Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Baransel Kamaz"'
Autor:
Debra Van Egeren, Baransel Kamaz, Shichen Liu, Maximilian Nguyen, Christopher R. Reilly, Maria Kalyva, Daniel J. DeAngelo, Ilene Galinsky, Martha Wadleigh, Eric S. Winer, Marlise R. Luskin, Richard M. Stone, Jacqueline S. Garcia, Gabriela S. Hobbs, Franziska Michor, Isidro Cortes-Ciriano, Ann Mullally, Sahand Hormoz
Publikováno v:
Exp Hematol
The JAK2-V617F mutation is the most common cause of myeloproliferative neoplasms. While experiments have shown that this gain-of-function mutation is associated with myeloid blood cell expansion and increased production of white cells, red cells and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::802e1ff61d5622f263265dc0ce9eb024
https://doi.org/10.1016/j.exphem.2021.12.364
https://doi.org/10.1016/j.exphem.2021.12.364
Autor:
Mathieu Gigoux, Morten O. Holmström, Roberta Zappasodi, Joseph J. Park, Stephane Pourpe, Cansu Cimen Bozkus, Levi M. B. Mangarin, David Redmond, Svena Verma, Sara Schad, Mariam M. George, Divya Venkatesh, Arnab Ghosh, David Hoyos, Zaki Molvi, Baransel Kamaz, Anna E. Marneth, William Duke, Matthew J. Leventhal, Max Jan, Vincent T. Ho, Gabriela S. Hobbs, Trine Alma Knudsen, Vibe Skov, Lasse Kjær, Thomas Stauffer Larsen, Dennis Lund Hansen, R. Coleman Lindsley, Hans Hasselbalch, Jacob H. Grauslund, Thomas L. Lisle, Özcan Met, Patrick Wilkinson, Benjamin Greenbaum, Manuel A. Sepulveda, Timothy Chan, Raajit Rampal, Mads H. Andersen, Omar Abdel-Wahab, Nina Bhardwaj, Jedd D. Wolchok, Ann Mullally, Taha Merghoub
Publikováno v:
Science Translational Medicine. 14
The majority of JAK2V617F-negative myeloproliferative neoplasms (MPNs) have disease-initiating frameshift mutations in calreticulin (CALR), resulting in a common carboxyl-terminal mutant fragment (CALRMUT), representing an attractive source of neoant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d5ff55140f482ee33ec173cfebf6e6b
https://doi.org/10.1126/scitranslmed.aba4380
https://doi.org/10.1126/scitranslmed.aba4380
Autor:
Javier Escabi, Jacqueline S. Garcia, Shichen Liu, Debra Van Egeren, Sahand Hormoz, Maria Kalyva, Isidro Cortes-Ciriano, Richard Stone, Fernando D. Camargo, Christopher R. Reilly, Martha Wadleigh, Gabriela S. Hobbs, Maximilian Nguyen, Franziska Michor, Daniel J. DeAngelo, Marlise R. Luskin, Ilene Galinsky, Ann Mullally, Baransel Kamaz, Eric S. Winer, Sachin Patel
Some cancers originate from a single mutation event in a single cell. For example, blood cancers known as myeloproliferative neoplasms (MPN) are thought to originate through the acquisition of a driver mutation (most commonly JAK2-V617F) in a hematop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::daa01840888c376414d926f555ce0ceb
https://doi.org/10.1101/2020.08.24.265058
https://doi.org/10.1101/2020.08.24.265058
Autor:
Mathieu Gigoux, Roberta Zappasodi, Joseph Park, Cansu Cimen Bozkus, Levi Mangarin, David Redmond, Svena Verma, Sara Schad, Mariam George, Divya Venkatesh, Arnab Ghosh, Zaki Molvi, Baransel Kamaz, Anna Marneth, William Duke, Matthew Leventhal, Max Jan, Vincent Ho, Gabriela Hobbs, Trine Knudsen, Vibe Skov, Lasse Kjær, Thomas Larsen, Dennis Hansen, R. Lindsley, Hans Hasselbalch, Jacob Grauslund, Mads Andersen, Morten Holmstrom, Timothy Chan, Raajit Rampal, Omar Abdel-Wahab, Nina Bhardwaj, Ann Mullally, Jedd Wolchok, Taha Merghoub
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A807-A807
BackgroundThe majority of JAK2V617F-negative myeloproliferative neoplasms (MPN) have disease-initiating frameshift mutations in calreticulin (CALR) resulting in a common novel C-terminal mutant fragment (CALRMUT), representing an attractive source of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5db9a23d25afa1d35fed82d9af00e11
https://doi.org/10.1136/jitc-2021-sitc2021.772
https://doi.org/10.1136/jitc-2021-sitc2021.772
Autor:
Maria Kalyva, Daniel J. DeAngelo, Maximilian Nguyen, Ilene Galinsky, Shichen Liu, Sahand Hormoz, Debra Van Egeren, Baransel Kamaz, Eric S. Winer, Christopher R. Reilly, Javier Escabi, Jacqueline S. Garcia, Richard Stone, Isidro Cortes-Ciriano, Ann Mullally, Fernando D. Camargo, Marlise R. Luskin, Sachin Patel, Franziska Michor, Martha Wadleigh, Gabriela S. Hobbs
Publikováno v:
Blood. 136:7-8
*equal contribution, #co-corresponding authors Although the JAK2V617F mutation is the most common MPN phenotypic driver mutation, the precise consequences of the mutation on the behavior of individual human hematopoietic stem cells (HSCs) in vivo rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ecbaab29aa98607a9d2e31e2eacd6ff
https://doi.org/10.1182/blood-2020-141643
https://doi.org/10.1182/blood-2020-141643
Autor:
Shichen Liu, Sahand Hormoz, Maximilian Nguyen, Maria Kalyva, Gabriela S. Hobbs, Sachin Patel, Ann Mullally, Baransel Kamaz, Eric S. Winer, Richard Stone, Christopher R. Reilly, Jacqueline S. Garcia, Martha Wadleigh, Isidro Cortes-Ciriano, Debra Van Egeren, Marlise R. Luskin, Javier Escabi, Fernando D. Camargo, Daniel J. DeAngelo, Ilene Galinsky, Franziska Michor
Publikováno v:
Cell Stem Cell. 28:514-523.e9
Summary Some cancers originate from a single mutation event in a single cell. Blood cancers known as myeloproliferative neoplasms (MPNs) are thought to originate when a driver mutation is acquired by a hematopoietic stem cell (HSC). However, when the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cec5fb46d8bf169a8303e5e49291ea5
https://doi.org/10.1016/j.stem.2021.02.001
https://doi.org/10.1016/j.stem.2021.02.001