Effects of Sorafenib, a Tyrosin Kinase Inhibitor, on Adrenocortical Cancer

Autor: Lidia Cerquetti, Barbara Bucci, Salvatore Raffa, Donatella Amendola, Roberta Maggio, Pina Lardo, Elisa Petrangeli, Maria Rosaria Torrisi, Vincenzo Toscano, Giuseppe Pugliese, Antonio Stigliano

Publikováno v: Frontiers in Endocrinology, Vol 12 (2021)

The lack of an effective medical treatment for adrenocortical carcinoma (ACC) has prompted the search for better treatment protocols for ACC neoplasms. Sorafenib, a tyrosine kinase inhibitor has exhibited effectiveness in the treatment of different h

Externí odkaz: https://doaj.org/article/46f8e3e0c533403d98c7547dcf7359a5

Effects of sorafenib, a tyrosin kinase inhibitor, on adrenocortical cancer cell line

Autor: Roberta Maggio, Vincenzo Toscano, Salvatore Raffa, Pina Lardo, Elisa Petrangeli, Antonio Stigliano, Chiara Simonini, Lidia Cerquetti, Giuseppe Pugliese, Barbara Bucci

Publikováno v: Endocrine Abstracts.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fb6a1ba35cd63c3f7f935d9e45e04330
https://doi.org/10.1530/endoabs.73.aep28

Role of Lamin A/C as Candidate Biomarker of Aggressiveness and Tumorigenicity in Glioblastoma Multiforme

Autor: Loredana Guglielmi, Raffaele Saporito, Chiara Di Pietro, Carla Musa, Fabrizio Bonaventura, Giuliana Gatti, Ferdinando Scavizzi, Igea D'Agnano, Francesca De Santa, Alessio Torcinaro, Marcello Raspa, Barbara Bucci, Ivan Arisi, Laura Vilardo

Publikováno v: Biomedicines 9 (2021). doi:10.3390/ biomedicines9101343
info:cnr-pdr/source/autori:Giuliana Gatti 1,+, Laura Vilardo 2,+, Carla Musa 2,+, Chiara Di Pietro 3, Fabrizio Bonaventura 3, Ferdinando Scavizzi 3, Alessio Torcinaro 3, Barbara Bucci 4, Raffaele Saporito 4, Ivan Arisi 5, Francesca De Santa 3, Marcello Raspa 3, Loredana Guglielmi 2, * and Igea D'Agnano 2,*/titolo:Role of Lamin A%2FC as Candidate Biomarker of Aggressiveness and Tumorigenicity in Glioblastoma Multiforme/doi:10.3390%2F biomedicines9101343/rivista:Biomedicines/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:9
Biomedicines, Vol 9, Iss 1343, p 1343 (2021)
Biomedicines
Volume 9
Issue 10

Nuclear lamina components have long been regarded as scaffolding proteins, forming a dense fibrillar structure necessary for the maintenance of the nucleus shape in all the animal kingdom. More recently, mutations, aberrant localisation and deregulat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7065e93162dccb7d02ae95a2b31d5f5e
https://publications.cnr.it/doc/457088

Antineoplastic Effect of a Combined Mitotane Treatment/Ionizing Radiation in Adrenocortical Carcinoma: A Preclinical Study

Autor: Barbara Bucci, Lidia Cerquetti, Giulia Carpinelli, Antonella Proietti, Vincenzo Toscano, Elisa Petrangeli, Guido Rindi, Pina Lardo, Antonio Stigliano, Raffaele Saporito

Publikováno v: Cancers
Volume 11
Issue 11
Cancers, Vol 11, Iss 11, p 1768 (2019)

Mitotane (MTT) is an adrenolytic drug used in adjuvant and advanced treatments of adrenocortical carcinoma (ACC). Ionizing radiation (IR) is also used in adrenal cancer treatment, even though its biological action remains unknown. To provide a reliab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::763c11230004bed90de7645d78600702

Differentiation of Caco-2 cells requires both transcriptional and post-translational down-regulation of Myc

Autor: Barbara Bucci, Armando Felsani, Igea D'Agnano, Marta Nardella, F. Zucco, Bruno D. Leoni, Manuela Natoli

Publikováno v: Differentiation (Lond.) 83 (2012): 116–127. doi:10.1016/j.diff.2011.10.005
info:cnr-pdr/source/autori:Leoni Bruno Daniele a; Natoli Manuela a; Nardella Marta a; Bucci Barbara c; Zucco Flavia a; D'Agnano Igea a,b; Felsani Armando a,b/titolo:Differentiation of Caco-2 cells requires both transcriptional and post-translational down-regulation of Myc/doi:10.1016%2Fj.diff.2011.10.005/rivista:Differentiation (Lond.)/anno:2012/pagina_da:116/pagina_a:127/intervallo_pagine:116–127/volume:83

Caco-2 cancer cell line is widely used to reproduce in vitro the differentiation of absorptive enterocytes of human intestinal epithelium. This cell line, when cultured over confluence for 21 days, spontaneously undergoes cell cycle arrest and differ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f605598063f50483ffc4abd3fa3793d4
https://doi.org/10.1016/j.diff.2011.10.005