberto Gambari
Publikováno v: Molecules, Vol 25, Iss 7, p 1690 (2020)
Two novel series of compounds based on the 4,5,6,7-tetrahydrothieno[2,3-c]pyridine and 4,5,6,7-tetrahydrobenzo[b]thiophene molecular skeleton, characterized by the presence of a 3′,4′,5′-trimethoxyanilino moiety and a cyano or an alkoxycarbonyl
Externí odkaz: https://doaj.org/article/8946c93be8954dfcb67f6f58d53d6edd
Zobrazit plný text záznamu
5
Thio-substituted derivatives of 4-amino-pyrazolo[3,4-d]pyrimidine-6-thiol as antiproliferative agents
Autor: Arianna Romani, Romeo Romagnoli, Barbara Cacciari, Stefania Hanau, Alessandro Trentini
Publikováno v: Future Medicinal Chemistry. 13:1515-1530
The current study was designed to identify new compounds as potential antiproliferative drug candidates. Synthesis of heteroaromatic bicyclic and monocyclic derivatives as purine bioisosters was employed. Their antiproliferative activity was studied
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4399f1039c7fabf72bd3b0bf060726b
https://doi.org/10.4155/fmc-2021-0131
Zobrazit plný text záznamu
6
Akademický článek
The Influence of the 1-(3-Trifluoromethyl-Benzyl)-1H-Pyrazole-4-yl Moiety on the Adenosine Receptors Affinity Profile of Pyrazolo[4,3-e][1,2,4]Triazolo[1,5-c]Pyrimidine Derivatives.
Autor: Stephanie Federico, Sara Redenti, Mattia Sturlese, Antonella Ciancetta, Sonja Kachler, Karl-Norbert Klotz, Barbara Cacciari, Stefano Moro, Giampiero Spalluto
Publikováno v: PLoS ONE, Vol 10, Iss 12, p e0143504 (2015)
A new series of pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine (PTP) derivatives has been developed in order to explore their affinity and selectivity profile at the four adenosine receptor subtypes. In particular, the PTP scaffold was conjugated at
Externí odkaz: https://doaj.org/article/7a562794d0ea427cae270d66fea9e79c
Zobrazit plný text záznamu
8
Schematic overview of oligosaccharides, with survey on their major physiological effects and a focus on milk ones
Autor: Barbara Cacciari, Maria Cristina Manfrinato, Eugenia Sapienza, Shawgi Hago Almugadam, Stefania Hanau, John Frederick Kennedy, Alessandro Trentini
Publikováno v: Carbohydrate Polymer Technologies and Applications, Vol 1, Iss, Pp 100013-(2020)
While Biochemistry textbooks for University degree courses do not deal with oligosaccharides, this subject is now becoming essential in Biomedical Sciences for several reasons. Oligosaccharides are currently used in foods and beverages for their usef
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6102782281f027deeac00a33fac27de7
http://hdl.handle.net/11392/2426991
Zobrazit plný text záznamu
9
8-(2-Furyl)adenine derivatives as A2A adenosine receptor ligands
Autor: Catia Lambertucci, Diego Dal Ben, Giampiero Spalluto, Michela Buccioni, Karl-Norbert Klotz, Ajiroghene Thomas, Stephanie Federico, Rosaria Volpini, Barbara Cacciari
Publikováno v: European Journal of Medicinal Chemistry. 70:525-535
Selective adenosine receptor modulators are potential tools for numerous therapeutic applications, including cardiovascular, inflammatory, and neurodegenerative diseases. In this work, the synthesis and biological evaluation at the four human adenosi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58db3093cab76b4134db808ca35b7076
https://doi.org/10.1016/j.ejmech.2013.10.006
Zobrazit plný text záznamu
10
A2Aadenosine receptor antagonists as therapeutic candidates: Are they still an interesting challenge?
Autor: Barbara Cacciari, Stephanie Federico, Giampiero Spalluto
In the past decades, many efforts were undertaken to develop ligands for the adenosine receptors, with the purpose to individuate agonists and antagonists affinity and selectivity for each subtypes, namely A1, A2A, A2B, and A3. These intense studies
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caea11a137a342ba1faf6caffd861a23
http://hdl.handle.net/11392/2396576
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje