Zobrazeno 1 - 10
of 284
pro vyhledávání: '"Baratchian M"'
Autor:
Bagneris, Claire, Senthil Kumar, Swathi, Baratchian, M., Britt, H., Tufa, A., Thalassinos, Kostas, Collins, M., Barrett, Tracey
Constitutive activation of the canonical NF-B signaling pathway is a major factor in Kaposi’s Sarcoma Herpes virus (KSHV) pathogenesis where it is essential for the survival of primary effusion lymphoma (PEL). Central to this process is persistent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::075865ce8d032a7592b189b06c0f5aa0
https://eprints.bbk.ac.uk/id/eprint/48201/1/PIIS0021925822004525.pdf
https://eprints.bbk.ac.uk/id/eprint/48201/1/PIIS0021925822004525.pdf
Autor:
Bagnéris C; Department of Biological Sciences, Institute of Structural Molecular Biology, Birkbeck College, London, UK., Senthil Kumar SL; Department of Biological Sciences, Institute of Structural Molecular Biology, Birkbeck College, London, UK., Baratchian M; Genitourinary Malignancies Research Center, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA., Britt HM; Division of Biosciences, Institute of Structural and Molecular Biology, University College London, London, UK., Assafa TE; Chemistry and Biochemistry Department, University of California Santa Cruz, Santa Cruz, California, USA., Thalassinos K; Department of Biological Sciences, Institute of Structural Molecular Biology, Birkbeck College, London, UK; Division of Biosciences, Institute of Structural and Molecular Biology, University College London, London, UK., Collins MK; Okinawa Institute of Science and Technology, Graduate University, Onna-son, Okinawa, Japan., Barrett TE; Department of Biological Sciences, Institute of Structural Molecular Biology, Birkbeck College, London, UK. Electronic address: t.barrett@bbk.ac.uk.
Publikováno v:
The Journal of biological chemistry [J Biol Chem] 2022 Jun; Vol. 298 (6), pp. 102012. Date of Electronic Publication: 2022 May 05.
Autor:
Baratchian M; Genitourinary Malignancies Research Center, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195., Tiwari R; Genitourinary Malignancies Research Center, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195., Khalighi S; Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH 44106., Chakravarthy A; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2M9, Canada., Yuan W; Division of Clinical Studies, The Institute of Cancer Research and Royal Marsden Hospital, London SM2 5NG, United Kingdom., Berk M; Genitourinary Malignancies Research Center, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195., Li J; Genitourinary Malignancies Research Center, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195., Guerinot A; Genitourinary Malignancies Research Center, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195., de Bono J; Division of Clinical Studies, The Institute of Cancer Research and Royal Marsden Hospital, London SM2 5NG, United Kingdom., Makarov V; Center for Immunotherapy and Precision Immuno-Oncology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195., Chan TA; Center for Immunotherapy and Precision Immuno-Oncology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195., Silverman RH; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195., Stark GR; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195., Varadan V; Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH 44106., De Carvalho DD; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2M9, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada., Chakraborty AA; Genitourinary Malignancies Research Center, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195., Sharifi N; Genitourinary Malignancies Research Center, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195.; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195.; Department of Hematology and Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH 44195.; Department of Urology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH 44125.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 May 24; Vol. 119 (21), pp. e2114324119. Date of Electronic Publication: 2022 May 18.
Autor:
Briggs, L.C., Chan, A.W.E., Davis, C.A., Whitelock, N., Hotiana, H., Baratchian, M., Bagneris, Claire, Selwood, D., Collins, M.K., Barrett, Tracey
Primary effusion lymphoma (PEL) is a lymphogenic disorder associated with KSHV infection. Key to the survival and proliferation of PEL is the canonical NF-kB pathway that becomes constitutively activated following overexpression of the viral oncoprot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::f6cbc5793b9a9edbbe23ae8c50bb6c1b
https://eprints.bbk.ac.uk/id/eprint/19849/6/19849A.pdf
https://eprints.bbk.ac.uk/id/eprint/19849/6/19849A.pdf
Autor:
Baratchian M; Genitourinary Malignancies Research Center, Lerner Research Institute, Cleveland Clinic, Cleveland, USA., McManus JM; Genitourinary Malignancies Research Center, Lerner Research Institute, Cleveland Clinic, Cleveland, USA., Berk MP; Genitourinary Malignancies Research Center, Lerner Research Institute, Cleveland Clinic, Cleveland, USA., Nakamura F; Genitourinary Malignancies Research Center, Lerner Research Institute, Cleveland Clinic, Cleveland, USA., Mukhopadhyay S; Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, USA., Xu W; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, USA., Erzurum S; Respiratory Institute, Cleveland Clinic, Cleveland, USA.; Lerner Research Institute, Cleveland Clinic, Cleveland, USA., Drazba J; Imaging Core, Lerner Research Institute, Cleveland Clinic, Cleveland, USA., Peterson J; Imaging Core, Lerner Research Institute, Cleveland Clinic, Cleveland, USA., Klein EA; Department of Urology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, USA., Gaston B; Herman Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, USA., Sharifi N; Genitourinary Malignancies Research Center, Lerner Research Institute, Cleveland Clinic, Cleveland, USA. sharifn@ccf.org.; Department of Urology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, USA. sharifn@ccf.org.; Department of Hematology and Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, USA. sharifn@ccf.org.
Publikováno v:
Scientific reports [Sci Rep] 2021 May 27; Vol. 11 (1), pp. 11130. Date of Electronic Publication: 2021 May 27.
Autor:
Li J; Genitourinary Malignancies Research Center, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA., Berk M; Genitourinary Malignancies Research Center, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA., Alyamani M; Genitourinary Malignancies Research Center, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA., Sabharwal N; Genitourinary Malignancies Research Center, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA., Goins C; Center for Therapeutics Discovery, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA., Alvarado J; Center for Therapeutics Discovery, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA., Baratchian M; Genitourinary Malignancies Research Center, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA., Zhu Z; Genitourinary Malignancies Research Center, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA., Stauffer S; Center for Therapeutics Discovery, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA., Klein EA; Genitourinary Malignancies Research Center, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.; Department of Urology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH 44195, USA., Sharifi N; Genitourinary Malignancies Research Center, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA. sharifn@ccf.org.; Department of Urology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH 44195, USA.; Department of Hematology and Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
Publikováno v:
Science translational medicine [Sci Transl Med] 2021 May 26; Vol. 13 (595).
Autor:
Seyrek, Kamil1 (AUTHOR), Espe, Johannes1 (AUTHOR), Reiss, Elisabeth1 (AUTHOR), Lavrik, Inna N.1 (AUTHOR) inna.lavrik@med.ovgu.de
Publikováno v:
Cells (2073-4409). Nov2024, Vol. 13 Issue 21, p1814. 33p.
Autor:
Gao, Xiao1 (AUTHOR), Yang, Hao‐Xu1 (AUTHOR), Cheng, Shu1 (AUTHOR), Cai, Hua‐Man1 (AUTHOR), Xiong, Jie1 (AUTHOR) xiongjie_sih@163.com, Zhao, Wei‐Li1,2 (AUTHOR) zhao.weili@yahoo.com
Publikováno v:
Clinical & Translational Discovery. Oct2024, Vol. 4 Issue 5, p1-13. 13p.
Autor:
Bagneris, C, Rogala, K, Baratchian, M., Zamfir, V.S., Kunze, M.B.A., Dagles, S, Pirker, K.F., Collins, M., Hall, B.A., Barrett, Tracey E., Kay, C.W.M.
Viral flice interacting protein (vFLIP), encoded by the oncogenic Kaposi's sarcoma associated herpes virus (KSHV), constitutively activates the canonical nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) pathway. This is achieve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::f0c85a1b3d762a215c06b34f7d33e818
https://eprints.bbk.ac.uk/id/eprint/12348/1/jbc.M114.622928.full.pdf
https://eprints.bbk.ac.uk/id/eprint/12348/1/jbc.M114.622928.full.pdf
Autor:
Baratchian, M.
Activation of the NF-κB pathway is linked to cancer development and progression. Kaposi’s sarcoma-associated herpesvirus (KSHV/HHV8) encodes vFLIP which binds to the NEMO/IKKγ subunit of IKK and constitutively activates NF-κB, leading to tumouri
Externí odkaz:
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.639594