Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Barb Stauffer"'
Autor:
Jeffrey Curtis Kern, Ronald L. Magolda, Shoichi Fukyama, Girija Krishnamurthy, Eugene John Trybulski, Barb Stauffer, William Jay Moore, Peter V.N. Bodine, Keith Pitts, Ramesh A. Bhat
Publikováno v:
Bioorganicmedicinal chemistry. 18(1)
Piperidinyl diphenylsulfonyl sulfonamides are a novel class of molecules that have inhibitory binding affinity for sFRP-1. As a secreted protein sFRP-1 inhibits the function of the secreted Wnt glycoprotein. Therefore, as inhibitors of sFRP-1 these s
Autor:
Jeffrey Curtis Kern, Peter V.N. Bodine, Shoichi Fukayama, Gregory S. Welmaker, Girija Krishnamurthy, Thomas Joseph Commons, Lisa Nogle, William Jay Moore, Ramesh A. Bhat, Keith Pitts, Eugene John Trybulski, Barb Stauffer, Wilson Matthew Allan, Igor Goljer, Ronald L. Magolda
Publikováno v:
Journal of medicinal chemistry. 52(1)
The diphenylsulfonyl sulfonamide scaffold represented by 1 (WAY-316606) are small molecule inhibitors of the secreted protein sFRP-1, an endogenous antagonist of the secreted glycoprotein Wnt. Modulators of the Wnt pathway have been proposed as anabo
Autor:
William J. Moore, Jeffrey C. Kern, Ramesh Bhat, Thomas J. Commons, Shoichi Fukayama, Igor Goljer, Girija Krishnamurthy, Ronald L. Magolda, Lisa Nogle, Keith Pitts, Barb Stauffer, Eugene J. Trybulski, Gregory S. Welmaker, Matthew Wilson, Peter V. N. Bodine
Publikováno v:
Journal of Medicinal Chemistry; Jan2009, Vol. 52 Issue 1, p105-116, 12p